Evaluation of Magnetosensitive Cytostatic Concentration and Different Mechanisms of their Antitumor Effects
Dmytro V. Demash, Natalia Yu. Lukianova, Vasyl F. Chekhun
Journal of Applied Life Sciences International · pp. 83–94 · Published 22 Jan 2015
10.9734/JALSI/2015/15179Abstract
The review covers different aspects of structural and functional features of magnetic nanoparticles. Especially those which are associated with their interaction with cells and cause development of oxidative stress, apoptosis disruption of DNA structure and cytoskeleton, changes in intracellular signal cascades etc. It is suggested that use of iron oxide nanoparticles for magnet-driven drug delivery in cancer therapy might be safe and promising because it can enhance antitumor effects of known cytostatic drugs.
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