Phytochemical Screening and Antimicrobial Activity of Three Medicinal Plants against Urinary Tract Infection Pathogens
R. U. B. Ebana, U. O. Edet, U. M. Ekanemesang, C. A. Etok, G. M. Ikon, M. K. Noble
Asian Journal of Medicine and Health · pp. 1–7 · Published 30 Sep 2016
10.9734/AJMAH/2016/29460Abstract
Urinary tract infections are a global health issue. Although antibiotics exist, most people for fear of stigmatization often prefer medicinal treatments. Three plants Acanthus montanus, Aspilia africana and Desmodium velutinum were investigated for their antimicrobial activity against human urinary tract infection pathogens and also screened for phytochemicals. The phytochemical screening and quantification, characterisation of isolates, antimicrobial screening and minimum inhibitory concentration were all done using standard techniques. Replicate readings were then subjected to analysis of variance. The results of the phytochemical screening and quantification of the plants showed the presence alkaloids (2.40 – 3.12%), glycosides (3.50 – 4.20%), saponins (3.02 -- 6.27%), tannins (0.17 – 0.47%), flavonoids (9.22 – 11.42%), polyphenol (9.72 – 9.90%) and reducing compounds (7.40- 9.18 mg %) in studied plants. Analysis of the replicate readings showed significance (p < 0.05). The results of the microbial characterization showed that isolates were Esherichia coli, Staphylococcus species and Pseudomonas aeruginosa. The antimicrobial sensitivity assay showed that the isolates responded differently to the test plants extracts. Staphylococcus species and E. coli were more sensitive to the test extracts than P. aeruginosa. The least inhibition was 11.50 mm while the highest was 14.00 mm. Consistently, all the studied plants showed very good inhibition at a minimum inhibitory concentration of 200 mg. The findings in this study confirms their use in the treatment of urinary tract pathogen and the need for further studies aimed at determining the bioactive compounds in these plants.
Cited by 11
G. Ndukwe, O. F. Okoronkwo, I. R. Jack · Nigerian Journal of Chemical Research · 2024
G. Oboh, A. Atoki, A. Ademiluyi · Food Science & Nutrition · 2023
F. N. Osuala, Kehinde Shogo Fagbenja, P. Mounmbegna · Magna Scientia Advanced Research and Reviews · 2021
Sarita Das · Future Journal of Pharmaceutical Sciences · 2020
A. Igwe, C. Eleazu · Food Science & Nutrition · 2017
Dr. Parag Deshmukhe, D. Kore · 2021
C. Mboto, U. Edet, E. Mbim · 2018
Kusum Lata Bairagi
Universidad de Cuenca, Alexander Cueva-Chamba, Freddy Bustamante-Pacheco · Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas · 2023
Ian Cock, Nothando Mavuso, Sandy Van Vuuren · Evidence-Based Complementary and Alternative Medicine · 2021
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
11
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.