An Overview of the Epidemiology, Pathogenesis, Diagnosis, and Treatment of Human Parvovirus B19
Kumaran Vadivel, Balaji Nandagopal, Mageshbabu Ramamurthy, Nithiyanandan Saravanan, Prashanth Rajendiran
Asian Journal of Research in Infectious Diseases · pp. 32–43 · Published 1 Dec 2022
10.9734/ajrid/2022/v11i4226Abstract
Human Parvovirus B19 (HPV-B19) infections are reported from different parts of the globe. The infection occurs in all age groups; however, most infections occur in childhood. There is evidence of exposure to the virus in about 80% of adults when screened for specific IgG. HPV-B19 is incriminated in several conditions like erythema infectious, aplastic crisis, hydrops fetalis and arthropathy. HPV-B19 is a cause of the Fifth disease (erythema infectious); it could also cause a febrile illness with or without rash in adults. Many adults especially women develop arthropathy and the condition could be chronic following a febrile illness. Patients (adults) with End Stage Renal Disease (ESRD) are prone to develop aplastic crisis or chronic anemia [1]. This review article aims to comprehensively describe the etiology, epidemiology, clinical features, diagnostic methods, and treatment in the management of HPV-B19.
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