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Research Article Open access CC BY 4.0

In vitro Anticancer and Antimicrobial Proprieties of Carica papaya against Biochemically Characterized Clinical and Standard Microbes

Nureen Zahra, Farheen Ansari, Sumaira Shaheen, Gulshan Parveen, Rabia Rasool, Modasrah Mazhar, Qaiser Akram, Muhammad Sajid Rasheed, Qurban Ali, Arif Mailk

Journal of Pharmaceutical Research International · pp. 23–30 · Published 10 Dec 2020

10.9734/jpri/2020/v32i3430961

Abstract

The bacterial pathogens have established various defense system against antimicrobial agents. The main mechanism of action of antibiotic resistance is obtained by pathogenic microorganisms, which directly involved in the diagnosis of various therapeutic plants with their significant antimicrobial properties. The current study investigated the antimicrobial and anticancer properties of Carica papaya. Fresh sample of C. papaya was collected in the native area of Punjab and selected isolate were tested against the aqueous, chloroform, ethanol, methanol extracts of C. papaya and anti-microbial activity by disc diffusion method. Anticancer activity was carried out in the HeLa cell line in above mention fractions of the extract at different concentration. The present study concluded, the extracts of the specific plants, particularly the ethanol and methanol extracts established the potential role against bacterial strain and HeLa cell line. It has also been concluded that these extracts might be implicated as natural products and serve to mediate as novel pharmaceuticals and therapeutic drugs.

Carica papaya antifungal anticancer drugs pathogens hela cell lines

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