Aldehydes: What We Should Know About Them

References (349)

1. 1 Feron, 1991, Aldehydes: Occurrence, Carcinogenic Potential, Mechanism of Action and Risk Assessment [DOI]
2. 2 Teranishi, R., Wick, E.L., and Hornstein, I. (1999). Flavor Chemistry. Flavor Chemistry: Thirty Years of Progress, Springer. [DOI]
3. 3 Takhar, 2023, Formation Pathways of Aldehydes from Heated Cooking Oils [DOI]
4. 4 Langton, 2006, Structure-activity Relationships for Skin Sensitization: Recent Improvements to Derek for Windows [DOI]
5. 5 Liao, 2021, Optical Chemosensors for the Gas Phase Detection of Aldehydes: Mechanism, Material Design, and Application [DOI]
6. 6 Ferreira, 2019, Development of a Method for Determination of Target Toxic Carbonyl Compounds in Must and Wine Using HS-SPME-GC/MS-SIM after Preliminary GC× GC/TOFMS Analyses [DOI]
7. 7 Aljaafari, M.N., Alkhoori, M.A., Hag-Ali, M., Cheng, W.H., Lim, S.H., Loh, J.Y., and Lai, K.S. (2022). Contribution of Aldehydes and their Derivatives to Antimicrobial and Immunomodulatory Activities. Molecules, 27. [DOI]
8. 8 Malik, S. (2019). Essential oils. Essential Oil Research, Springer. [DOI]
9. 9 Schober, 2023, Enzymatic Reactions towards Aldehydes: An Overview [DOI]
10. 10 Floss, M.A., Fink, T., Maurer, F., Volk, T., Kreuer, S., and Müller-Wirtz, L.M. (2022). Exhaled Aldehydes as Biomarkers for Lung Diseases: A Narrative Review. Molecules, 27. [DOI]
11. 11 Magnano, 2024, Exhaled Volatile Organic Compounds and Respiratory Disease: Recent Progress and Future Outlook [DOI]
12. 12 Lv, J.J., Li, X.Y., Shen, Y.C., You, J.X., Wen, M.Z., Wang, J.B., and Yang, X.T. (2023). Assessing Volatile Organic Compounds Exposure and Chronic Obstructive Pulmonary Diseases in US Adults. Front. Public Health, 11. [DOI]
13. 13 Calleja, 2019, Role of Aldehyde Dehydrogenases in Physiopathological Processes [DOI]
14. 14 Stras, A., Grassmann, A., Van Campenhout, P., Deconinck, E., Vanhaecke, T., and Desmedt, B. (2024). Analysis of Preservatives and Fragrances in Topical Medical Devices: The Need for More Stringent Regulation. Contact Dermat., in press. [DOI]
15. 15 World Health Organization (2024, October 18). Occupational and Environmental Health Team, Guidelines for Air Quality. Available online: https://apps.who.int/iris/handle/10665/66537.
16. 16 U.S. Environmental Protection Agency (2024, June 18). Fundamentals of Indoor Air Quality in Buildings, Available online: https://www.jm.com/en/blog/2019/november/fundamentals-of-indoor-air-quality-in-buildings/.
17. 17 Zhu, G., and Xiao, Z. (2022). Flavors and Fragrances: Structure of Various Flavors with Food Ingredients. Flavors and Fragrances in Food Processing: Preparation and Characterization Methods, ACS Publications. [DOI]
18. 18 Sowndhararajan, 2016, Influence of Fragrances on Human Psychophysiological Activity: With Special Reference to Human Electroencephalographic Response [DOI]
19. 19 SCCNFP (Scientific Committee on Cosmetic Products and Non-Food Products) (2024, June 18). The First Update of the Inventory of Ingredients Employed in Cosmetic Products. Section II: Perfume and Aromatic Raw Materials. SCCNFP/0389. Available online: www.leffingwell.com/cosmetics/out131_en.pdf.
