Diagnosis and Therapeutic Management of Chronic Gastritis in Dogs Using Triple Therapy
Dushyant Kumar, Devendra Kumar Gupta, Shobha Jawre, Aditya Pratap, Sachin Jain, Ranbir Jatav, Rita Tyagi, Harshit Kaur Sachdev, Riya Mathur, Chetanya Walia
Journal of Advances in Biology & Biotechnology · pp. 962–975 · Published 5 Feb 2025
10.9734/jabb/2025/v28i11953Abstract
Chronic gastritis, characterized by persistent vomiting and gastric mucosal inflammation, possess a significant challenge in veterinary practice. This six-month study aimed to diagnose and evaluate the therapeutic management of chronic gastritis in dogs using triple therapy. In this study chronic gastritis was diagnosed on the basis of history, clinical signs, haemato-biochemical parameters and endoscopy. Among the 30 dogs examined via endoscopy, 14 were confirmed positive based on visible gastric mucosal alterations. The parameters like age, sex and breed of each dog having chronic gastritis were recorded to study the distribution of condition. The highest cases of chronic gastritis were seen in dogs aged 1-3 years. Retrievers had the most cases among breeds and males were affected more than females. For therapeutic study, 12 confirmed cases of chronic gastritis were selected and randomly divided into 2 groups as G1 and G2, each group comprising of six dogs. However, six apparently healthy dogs were included as a healthy control group (G3). Group G1 received the Amoxicillin with sulbactam, Metronidazole and Pantoprazole while group G2 received Ofloxacin, Ornidazole and Esomeprazole. Endoscopic evaluations on day 0 and day 10 showed significant improvement in both groups, with G1 achieving an 83.33% recovery rate compared to 66.66% in G2. G1 treated with Amoxicillin with sulbactam, Metronidazole and Pantoprazole demonstrated greater reductions in vomiting frequency and endoscopic lesions, alongside better normalization of haemato-biochemical parameters.
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