Correlation between Serum Uric Acid with Type 2 Diabetes Mellitus and its Complications

Abstract

Type 2 diabetes mellitus is becoming more common over the world, making it a major health concern. Many research has been carried a link among both higher uric acid concentrations in the body and a higher incidence of type 2 diabetes mellitus. On a biochemical level, uric acid has been proved to have a negative impact on insulin sensitivity in animals. When nitric oxide, essential for glucose uptake, is suppressed, this occurs. The goal of this study is to review past research on the relationship between serum uric acid and diabetes type II in various parts of the world, as well as the prevalence of such a link. Articles were chosen using the PubMed database and EBSCO Information Services. We used all relevant publications to our review that dealt with the connection among both serum uric acid and diabetes type II, in addition to the other articles. Other publications that were not linked to this field were excluded. In this systematic review, serum uric Acid levels were found to be correlated to type 2 diabetes mellitus, metabolic syndrome and carotid artery disease. Atherosclerosis is more common in people with type 2 diabetes. The reliability of concentrations of uric acid levels in blood in predicting type 2 diabetes and enhancing prevention should be the focus of future study.