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Research Article Open access CC BY 4.0

Understanding the Factors Promoting Mother to Child Transmission of HIV/AIDS in Nigeria

Rosemary Nneka Udeji, Chidimma Anthonia Azike, Nelyn Akunna Okoye, Emeka John Aneke, Chinazor Cordelia Offor, Onyinyechukwu Uzoamaka Oka

Asian Journal of Research in Infectious Diseases · pp. 1–12 · Published 29 Apr 2024

10.9734/ajrid/2024/v15i5344

Abstract

Mother-to-child transmission (MTCT) of HIV/AIDS remains a significant public health challenge in Nigeria. This review aimed to identify and understand key factors promoting MTCT and assess the effectiveness of current prevention interventions. A systematic literature search was conducted across multiple databases using relevant keywords and approximately 57 individual literatures was reviewed. Studies focusing on MTCT in Nigeria published after 2015 were included. Eligible studies were critically appraised for quality and relevance. Findings indicate significant knowledge gap (such as misconceptions about transmission routes, limited understanding of prevention methods, delay in seeking testing and care and inconsistent adherence to Antiretroviral therapy) among pregnant women regarding HIV transmission, persistent stigma and discrimination hindering access to PMTCT services, and challenges within the healthcare system such as geographical disparities and inadequate provider training. Cultural practices, including breastfeeding and postnatal rituals, further exacerbate MTCT risk. Male partner involvement emerges as a crucial yet often overlooked aspect of PMTCT. Existing interventions showed moderate effectiveness, highlighting the need for tailored approaches. Strengthening multi-level interventions addressing social, economic, and cultural determinants, alongside culturally sensitive approaches and increased male engagement, are crucial to address MTCT and improve maternal and child health outcomes in Nigeria. Future research should focus on developing and evaluating interventions tailored to specific contexts and populations.

HIV/AIDS Mother-to-child transmission (MTCT) Nigeria pregnant women with AIDS prevention interventions stigma and discrimination

Cited by 2

Evaluating the Effectiveness of Prevention of Mother-to-Child Transmission (PMTCT) programs: A case study of Federal Medical Centre, Asaba

Ibukun Jacob Akinkunmi, Ayodapo Oluwadare Jegede, Ekedegwa Daniel Apeh · International Journal of STD & AIDS · 2025

Healthcare Infrastructure and Resource Barriers to Preventing Mother-to-Child Transmission of HIV in Ghana: Insights from a Qualitative Study

Awinaba Amoah Adongo, Dominic Nabil Bodpii, Robert Kuchengye Mokulogo · International Journal of Environmental Research and Public Health · 2026

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