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Research Article Open access CC BY 4.0

The Detailed Study of CD10: A Stromal Marker in Breast Carcinoma

Huidrom Jyotsna Devi, P. Karkuzhali, P. K. Baskaran, S. Mary Lilly

Journal of Pharmaceutical Research International · pp. 62–70 · Published 12 Apr 2021

10.9734/jpri/2021/v33i22B31399

Abstract

Breast carcinoma is one of the most frequently occurring cancers among women with one million cases. Breast cancer is the primary cause of death in women around the world. It is one of the major concerns in public health due to its high occurrence and growing tendency.   This complex functional structure develops from a highly modified apocrine sweat gland in the female, but remains rudimentary in male. Breast develops embryological into two lines along milk lines extending from axilla to groin. CD-10 is a 90- to 110-kDa cell surface zinc dependent metalloproteinase which is known as “Common Acute Lymphoblastic Leukaemia Antigen” (CALLA). CD-10 acts  as a stem cell regulator in the breast and  prevents uncontrolled proliferation on stem cells The present study is designed to study the expression of CD-10, a breast carcinoma stromal marker and its correlation with ER, PR and HER2/neu status in breast carcinoma.

Breast carcinoma CD-10 a stromal marker apocrine sweat gland

Cited by 1

A Study on Stromal Expression of CD10 Marker in Breast Carcinoma and Its Role as a Prognostic Marker in a Tertiary Care Center in South Kerala

K. P. Praveena, Jinu Abraham Glaxon, Aswathy Chandramohan · Archives of Medicine and Health Sciences · 2024

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