Microbiological Enumeration of Pathogens Associated with Urinary Tract Infection: Current Scenario and Its Medical Relevance

Abstract

Background: Urinary tract infection (UTI) is the most common among community acquired infections worldwide affecting men as well as women, many reports suggested that uropathogens are becoming more resistant towards antibiotics, which can cause various problems during treatment. Methods: In this study, 48 samples were collected from the suspected patients and these samples were subjected to various clinical evaluations. Results: Among them 29 were females and 19 were males, in the studied cases E. coli (48.3%) was most frequently observed pathogens, S. aureus (29.03%).Among antibiotics, Tigecyclin (TGC) was the most effective antibiotic against all the three isolated bacteria, about 100% of bacteria showed the sensitivity towards it. E. coli was found to be the  most resistant bacteria against Tetracycline (TET) (66.6%) followed by Amoxiclav (AMC) (60%), Fosfomycin (Fo) (53.3%), Piperacilllin (PIP) (53.3%), Cefepime (CPM) (53.3%). Among K. pneumonia isolates had shown resistance against Tetracycline (TET) (57.1%), Fosfomycin (FO) (57.1%), Piperacillin (PI) (57.1%), Cephalexin (CZ) (57.1%) and Amikacin (AK) (57.1%). Staphylococcus aureus had shown maximum resistance against Tetracycline (TET) (66.5%), Co-amoxiclav (AMC) (66.5%) followed by Chloramphenicol (55.4%) and Cefepime (CPM) (55.4%). Conclusion: In conclusion UTI infection rates are higher among females, E. coli was the most causative agents of UTI and the emergence of resistance in bacteria is probably due to the overuse of antibiotics. Antibiotic Tigecyclin could be the drug of choice for the treatment of UTI.