Synthesis, Characterization and In vitro Cytotoxicity Assessment of Eggshell-derived β-CaSiO3 Nano Biomaterial
Boniface Tiimob, Vitus Apalangya, Tsemesgen Samuel, Shaik Jeelani, Vijaya Rangari
Current Journal of Applied Science and Technology · pp. 180–193 · Published 27 Mar 2015
10.9734/BJAST/2015/16811Abstract
This study explored the conversion of bio waste into a valued bioceramic material for potential tissue regeneration application. Calcium silicate (β-CaSiO3) nanomaterial was synthesized from waste egg shells (CaCO3) and silica (SiO2) precursors using noninvasive but sustainable and industrially scalable ball mill and sonochemical techniques. The development of the β-CaSiO3 NPs was monitored with Fourier transform infra-red spectroscopy (FTIR), thermogravimetric analysis (TGA), transmission electron microscope (TEM), field emission scanning electron microscopy / energy dispersive spectroscopy (FESEM-EDS) and X-ray diffraction (XRD). The results revealed the formation of polycrystalline nano-β-CaSiO3 with 100% peak at 2θ° = 30.0 in the (320) crystal planeand sizes less than 50 nm. In vitro cytotoxicity studies on human osteoblast cell line CRL 11372 suggests biocompatibility and non-interference with cell growth at concentrations ranging from 0.0781-1.250 mg/mLof β-CaSiO3.
Cited by 3
Salprima Yudha S, Aswin Falahudin, Noor Haida Mohd Kaus · Bulletin of Chemical Reaction Engineering & Catalysis · 2020
Boniface Jabik Tiimob, Shaik Jeelani, Vijaya Kumar Rangari · Journal of Applied Polymer Science · 2015
I O Oladele, B A Makinde-Isola, A A Adediran · Materials Research Express · 2020
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