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Research Article Open access CC BY 4.0

Plummer-Vinson Syndrome Associated with Celiac Disease: A Case Report

F. Haddad, H.H. Abakar, N. Khaireh Amoud, Z. Boukhal, FZ El Rhaoussi, M. Tahiri, W. Hliwa, A. Bellabah, W. Badre

Asian Journal of Research and Reports in Gastroenterology · pp. 242–247 · Published 11 Oct 2025

10.9734/ajrrga/2025/v8i1184

Abstract

Plummer-Vinson Syndrome (PVS), also known as Paterson-Kelly syndrome, is a rare condition characterized by cervical dysphagia associated with iron-deficiency anemia and the presence of a web in the upper esophagus. The association of this syndrome with celiac disease is not well known. Aim : We report a case of a patient with PVS associated with celiac disease. Case report : A 48-year-old woman was hospitalized for the management of high dysphagia accompanied by an anemic syndrome. The diagnosis of PVS associated with celiac disease was established. The patient was treated with iron supplementation and endoscopic dilation of the esophageal web, along with a gluten-free diet. Conclusion : Celiac disease is a classic cause of iron-deficiency anemia and should be considered an etiological factor in sideropenic dysphagia. Since both Plummer-Vinson syndrome (PVS) and celiac disease are each associated with an increased risk of pharyngeal and esophageal cancer, regular follow-up of these patients is essential.

Plummer-Vinson syndrome celiac disease endoscopic dilation iron supplementation gluten-free diet

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