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Research Article Open access CC BY 4.0

In vitro Antioxidant and Anticancer Activity of Cyanobacteria

Dina A. Abd El Sadek, Ragaa A. Hamouda, Khalid Bassiouny, Hala Elharoun

Asian Journal of Medicine and Health · pp. 1–9 · Published 14 Aug 2017

10.9734/AJMAH/2017/34457

Abstract

Some cyanobacteria have therapeutic properties related to anticancer, antioxidant and antibacterial activity. The aim of the present study was to determine the polyphenol content together with antioxidant and anticancer activity against Ehrlich Ehrlich Ascites Carcinoma cell line in vitro of Anabaena oryzae, Calothrix marchica and Spirulina platensis‏, selecting the best alga for further investigations. The results indicate that methanol extracts of S. platensis‏ has the greatest polyphenol content, together with the highest antioxidant and anticancer activity in vitro followed by A. oryzae and C. marchica respectively. Based on gas chromatography/mass spectrometry analysis of S. platensis‏  methanol extract show that the most dominant content was octadecenoic acid methyl ester (ω- 9).   

Cyanobacteria Spirulina platensis antioxidant polyphenol content Ehrlich Ascites Carcinoma cell line (EAC)

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