Near-Fatal Hepatic Crisis in A Sickle Cell Disease School-Going Child
Lere P. Oluwadare, Pauline K. Akowundu, Christian E. Amiwero, Adebowale T. Odunafolabi, Sampson C. Aliozor, Oluwasegun A. Adebisi, Abimbola S. Ajayi, Odutola I. Odetunde
Asian Hematology Research Journal · pp. 292–299 · Published 8 Dec 2025
10.9734/ahrj/2025/v8i4223Abstract
A 10-year-old girl, known Haemoglobin (Hb) SS patient (new to our facility, the Redeemer’s Health Village), presented on account of headache, abdominal pain, fever, paleness of the body and yellowness of the eyes. Pertinent examination findings revealed a school age female, conscious but lethargic, in significant painful distress, pale and deeply jaundiced. Liver function profile was grossly deranged. Radiological investigations were deferred because the child was gravely ill at presentation. Her level of consciousness became altered on the second day of admission (Hepatic Encephalopathy Grade III, West Haven Criteria). Urgent exchange blood transfusion was done with HbA blood. Her clinical status steadily improved. She was allowed home in the second week of admission. She has remained clinically stable during the outpatient clinic visits subsequently.
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