Pre-operative Serum Albumin and Neutrophil-Lymphocyte Ratio are Associated with Prolonged Hospital Stay Following Colorectal Cancer Surgery
Rohit Gohil, Majed Rishi, Benjamin H. L. Tan
Journal of Advances in Medicine and Medical Research · pp. 481–487 · Published 28 Sep 2013
10.9734/BJMMR/2014/5444Abstract
Aims: Colorectal cancer is the third most common cancer in European populations. It has been shown previously that neutrophil-lymphocyte ratio (NLR), pre-operative albumin, and haemoglobin are useful prognostic indicators. The aim of this study was to assess how these factors influence the length of postoperative stay (LOS) following colorectal cancer surgery. Methodology: All patients undergoing elective colorectal resections for malignancy between 2010 and 2011 in Pilgrim Hospital, Boston, U.K. were considered for the study. Hospital archive systems were used to ascertain pre-operative NLR, albumin and haemoglobin levels. LOS was calculated from electronic discharge documents with day 1 being the day after surgery. Unifactorial and multifactorial analyses were performed to identify independent predictors of prolonged stay. Results: 196 patients were included in the study. Pre-operative haemoglobin was not associated with prolonged hospital stay. On univariate analysis, pre-operative serum albumin and pre-operative NLR were associated with prolonged hospital stay. On multivariate analysis, pre-operative serum albumin >34.5 g/dl (odds ratio, 0.47; 95% confidence interval, 0.24 – 0.92; p = 0.027) retained independent association for prolonged hospital stay .However, pre-operative NLR failed to reach statistical significance on multivariate analysis. Conclusions: Patients with low albumin and elevated NLR are more likely to have an increased hospital stay following colorectal cancer surgery. This may be useful for surgeons in terms of identifying the ‘high-risk’ patient post-operatively and allow for early intervention.
Cited by 20
Casalone V, Bellomo SE, Berrino E · Front Nutr · 2025
Zeleke AJ, Palumbo P, Tubertini P · Front Artif Intell · 2023
Taşcı Hİ. · Ulus Travma Acil Cerrahi Derg · 2022
An S, Shim H, Kim K · Ann Coloproctol · 2022
Jo YY, Han J, Park HW · JMIR Med Inform · 2021
Atrash AK, de Vasconcellos K. · South Afr J Crit Care · 2020
Güneş M. · Cureus · 2020
Daniel SK, Thornblade LW, Mann GN · PLoS One · 2018
Tarazona-Santabalbina FJ, Llabata-Broseta J, Belenguer-Varea Á · J Geriatr Oncol · 2019
Bailon-Cuadrado M, Perez-Saborido B, Sanchez-Gonzalez J · Int J Colorectal Dis · 2018
Showing 17 of 20 known citations — external sources report more than can currently be individually listed.
Related research
- Colorectal Cancer Risk and Prevention Knowledge among Adults Attending Public Health Facilities in Obudu, Cross River State, Nigeria — shares topic coverage
- The Use of Complete Blood Count as Inflammatory Biomarkers in Patients with Colorectal Cancers in Enugu State University of Science and Technology Teaching Hospital, Parklane Enugu — shares topic coverage
- Demographic and Histopathological Spectrum of Gastrointestinal Cancers Excluding Hepatobiliary System: A 10-Year Review from Makurdi, North Central Nigeria — shares topic coverage
- Fecal and Salivary Microbial Gene Markers for the Non-invasive Detection of Colorectal Cancer Progression — shares topic coverage
- Can Noninvasive Tests Substitute Endoscopy for Diagnosis of Colonic Diseases? — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
20
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.