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Research Article Open access CC BY 4.0

Global Cassava Food Supply and Occurrence of Ataxic Polyneuropathy and Konzo

O. S. A. Oluwole

European Journal of Nutrition & Food Safety · pp. 138–149 · Published 13 Mar 2015

10.9734/EJNFS/2015/11453

Abstract

Study was done to describe global cassava food supply, and its relationship to occurrence of ataxic polyneuropathy and konzo, which are attributed to exposure to cyanide from cassava food. Cassava food supply and occurrence of ataxic polyneuropathy and konzo in all countries from 1961 to 2011, and GDP data for 2011 were analyzed. Cassava food supply ≥ 10% of expected daily calorie need was compared with GDP and occurrence of ataxic polyneuropathy and konzo. About half a billion people live where cassava food supply was ≥180 kcal/person/day. Cassava food supply ≥180 kcal/person/day was associated with GDP per capita ≤$535, p<0.0001, and with occurrence of ataxic polyneuropathy or konzo, odds ratio 30 (95% CI 7–134). Strong association of high cassava supply with low income and with endemicity of ataxic polyneuropathy and konzo indicates that reduction of contribution of cassava to energy needs will reduce the burden of disease.

Cassava cyanide ataxic polyneuropathy konzo.

References (47)

  1. 1 Observations: Surface and Atmospheric Climate Change
  2. 2 Why are so many food plants cyanogenic? [DOI]
  3. 3 Cassava: A Basic Energy Source in the Tropics [DOI]
  4. 4 KONZO, AN EPIDEMIC UPPER MOTOR NEURON DISEASE STUDIED IN TANZANIA [DOI]
  5. 5 Persistent konzo and cyanogen toxicity from cassava in northern Mozambique [DOI]
  6. 6 Konzo and continuing cyanide intoxication from cassava in Mozambique [DOI]
  7. 7 Tropical myeloneuropathies [DOI]
  8. 8 Persistence of tropical ataxic neuropathy in a Nigerian community [DOI]
  9. 9 Wild Manihot species: botanical aspects, geographic distribution and economic value [DOI]
  10. 10 The effects of processing techniques in reducing cyanogen levels during the production of some Cameroonian cassava foods [DOI]
  11. 11 Incidence of endemic ataxic polyneuropathy and its relation to exposure to cyanide in a Nigerian community [DOI]
  12. 12 Neurological disorders associated with cassava diet: a review of putative etiological mechanisms [DOI]
  13. 13 AN ATAXIC NEUROPATHY IN NIGERIA [DOI]
  14. 14 Studies on cassava, Manihot utilissima Pohl—I. Cyanogenesis: The biosynthesis of linamarin and lotaustralin in etiolated seedlings [DOI]
  15. 15 An Investigation into an Acute Outbreak of ‘Central Neuritis’ [DOI]
  16. 16 The biosynthesis of cyanogenic glucosides in roots of cassava [DOI]
  17. 17 An epidemic of optic neuropathy in Tanzania: Characterization of the visual disorder and associated peripheral neuropathy [DOI]
  18. 18 Epidemic optic and peripheral neuropathy in Cuba: A unique geopolitical public health problem [DOI]
  19. 19 Fate in humans of dietary intake of cyanogenic glycosides from roots of sweet cassava consumed in Cuba [DOI]
  20. 20 Exposure to cyanide following a meal of cassava food [DOI]
  21. 21 Clinical and Etiological Profile of Tropical Ataxic Neuropathy in Kerala, South India [DOI]
  22. 22 Konzo outbreak among refugees from Central African Republic in Eastern region, Cameroon [DOI]
  23. 23 Low prevalence of ataxic polyneuropathy in a community with high exposure to cyanide from cassava foods [DOI]
  24. 24 Determination of cyanide in soybeans and soybean products [DOI]
  25. 25 Konzo and dietary pattern in cassava-consuming populations of Popokabaka, Democratic Republic of Congo [DOI]
  26. 26 A Survey of Total Hydrocyanic Acid Content in Ready-to-Eat Cassava-Based Chips Obtained in the Australian Market in 2008 [DOI]
  27. 27 CLINICAL AND PATHOLOGICAL OBSERVATIONS ON JAMAICAN NEUROPATHY [DOI]
  28. 28 Biochemical evidence of thiamine depletion during the Cuban neuropathy epidemic, 1992–1993 [DOI]
  29. 29 EVALUATION OF THE EFFECT OF VARIOUS PROCESSING TECHNIQUES ON CYANOGEN CONTENT REDUCTION IN CASSAVA [DOI]
  30. 30 Vitamin B nutrition in the Nigerian tropical ataxic neuropathy. [DOI]
  31. 31 The retail market for fresh cassava root tubers in the European Union (EU): the case of Copenhagen, Denmark — a chemical food safety issue? [DOI]
  32. 32 Tropical ataxic neuropathy in Liberians.
  33. 33 The role of thiamine deficiency in konzo [DOI]
  34. 34 PLASMA THIOCYANATE AND VITAMIN B12 IN NIGERIAN PATIENTS WITH DEGENERATIVE NEUROLOGICAL DISEASE [DOI]
  35. 35 The Medical Significance of Cyanogen in Plant Foodstuffs [DOI]
  36. 36 Controlled trial of hydroxocobalamin and riboflavine in Nigerian ataxic neuropathy [DOI]
  37. 37 Controlled trial of combinations of hydroxocobalamincystine and riboflavine-cystine, in Nigerian ataxic neuropathy [DOI]
  38. 38 Ataxic Neurological Syndrome Found in Tanganyika [DOI]
  39. 39 Geospatial association of endemicity of ataxic polyneuropathy and highly cyanogenic cassava cultivars [DOI]
  40. 40 Report on the effects of certain poisons contained in food-plants of West Africa upon the health of the native races.
  41. 41 Therapeutic effect of vitamin B complex on an ataxic syndrome in Western Nigeria [DOI]
  42. 42 Cyanogenicity of cassava varieties and risk of exposure to cyanide from cassava food in Nigerian communities [DOI]
  43. 43 High mortality of subjects with endemic ataxic polyneuropathy in Nigeria [DOI]
  44. 44 Nutritional aetiology of a neuropathy found in Tanganyika [DOI]
  45. 45 The causation of konzo : studies on a paralytic disease in Africa
  46. 46 [Cuban epidemic neuropathy].
  47. 47 Endemic ataxic polyneuropathy in Nigeria

Cited by 4

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