In vivo Action on the Hemogram of Oryctolagus cuniculus of Mucuna pruriens and Millettia pinnata (Fabaceae) Minerals

Abstract

Aims: Evaluate the in vivo activity of minerals from two plants on hematological parameters. Place and Duration of Study: Department of Biochemistry-Microbiology and at the laboratory of Daloa Hospital (Côte d'Ivoire), between December 2019 and April 2020. Methodology: During this study, twenty-seven rabbits, seventeen males and ten females were used. For its realization, two portions were carried out (experimental and control). The experimental portion consisted of seven batches of three rabbits (two males and one female), while the control portion consisted of two batches of three males and three females for each batch. Each rabbit of the two portions was collected separately in a purple tube (EDTA) with the only difference that for the experimental portion, a given rabbit was first scarified and then a previously prepared precise potion (P) was separately applied to the scarified area of the rabbit and blood was collected from day 4 onwards for analysis of hematological parameters. Results: This study reveals that: • P1 (ashes of Mucuna pruriens, Millettia pinnata and viper skull) and P3 (ashes of Millettia pinnata) have a stimulating activity on hematopoiesis. • P1, P3, P4 (ashes of viper skull), P6 (ashes of viper skull and Mucuna pruriens) and P7 (ashes of viper skull and Millettia pinnata) have a stimulating action on the synthesis of hemoglobin. • P1, P2, P3, P5 (ashes of Mucuna pruriens and Millettia pinnata), P6 and P7 induce hyperlymphocytosis in some animals; whereas P1, P3 and P6 promote hyperleukocytosis in each female of lots 3; 5 and 8. • P2 (Mucuna pruriens ash), P3, P5, P6 and P7 induce thrombocytosis in females of the various lots; while P1, P2, P4, P6 and P7 promote thrombocytopenia in some animals. Conclusion: Minerals from the two plants have different effects on rabbit hematological parameters.