20. 20 Maffei, 2014, Genotoxicity assessment of some cosmetic and food additives [DOI]
21. 21 EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) (2012). Scientific Opinion on Flavouring Group Evaluation 94, Revision 1 (FGE. 94Rev1): Consideration of aliphatic amines and amides evaluated in an addendum to the group of aliphatic and aromatic amines and amides evaluated by the JECFA (68th meeting). EFSA J., 10, 2747. [DOI]
22. 22 Min, 2022, Characterization of the Volatile Organic Compounds Produced from Green Coffee in Different Years by Gas Chromatography Ion Mobility Spectrometry [DOI]
23. 23 Cecchi, 2021, Virgin Olive Oil Volatile Compounds: Composition, Sensory Characteristics, Analytical Approaches, Quality Control, and Authentication [DOI]
24. 24 Ling, L., Wang, Y., Cheng, W., Jiang, K., Luo, H., Pang, M., and Yue, R. (2023). Research Progress of Volatile Organic Compounds Produced by Plant Endophytic Bacteria in Control of Postharvest Diseases of Fruits and Vegetables. World J. Microbiol. Biotechnol., 39. [DOI]
25. 25 Mohidem, N.A., Hashim, N., Shamsudin, R., and Che Man, H. (2022). Rice for Food Security: Revisiting its Production, Diversity, Rice Milling Process and Nutrient Content. Agriculture, 12. [DOI]
26. 26 Theloke, 2007, Compilation of a Database on the Composition of Anthropogenic VOC Emissions for Atmospheric Modeling in Europe [DOI]
27. 27 Alabdulhadi, 2019, Inhalation Exposure to Volatile Organic Compounds in the Printing Industry [DOI]
28. 28 McDonald, 2018, Volatile Chemical Products Emerging as Largest Petrochemical Source of Urban Organic Emissions [DOI]
29. 29 Gkatzelis, 2021, Observations Confirm that Volatile Chemical Products Are a Major Source of Petrochemical Emissions in U.S. Cities [DOI]
30. 30 Verma, 2019, Emission Estimation of Aromatic and Halogenated VOCs from Household Solid Fuel Burning Practices [DOI]
31. 31 Palmisani, 2020, Formation of Ozone-Initiated VOCs and Secondary Organic Aerosol Following Application of a Carpet Deodorizer [DOI]
32. 32 Davies, 2023, A measurement and modelling investigation of the indoor air chemistry following cooking activities
33. 33 2023, Do Synthetic Fragrances in Personal Care and Household Products Impact Indoor Air Quality and Pose Health Risks? [DOI]
34. 34 Asif, 2022, Estimation of Anthropogenic VOCs Emission Based on Volatile Chemical Products: A Canadian Perspective [DOI]
35. 35 Tran, V.V., Park, D., and Lee, Y.C. (2020). Indoor air pollution, related human diseases, and recent trends in the control and improvement of indoor air quality. Int. J. Environ. Res. Public Health, 17. [DOI]
36. 36 Ancione, 2021, Human health risk associated with emissions of volatile organic compounds due to the ship-loading of hydrocarbons in refineries [DOI]
37. 37 Mo, 2020, Volatile organic compound (VOC) emissions and health risk assessment in paint and coatings industry in the Yangtze River Delta, China [DOI]
38. 38 Mahilang, 2021, Biogenic Secondary Organic Aerosols: A Review on Formation Mechanism, Analytical Challenges and Environmental Impacts [DOI]
39. 39 Zhao, 2023, A systematic review of intermediates and their characterization methods in VOCs degradation by different catalytic technologies [DOI]
40. 40 Moloney, 2020, Reactions of Aldehydes and Ketones and Their Derivatives
41. 41 Junior, 2024, The Chemistry of Aldehydes and Ketones in the Synthesis of Heterocycles-Historical Reactions with a New and Green Perspective [DOI]
42. 42 Bai, 2024, Recent Advances in Trifluoromethylation of Olefins, Aldehydes, and Ketones [DOI]
43. 43 Arctander, S. (1994). Perfume and Flavor Chemicals (Aroma Chemicals), Allured Publishing Corporation.
