Correlation between Anti-Mullerian Hormone Levels and Sexual Dysfunction in Infertile Women

Abstract

Aim: The purpose of the study was to evaluate the correlation between Anti-Mullerian hormone (AMH) levels and sexual dysfunction in infertile women. Methods: This prospective cross-sectional study was done on 558 infertile women. The participants were divided into three different AMH groups i.e. first AMH group (poor responder with ≤3 oocytes), second AMH group (normoresponder with 4–9 oocytes), and third AMH group (high responder with ≥10 oocytes). The values of the total Female Sexual Function Index (FSFI) variable were divided into three FSFI levels: level 1 (below 23), level 2 (between 23 and 29), and Level 3 (above 30).  The participants were divided into two groups: the first group with normal weight (BMI<25) and the second group with overweight (25<BMI<30). The FSFI questionnaire as a standardized and validated self-report was applied for measurement of the female sexual dysfunction.  Results:  The mean age of the participants was 30.14 years and the mean BMI was 24.81. 64.87% of the participants had normal weight and 35.13% had overweight. Regarding the total FSFI levels, 55.4% of the participants are at level 1, 42.3% at level 2, and 2.3% at level 3. The first AMH group had a mean of 0.58±0.27, the second AMH group had a mean of 2.38±0.89, and the third group had a mean of 6.42±1.58.  There was a significant difference among the three AMH groups in terms of all total FSFI subdomains. The participants at total FSFI level 1 had p-value=0.00, those at level 2 had p-value=0.00 and those at Level 3 had p-value=0.005.  Conclusion: Sexual dysfunction is reversely correlated with AMH. The participants with overweight had higher AMH value. To overcome female sexual dysfunction among infertile women, it is necessary to have sexual counseling, determine the factors affecting sexual dysfunction, and provide appropriate treatment.