The Relationship between Homocysteine ​​and Fragility Fractures - A Systematic Review

Alexandru Filip; Nina Filip; Bogdan Veliceasa; Cristiana Filip; Ovidiu Alexa

doi:10.9734/ARRB/2017/36176

Research Article Open access CC BY 4.0

The Relationship between Homocysteine and Fragility Fractures - A Systematic Review

Alexandru Filip, Nina Filip, Bogdan Veliceasa, Cristiana Filip, Ovidiu Alexa

Annual Research & Review in Biology · pp. 1–8 · Published 9 Sep 2017

10.9734/ARRB/2017/36176

Abstract

It is known that increased levels of homocysteine in plasma have been associated with various diseases. Current studies show that homocysteine is a new risk factor for the development of osteoporosis. Fragility fractures are associated with increased morbidity, mortality and cause substantial financial loss to the patients and their families. This mini-review provides a critical overview of currently available studies, examining the relationship between plasma homocysteine levels and fragility fractures. In conclusion more studies are needed to establish a clear relationship between homocysteine and fractures in elderly patients.

Hyperhomocysteine osteoporosis fracture methionine bone fragility.

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Alexandru Filip, Nina Filip, Bogdan Veliceasa, Cristiana Filip, Ovidiu Alexa (2017). The Relationship between Homocysteine and Fragility Fractures - A Systematic Review. Annual Research & Review in Biology , 1–8. https://doi.org/10.9734/ARRB/2017/36176

Affiliations

Alexandru Filip — Department of Orthopedics and Traumatology, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.
Nina Filip — Department of Biochemistry, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.
Bogdan Veliceasa — Department of Orthopedics and Traumatology, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.
Cristiana Filip — Department of Biochemistry, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.
Ovidiu Alexa — Department of Orthopedics and Traumatology, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.

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