Changes in Some Testicular Biometric Parameters and Testicular Function in Cadmium Chloride Administered Wistar Rats
E. I. Ekhoye, E. K. Nwangwa, C. P. Aloamaka
Journal of Advances in Medicine and Medical Research · pp. 2031–2041 · Published 4 Jul 2013
10.9734/BJMMR/2013/2821Abstract
Introduction: Recently there has been an increased association between environmental factors and male infertility. Aims: In the present study, the effect of changes in testicular biometric parameters (weight and volume) and testicular function (Sperm count, morphology, testosterone level) in Cadmium chloride administered Wistar rats was studied. Methodology: Twenty male albino Wistar rats were randomized into four groups (n=5). Group A (control) received rat chow and water, while Group B, C and D received 15mg/L, 20mg/L and 25mg/L of Cadmium chloride respectively for 6 weeks. Result: There was a significant (P=.05) and dose dependent decrease in testicular function parameters in the rats and a significant (P=.05) and positive correlation between the biometric parameters and testicular function. Conclusion: The findings showed that Cadmium chloride has a deleterious effect on testicular function and biometric parameters of the testes may be important in the assessment of testicular function.
Cited by 16
Fidelis Oyakhire, Mathias Emokpae, Kelly Esezobor · Pathology and Laboratory Medicine · 2025
Oluwagbenga John Ogunbiyi, Joseph Tosin Apata, Rotimi Jude Jegede · Journal of Biomolecular Toxicology · 2025
Mega O. Oyovwi, Eze K. Nwangwa, Benneth Ben-Azu · Naunyn-Schmiedeberg's Archives of Pharmacology · 2020
ADEL ALKHEDAIDE, ZAFER SAAD ALSHEHRI, AYMAN SABRY · Molecular Medicine Reports · 2016
Ehitare Ikekhuamen Ekhoye, Samson Eshikhokhale Olerimi, Santos Ehizokhale Ehebha · Clinical and Experimental Reproductive Medicine · 2020
Rodrigo Andreo SANTOS, Fernando Miranda de VARGAS JUNIOR, Leonardo de Oliveira SENO · Revista Brasileira de Saúde e Produção Animal · 2016
Mohamed M. Ahmed, Samir A. El‐Shazly, Mohamed E. Alkafafy · Andrologia · 2018
Mayada R. Farag, R. M. Abd EL-Aziz, H. A. Ali · Environmental Science and Pollution Research · 2015
Tomilola Olaolu, Damilola Ajibola, Damilare Rotimi · Jundishapur Journal of Natural Pharmaceutical Products · 2021
Akinsomisoye Olumide Stephen, Owolabi Adegbenga Rotimi, Azeez Taoreed Adegoke · Brazilian Journal of Pharmaceutical Sciences · 2021
Showing 15 of 16 known citations — external sources report more than can currently be individually listed.
Related research
- Investigation of Protamine Genes (PRM1, PRM2) Polymorphism and Its Impact on Sperm Toroid Integrity in Males from Ahmedabad (India) — shares topic coverage
- Overview of Clomiphene Citrate Use in Male Hypogonadism and Infertility — shares topic coverage
- NGS and Male Infertility: Biomarkers Wanted — shares topic coverage
- Seminal Cell-Free DNA Test for the Management of Male Infertility — shares topic coverage
- Epidemiology and Clinical Profile of Male Infertility at the Fertilization Centre IRIFIV in Casablanca, Morocco, around 295 Cases — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
16
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.