Genomic Epidemiology of BRCA1/BRCA2; Breast Cancer Associated Genes and Use of Electronic Health Record to Reduce the Escalating Cost of Treatment
Journal of Advances in Medicine and Medical Research · pp. 333–345 · Published 31 Jul 2011
10.9734/BJMMR/2011/478Abstract
This project reviewed gene mutations which are associated with BRCA1 and BRCA2. From epidemiological perspective, the escalating cost of breast cancer management is due to the aging phenomenon of the female cohort in United States population. Innovative genomic sequencing techniques could continue to augment gene mutations beside the BRCA1/BRCA2 and TP53, PTEN, ST11/LKB1, CDH1, CHEK2, and ATM among others. To reduce the escalating cost of breast cancer management, the application of pharmacogenomic techniques, use of electronic health record and the most appropriate software could be applied for both primary prevention and chemoprevention. Physicians and other clinicians must hone their skills in advanced Mendelian genetics to become proficient in using statistical risk analysis and the appropriate IT software to recommend primary prevention to at risk breast cancer patients.
Cited by 5
· Advances in Human Services and Public Health
· Advances in Human Services and Public Health
Birendra Kumar · Omics Approaches in Breast Cancer · 2014
· Advances in Human Services and Public Health
E. William Ebomoyi · Public Health and Welfare
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