Chronic Total Occlusion of Coronary Left Main Artery Supplied by Right Collaterals under Vascular Endothelial Growth Factor Inhibitor Therapy
K. Chawki, E. M. Rochd, M. Selmaoui, A. El Jazouli, M. HABOUB, S. AROUS, G. Bennouna, A. DRIGHIL, R. HABBAL
Asian Journal of Cardiology Research · pp. 328–332 · Published 18 Aug 2023
Abstract
We report a rare case of a patient who despite being under anti VEGF : Bevacizumab , developed a large coronary collateral circulation completely supplying the chronic total occlusion of left main coronary artery. Bevacizumab, a monoclonal antibody was the first potent angiogenic inhibitor , targeting vascular endothelial growth factor (VEGF)-A. Some of it's important cardiovascular adverse events include arterial and venous thrombotic events, coronary artery disease and heart failure resulting from inhibition of endothelial regeneration. Our patient developed dyspnea after 1 year of receiving bevacizumab with a chronic total occlusion of the left main coronary artery with the particularity of developing extensive collaterals despite the anti VEGF treatment she received.
Cited by 0
No indexed citations yet.
Related research
- Oxidative Stress Biomarkers (Malondialdehyde, Superoxide Dismutase, and Catalase) as Predictors of Cardiovascular Disease Risk: A Review — shares topic coverage
- - 251 A/T Single Nucleotide Polymorphism of Interleukin 8 and Susceptibility to Acute Myocardial Infarction — shares topic coverage
- The Relation of Vitamin D Status and Presence of Acute Coronary Syndrome in Patients — shares topic coverage
- Arginase Activity as a Useful Cardiac Marker for Differential Diagnosis of UA and MI: A Pilot Study — shares topic coverage
- Angiotensin-I-Converting Enzyme (ACE) Insertion/Deletion Polymorphism in Egyptian Patients with Coronary Artery Disease — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.