A Case Report and Review of Increased IgE in Patients with Transient Hypogammaglobulinemia of Infancy and Atopic Dermatitis after Normalization of IgG
Asian Journal of Pediatric Research · pp. 25–32 · Published 13 Feb 2023
10.9734/ajpr/2023/v11i2217Abstract
The coexistence of a high IgE level and transient hypogammaglobulinemia of infancy ( THI ) with atopic dermatitis (AD) is well known, but the coexistence with a marked serum IgE level ≥ 1000 IU/mL is a rare finding. Literature is scarce regarding IgE levels in patients with THI and AD after treatment with immunoglobulin (Ig). We reported a female infant 8 months old, with THI and severe AD. She was treated with intravenous immunoglobulin (IVIG) infusion after the failure of conventional therapy. Initially, serum levels of IgE were high, and serum levels of IgG were low. After 4 weeks of treatment with IVIG, patient profile showed normalization of IGE and higher elevation in IgG level. The present article is the first to describe a finding of marked IgE elevation (> 1000 IU/mL) after treatment with IVIG. Furthermore, our finding is supported by our review of increased IgE levels in patients with THI and AD who received IG therapy. According to our review different trend of IgE levels in patients who achieved spontaneous normalization of IgG was found.
Cited by 0
No indexed citations yet.
Related research
- Are Children Who Grow Up on Traditional Farms Protected From Asthma, Allergic Rhinitis and Allergic Sensitization? — shares topic coverage
- A Comparison of Mental Health Problems among Children with Alopecia Areata or Atopic Dermatitis and Their Parents — shares topic coverage
- Atopic Dermatitis among Children in Bamenda II, Cameroon: Prevalence and In-vivo Therapeutic Effects of Aqueous Extract of Cassia alata against DNCB Induced Atopic Dermatitis in Rats — shares topic coverage
- The Effectiveness of Combining Ipratropium Bromide and Salbutamol for the Treatment of Acute Severe Exacerbation of Asthma in Children: A Literature Review — shares topic coverage
- Foods Causing Highest IgG Immune Response in Saudi Arabia — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.