Cardamom Derived Phytochemicals against Mycobacterium tuberculosis Causing  Tuberculosis

Bijan Pumar Patra; Bapujee Palai; Sarthak Siddhant Mishra; Sunil Jha; Dipankar Bhattacharyay

doi:10.9734/jpri/2020/v32i630508

Research Article Open access CC BY 4.0

Cardamom Derived Phytochemicals against Mycobacterium tuberculosis Causing Tuberculosis

Bijan Pumar Patra, Bapujee Palai, Sarthak Siddhant Mishra, Sunil Jha, Dipankar Bhattacharyay

Journal of Pharmaceutical Research International · pp. 132–135 · Published 15 May 2020

10.9734/jpri/2020/v32i630508

Abstract

Tuberculosis is a disease caused by severe infections by Mycobacterium tuberculosis, a pathogenic bacteria. These bacteria cause infections in humans and thus lead to an unhealthy life. Phytochemicals from cardamom plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that acetic acid can effectively deactivate histidinol dehydrogenase (H37Rv) thereby interrupting the life cycle of the organism.

Phytochemical cardamom Mycobacterium tuberculosis

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Bijan Pumar Patra, Bapujee Palai, Sarthak Siddhant Mishra, Sunil Jha, Dipankar Bhattacharyay (2020). Cardamom Derived Phytochemicals against Mycobacterium tuberculosis Causing Tuberculosis. Journal of Pharmaceutical Research International , 132–135. https://doi.org/10.9734/jpri/2020/v32i630508

Affiliations

Bijan Pumar Patra — Centurion University of Technology and Management, Odisha, India.
Bapujee Palai — Centurion University of Technology and Management, Odisha, India.
Sarthak Siddhant Mishra — Centurion University of Technology and Management, Odisha, India.
Sunil Jha — Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay — Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.

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