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Research Article Open access CC BY 4.0

Phytochemical Screening and Cytotoxic Analysis of Three Local Vegetables Used in the Treatment of Bacterial Diarrhoea in Southern Benin (West Africa): A Comparative Study

A. J. Agbankpé, S. H. Bankolé, F. Assogba, T. V. Dougnon, B. Yèhouénou, J. Gbénou, L. Baba-Moussa

Biotechnology Journal International · pp. 1–13 · Published 27 Sep 2015

10.9734/BBJ/2015/19123

Abstract

The use of plants in traditional medicine become very common nowadays throughout the world and in developing countries in particular. The current study was carried out aiming to compare the chemical features of three vegetables (Vernonia amygdalina, Crateva adansonii and Sesamum radiatum) mostly used for human consumption and traditional medicine to treat bacterial diarrhoea in Benin. These vegetables were selected among the 27 species obtained after ethno-botanical investigations in southern Benin. Therefore, the major chemical groups contained in these vegetables were detected by solubility assays together with coloration and precipitation reactions. Furthermore, cytotoxicity of the plant extracts was assessed on shrimp larvae (Artemia salina). The results showed that gallic tannins, flavonoids, alkaloids, mucilages, coumarins and reducing compounds were detected in all samples (100%) followed by cathechic tannins (66.66%) and saponins (33.33%). The study also revealed that none of the studied vegetables is cytotoxic (LC50 > 0.01 mg/ml). This study was conducted in the perspective of establishing innovations capable of assisting to; manufacture Improved Traditional Medicines for the treatment of bacterial diarrhoea in the future. Besides, it pointed out the presence of secondary metabolites and the cytotoxicity of these vegetables interesting for further antibacterial, antidiarrheal and pharmacological studies.

Vernonia amygdalina Crateva adansonii Sesamum radiatum phytochemical screening cytotoxicity

References (25)

  1. 1 A Method of Computing the Effectiveness of an Insecticide [DOI]
  2. 2 Plant Products as Antimicrobial Agents [DOI]
  3. 3 African Indigenous Vegetables: An overview of the cultivated species.
  4. 4 Laboratory Handbook for the Fractionation of Natural Extracts [DOI]
  5. 5 A comparison between two brine shrimp assays to detect in vitrocytotoxicity in marine natural products [DOI]
  6. 6 Comparative study of the assay of and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts [DOI]
  7. 7 Contribution to the ethnobotanical, phytochemical and pharmacological studies of traditionally used medicinal plants in the treatment of dysentery and diarrhoea in Lomela area, Democratic Republic of Congo (DRC) [DOI]
  8. 8 Nutritional and chemical value of Amaranthus hybridus l. leaves from Afikpo, Nigeria [DOI]
  9. 9 Diversity of the Neglected and Underutilized Crop Species of Importance in Benin [DOI]
  10. 10 Phytochemical and nutrient evaluation of Carica papaya (pawpaw) leaves.
  11. 11 NUTRITIONAL AND PHYSIOLOGICAL IMPLICATIONS OF SAPONINS: A REVIEW [DOI]
  12. 12 Potential Toxicity of Some Traditional Leafy Vegetables Consumed in Nyang’oma Division, Western Kenya [DOI]
  13. 13 Proximate and Phytochemical Analyses of Solanum aethiopicum L. and Solanum macrocarpon L. Fruits
  14. 14 Phytochemical screening and assessment of antibacterial activity for the bioactive compounds in Annona muricata
  15. 15 A Study Review of Documented Phytochemistry of Vernonia amygdalina (Family Asteraceae) as the Basis for Pharmacologic Activity of Plant Extract
  16. 16 Etude ethnobotanique des légumes feuilles thérapeutiques utilisés dans le traitement des diarrhées au sud-Bénin (Afrique de l’Ouest) [DOI]
  17. 17 Phytochemical screening and toxicity studies of Crassocephalum rubens (Juss. ex Jacq.) S. Moore and Crassocephalum crepidioides (Benth.) S. Moore consumed as vegetable in Benin
  18. 18 Phytochemical Screening, Nutritional and Toxicological Analyses of Leaves and Fruits of Solanum macrocarpon Linn (Solanaceae) in Cotonou (Benin) [DOI]
  19. 19 Agromorphological characterization of Sesamum radiatum (Schum. and Thonn.), a neglected and underutilized species of traditional leafy vegetable of great importance in Benin) [DOI]
  20. 20 Nutritional, phytochemical and antimicrobial properties of two wild aromaticvegetables from Edo State
  21. 21 Phytochemical Screening and Anti-nociceptive Properties of the Ethanolic Leaf Extract of Trema Cannabina Lour [DOI]
  22. 22 Preliminary phytochemical screening, in-vitro antioxidant and cytotoxic activity of five different extracts of Moringa oleifera leaf
  23. 23 Caractéristiques physico-chimiques, phytochimiques et toxicité des espèces végétales utilisées comme emballages alimentaires en Afrique de l’Ouest [DOI]
  24. 24 Comparison of nutritional values of Vernonia amygdalina, Crateva adansonii and Sesamum radiatum: three main vegetables used in traditional medicine for the treatment of bacterial diarrhoea in southern Benin (West Africa).
  25. 25 ChemInform Abstract: Synthesis of Novel Triheterocyclic Thiazoles as Antiinflammatory and Analgesic Agents. [DOI]

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