Treatment of Diabetic Foot Ulcer with Ointment Based on Ceratothoa oestroides Extract and Eosin- Case Report

Abstract

Aim: A case of a successful treatment using an ointment based on the olive oil extract of the isopod Ceratothoa oestroides and eosin sodium solution is described. Presentation of Case: Obese woman with unregulated Type 2 Diabetes Mellitus, renal impairment and smoker developed a severe  infected wound in a previously amputated area of the right lower extremity. She was treated for 10 months by topical application of the isopod ointment, eosin solution and for the first four months clindamycin (600 mg) and ciprofloxacin (200 mg) was orally administred. The treatment was evaluated by measurement of the transepidermal water loss, skin hydration, photodocumentation and planimetry. Discussion: Ten months after treatment, clinical evaluation, photo-documentation showed clearly that wound was almost healed. Wound area was reduced by 90%, transepidermal water loss by 36% and skin hydration was increased by 55%. These data seem very promising as the diabetic patient had damning characteristics concerning her health status in relation to wound healing process.  Conclusion: The combination of the C. oestroides ointment with the sodium eosin solution was effective in a grave case of diabetic foot ulcer. This significant healing effect should be further investigated.