Autoimmune Hemolytic Anemia Revealing Sarcoidosis: A Case Report
Tounsi Haifa, Bouzouaya Hela, Feten Sbai, Hamdi Mohamed Salah, Ghachem Ikbel, Sbaihi Siwar, Amri Raja, Sbai Mohamed Ali
Asian Journal of Medical Principles and Clinical Practice · pp. 900–905 · Published 31 Oct 2025
10.9734/ajmpcp/2025/v8i2350Abstract
Hematological involvement in sarcoidosis is often characterized by lymphopenia and splenomegaly. However, auto-immune hemolytic anemia associated with sarcoidosis is scarcely reported. Herein, we report a novel case of this unusual clinical presentation. A 40-year-old female was admitted for a normocytic and regenerative anemia. The Coombs test was positive for anti-IgG attesting of its auto-immune origin. The CT scan showed multiple mediastinal and abdominal lymphadenopathies and a bilateral interstitial pattern in the lung. Further investigations were negative for infectious diseases, malignancies and auto-immune diseases. Labial biopsy showed the presence of a non-caseating granulomatosis supporting the diagnosis of systemic sarcoidosis. The association between the two conditions was deemed fortuitus. Oral steroids were used to achieve remission for both sarcoidosis and auto-immune hemolytic anemia.
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