Bladder Wall Thickness, Post-Void Residual Urine, and Prostate Volume Evaluation in Adult Patients with Bladder Outlet Obstruction

Abstract

Introduction: Bladder outlet obstruction (BOO) can lead to ascending infection, which may result in renal failure if left undiagnosed. BOO may also occur in the complete absence of symptoms and be identified first as a case of urinary retention. Aim: To determine the relationship between bladder wall thickness, prostate volume, and post-void urine volume with IPSS. Methods: A prospective study of 100 participants using ultrasound to evaluate post-void residual volume [PVR], Bladder wall thickness [BWT], and prostate volume with IPPS as the Gold standard. Results:  Mean age of participants with BOO was 62.6 years. Mean values were prostate volume 75.2 cm³, BWT 0.46cm, and PVR 61.02cm3. Association between PVR, BWT, and Prostate volume was 0.000, 0.006, and 0.006, respectively. Relationship between all three parametres and IPPS was significant [0.000]. Correlation coefficient between variables and IPPS was significant. Logistic regression analysis between parametres and mild IPPS showed BWT with a significance of 0.005. Logistic regression analysis between parametres and moderate IPPS showed BWT with a significance of 0.000. PVR had the highest sensitivity [68%] of the three parametres but the least specificity [42%]. ROC showed BWT with the largest area of 0.314 and PVR with the smallest [0.246]. Conclusion: Combined use of BWT and PVR can better distinguish moderate to severe symptomatic men from mildly symptomatic cases.