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Research Article Open access CC BY 4.0

Risk Factors for Extrapulmonary Tuberculosis in Bangladesh: A Country with High Tuberculosis Prevalence

Sayla Aktar Chowdhory, Sabina Sultana, Shampa Rani Pal, Sadia Islam Reya, Konika Rahman, Moni Krishno Mohanta, Md Ariful Hasan, Md Fazlul Haque

Asian Journal of Research in Infectious Diseases · pp. 169–182 · Published 28 Dec 2024

10.9734/ajrid/2024/v15i12412

Abstract

Tuberculosis (TB) is a major public health problem in Bangladesh. In this case-control retrospective study, a total of 348 patients, either with pulmonary TB (PTB) or extrapulmonary TB (EPTB), were surveyed from April 2020 to January 2023 from five different districts of Bangladesh to identify risk factors of EPTB. The results revealed that most of the surveyed TB patients were infected with PTB (225 patients) while 123 patients were infected with EPTB. Males were more susceptible to PTB while females were more prone to EPTB. EPTB was more prevalent in younger people than older people as compared with PTB. Likewise, married patients were more prone to PTB than EPTB while unmarried patients were equally susceptible to both PTB and EPTB. Brain, lymph node and intestine were major organs which were infected by EPTB, but the prevalence of EPTB of intestine, lymph node and breast were higher for female than for male. BCG vaccination showed more preventive role against EPTB than PTB. EPTB was prevalent in certain blood groups and occupations. Similarly, the people with very dark brown skin and underweight in childhood were more prone to EPTB. The data also revealed that family members with EPTB, regular medication, less exposure to direct sunlight, and mental stress increased the prevalence of EPTB. Contrary, addiction to smoking, average sleeping hours, and use of mosquito coil were dispensable factors affecting the prevalence of EPTB. All these findings emphasize the necessity for addressing specific risk factors, to decrease the burden of EPTB in Bangladesh.

Tuberculosis extrapulmonary risk factor Bangladesh

References (28)

  1. 1 The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling [DOI]
  2. 2 Risk Factors for Tuberculosis [DOI]
  3. 3 Extra-pulmonary manifestations in a large metropolitan area with a low incidence of tuberculosis.
  4. 4 Impact of socio-economic factors on Tuberculosis treatment outcomes in north-eastern Uganda: a mixed methods study [DOI]
  5. 5 Epidemiology and factors associated with Extra-pulmonary tuberculosis in a Low-prevalence area [DOI]
  6. 6 Extrapulmonary Tuberculosis: Update on the Epidemiology, Risk Factors and Prevention Strategies [DOI]
  7. 7 The Biological and Clinical Aspects of a Latent Tuberculosis Infection [DOI]
  8. 8 Effects of Gender and Age on Development of Concurrent Extrapulmonary Tuberculosis in Patients with Pulmonary Tuberculosis: A Population Based Study [DOI]
  9. 9 Epidemiology and the diagnostic challenge of extra-pulmonary tuberculosis in a teaching hospital in Ethiopia [DOI]
  10. 10 An epidemiological study of multi drug resistant tuberculosis cases registered under Revised National Tuberculosis Control Programme of Ahmedabad City.
  11. 11 Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis [DOI]
  12. 12 Prevalence, risk factors and health seeking behaviour of pulmonary tuberculosis in four tribal dominated districts of Odisha: Comparison with studies in other regions of India [DOI]
  13. 13 Prevalence of Antibiotic-Resistant Pulmonary Tuberculosis in Bangladesh: A Systematic Review and Meta-Analysis [DOI]
  14. 14 Knowledge, Attitudes and Health-seeking behaviour among Patients with Tuberculosis: A Cross-sectional Study [DOI]
  15. 15 Cathepsins and Their Endogenous Inhibitors in Host Defense During Mycobacterium tuberculosis and HIV Infection [DOI]
  16. 16 Latent tuberculosis infection in family members in household contact with active tuberculosis patients in Semarang City, Central Java, Indonesia [DOI]
  17. 17 Adolescent Females are More Susceptible than Males for Tuberculosis [DOI]
  18. 18 Clinical features, resistance patterns and treatment outcomes of drug-resistant extra-pulmonary tuberculosis: A scoping review [DOI]
  19. 19 Tobacco smoking-associated risk for tuberculosis: a case-control study [DOI]
  20. 20 Epidemiology of tuberculosis and treatment outcomes among children in Pakistan: a 5 year retrospective study [DOI]
  21. 21 A prospective study of socio-demographic, clinical characteristics and treatment outcomes of children with tuberculosis in Sindh, Pakistan [DOI]
  22. 22 High prevalence of TB disease in contacts of adults with extrapulmonary TB [DOI]
  23. 23 Risk Factors of Childhood Extrapulmonary Tuberculosis Compared to Pulmonary Tuberculosis in Bangladesh: A Hospital-based Study [DOI]
  24. 24 Targeting endogenous gaseous signaling molecules as novel host-directed therapies against tuberculosis infection [DOI]
  25. 25 Evaluation of Knowledge, Attitude and Practices of TB Diagnosed Patients in Rwanda towards TB Infection. Case of TB Diagnosed Patients in Kigali Urban and Rural Health Facilities
  26. 26 Distribution of ABO and Rh blood groups in patients with tuberculosis in Rohilkhand region of Uttar Pradesh [DOI]
  27. 27 An Epidemiological Study of Drug Resistant Tuberculosis Cases: Survey in the Northern Part of Bangladesh
  28. 28 Clinical spectrum and outcome of extra-pulmonary tuberculosis in children. [DOI]

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