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Research Article Open access CC BY 4.0

Evolving Trends and Changing Perspectives in ANCA Associated Vasculitis– A Review

Monali Rajendrakumar Sahu, Tanvi Dilip Wairagade, Sonali Dilip Wairagade, Ranjit S. Ambad, Dhruba Hari Chandi

Journal of Pharmaceutical Research International · pp. 207–212 · Published 20 Jul 2021

10.9734/jpri/2021/v33i37B32041

Abstract

Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a group of conditions characterized by inflammation and destruction affecting small to medium vessels accompanied by excess morbidity and mortality. These diseases present as multisystem diseases with variety of signs and symptoms. Earlier AAV were considered fatal diseases, however recent advances have changed them to chronic illnesses associated with morbidity& relapses. This review analyses recent developments in the pathogenesis, treatment and follow up of ANCA associated vasculitis.

Anti-neutrophil cytoplasmic antibody (ANCA) Vasculitis Microscopic polyangiitis (MPA) Granulomatosis with polyangiitis (GPA)

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