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Research Article Open access CC BY 4.0

Acute Pancreatitis Complicated by Rapunzel Syndrome in a Patient with Incomplete Situs Inversus: A Case Report

Ichrak Bouali, Ilias El Azhari, Othmane Berrada, Nassima Fakhiri, Abdelhak Ettaoussi, Abdessamad Majd, Khadija Kamal, Abdelilah El Bakouri, Mounir Bouali, Khalid El Hattabi

Asian Journal of Research in Surgery · pp. 391–398 · Published 28 May 2026

10.9734/ajrs/2026/v9i2383

Abstract

Background: Situs inversus is a rare anatomical anomaly that renders surgical presentations atypical. The association of acute pancreatitis, a gastrointestinal trichobezoar, and Rapunzel syndrome in a patient with situs inversus is exceptional. Case Report: We report the case of a 17-year-old female patient with unknown situs inversus who presented with biochemical acute pancreatitis that progressed to multiple digestive perforations associated with gastrointestinal trichobezoars fulfilling the criteria for Rapunzel syndrome. Conclusion: This case highlights the importance of a thorough and multimodal diagnostic evaluation in the setting of acute abdominal symptoms, and the need to anticipate rare complications — particularly Rapunzel syndrome — in patients with congenital anatomical anomalies.

Situs inversus acute pancreatitis Trichobezoar rapunzel syndrome digestive perforation surgical emergency

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