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Research Article Open access CC BY 4.0

Rhabdomyolysis Triggered by Statin Use: A Case Report

Jafrin Sadiq Abdul Razack, Shoaib Shah Ahamed, Noel George Cherian, Ajmal Sainul, Aia Nana, Antony Calvin Ossanam

Asian Journal of Research in Nephrology · pp. 71–75 · Published 8 Jul 2025

10.9734/ajrn/2025/v8i197

Abstract

Rhabdomyolysis is a serious condition marked by the rapid breakdown of skeletal muscle, leading to the release of intracellular contents that can cause complications such as acute kidney injury (AKI). Statins are a known, though rare, cause of rhabdomyolysis. We report a case of severe statin-induced rhabdomyolysis in a male patient presenting with AKI and markedly elevated creatine phosphokinase levels. Despite supportive treatment with IV fluids and bicarbonate, he required hemodialysis. Following multiple sessions and continued care, his renal function and symptoms gradually improved. This case highlights the importance of early recognition and intervention in statin-associated rhabdomyolysis to prevent irreversible renal damage.

Rhabdomyolysis skeletal muscle statin therapy acute kidney injury

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