Management Strategies for Heart Failure with Preserved Ejection Fraction (HFpEF): A Systematic Review and Meta-analysis
Raheel Chaudhry, Arhum Mahmood, Akbar Khan, Muhammad Sohail S. Mirza, Rubela Ray, Kainat Asif, Hasher Khan
Journal of Advances in Medicine and Medical Research · pp. 303–321 · Published 27 Apr 2024
10.9734/jammr/2024/v36i55439Abstract
Background: Heart failure with preserved ejection. Fraction is a set of clinical symptoms that raises mortality and morbidity. It should be addressed promptly and appropriately. Aims: The current systematic review examines management strategies for heart failure patients with preserved ejection fraction (HFpEF). Materials and Methods: PICOS scheme was followed in the development of eligibility criteria. Different databases like PubMed, Google Scholar, etc were searched for the primary studies. Results: The final sample included 21 studies that were manually selected. This meta-analysis found that beta-blockers and ace inhibitors significantly reduced mortality and hospitalizations as primary outcomes. Conclusion: To summarize, the study found that beta blockers and ACE inhibitors reduce mortality in heart failure patients with preserved ejection fraction. However, more research is needed to support this study.
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