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Research Article Open access CC BY 3.0

Chemistry and Biological Importance of Heterocyclic Schiff’s Bases

Mithun Rudrapal, Biplab De

International Research Journal of Pure and Applied Chemistry · pp. 232–249 · Published 27 Jun 2013

10.9734/IRJPAC/2013/3996

Abstract

Schiff’s bases containing heterocyclic scaffolds have been known to possess a wide range of biological and pharmacological activities for a long time. In recent years, they have gained significant interest in the area of drug research and development owing to their broad bioactivities such as antibacterial, antifungal, anti-inflammatory, anticonvulsant, antiviral and anticancer activities. In this paper, biologically relevant Schiff’s bases derived from a diverse group of heterocyclic scaffolds have been intensively reviewed.  

Heterocyclic Schiff’s base biological activity lead molecule

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