44. 44 Kapadia, 2023, A Cross-Sectional Survey Analysis of the Human Olfactory Senses for Perfumes and its Alternations due to COVID-19 [DOI]
45. 45 Chen, T., Xue, Y., Li, C., Zhao, Y., Huang, H., Feng, Y., Xiang, H., and Chen, S. (2024). Identification of Key Volatile Compounds in Tilapia during Air Frying Process by Quantitative Gas Chromatography–Ion Mobility Spectrometry. Molecules, 29. [DOI]
46. 46 Atamaleki, 2022, Emission of aldehydes from different cooking processes: A review study [DOI]
47. 47 Zhang, 2023, Investigating Aldehyde and Ketone Compounds Produced from Indoor Cooking Emissions and Assessing their Health Risk to Human Beings [DOI]
48. 48 Hu, 2022, Effects of Roasting Temperature and Time on Aldehyde Formation Derived from Lipid Oxidation in Scallop (Patinopecten yessoensis) and the Deterrent Effect by Antioxidants of Bamboo Leaves [DOI]
49. 49 Wang, 2023, Particulate Matter and Volatile Organic Compound Emissions Generated from a Domestic Air Fryer [DOI]
50. 50 Rajendran, S., Silcock, P., and Bremer, P. (2023). Flavour Volatiles of Fermented Vegetable and Fruit Substrates: A Review. Molecules, 28. [DOI]
51. 51 Albarri, R., Vardara, H.F., Al, S., and Önal, A. (2024). Chromatographic Methods and Sample Pretreatment Techniques for Aldehydes, Biogenic Amine, and Carboxylic Acids in Food Samples. Crit. Rev. Anal. Chem., in press. [DOI]
52. 52 Amann, 2014, A Review of the Volatiles from the Healthy Human Body [DOI]
53. 53 Sarker, 2020, Synthesis, Characterization, Thermal Analysis and Antibacterial Activity of Cu(II) and Ni(II) Complexes with Thiosemicarbazone Derived from Thiophene-2-aldehyde
54. 54 Lin, J., Meng, H., Guo, X., Tang, Z., and Yu, S. (2023). Natural Aldehyde-Chitosan Schiff Base: Fabrication, pH-Responsive Properties, and Vegetable Preservation. Foods, 12. [DOI]
55. 55 Zhang, 2023, The Antioxidant and Antibacterial Activities of the Pyridine-4-aldehyde Schiff Bases Grafted Chloracetylchitosan Oligosaccharide Derivatives [DOI]
56. 56 Sinicropi, M.S., Ceramella, J., Iacopetta, D., Catalano, A., Mariconda, A., Rosano, C., Saturnino, C., El-Kashef, H., and Longo, P. (2022). Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities. Int. J. Mol. Sci., 23. [DOI]
57. 57 Vera, S., Landa, A., Mielgo, A., Ganboa, I., Oiarbide, M., and Soloshonok, V. (2023). Catalytic Asymmetric α-Functionalization of α-Branched Aldehydes. Molecules, 28. [DOI]
58. 58 Iacopetta, D., Ceramella, J., Catalano, A., Mariconda, A., Giuzio, F., Saturnino, C., Longo, P., and Sinicropi, M.S. (2023). Metal Complexes with Schiff Bases as Antimicrobials and Catalysts. Inorganics, 11. [DOI]
59. 59 Salem, 1960, Inhalation toxicities of some aldehydes [DOI]
60. 60 Vasanthy, M., Sivasankar, V., and Sunitha, T.G. (2022). Aldehydes’ Sources, Toxicity, Environmental Analysis, and Control in Food. Organic Pollutants: Toxicity and Solutions, Springer International Publishing. [DOI]
61. 61 LoPachin, 2014, Molecular Mechanisms of Aldehyde Toxicity: A Chemical Perspective [DOI]
62. 62 Laskar, 2019, Aldehyde Toxicity and Metabolism: The Role of Aldehyde Dehydrogenases in Detoxification, Drug Resistance and Carcinogenesis [DOI]
63. 63 Ren, 2019, Environmental Aldehyde Sources and the Health Implications of Exposure [DOI]
64. 64 Conklin, 2019, TRPA1 Channel Contributes to Myocardial Ischemia-Reperfusion Injury [DOI]
65. 65 Ribeaucourt, D., Bissaro, B., Lambert, F., Lafond, M., and Berrin, J.G. (2022). Biocatalytic Oxidation of Fatty Alcohols into Aldehydes for the Flavors and Fragrances Industry. Biotechnol. Adv., 56. [DOI]
66. 66 Zhou, 2020, Bioaldehydes and Beyond: Expanding the Realm of Bioderived Chemicals Using Biogenic Aldehydes as Platforms [DOI]
67. 67 Kazimírová, V., and Rebroš, M. (2021). Production of Aldehydes by Biocatalysis. Int. J. Mol. Sci., 22. [DOI]
68. 68 Wang, 2023, Recent Advances in the Photocatalytic Synthesis of Aldehydes [DOI]
69. 69 Dickey, R.M., Forti, A.M., and Kunjapur, A.M. (2021). Advances in Engineering Microbial Biosynthesis of Aromatic Compounds and Related Compounds. Bioresourc. Bioprocess., 8. [DOI]
70. 70 Liu, H., Ma, L., Chen, J., Zhao, F., Huang, X., Dong, X., Zhu, B., and Qin, L. (2023). Effect of Aliphatic Aldehydes on Flavor Formation in Glutathione–Ribose Maillard Reactions. Foods, 12. [DOI]
71. 71 Ding, 2020, Quantitative Measurements of Broad-band Mid-infrared Absorption Spectra of Formaldehyde, Acetaldehyde, and Acetone at Combustion-relevant Temperatures near 5.7 µm [DOI]
72. 72 Dattilo, 2022, Characterization of VOCs and Additives in Italian PET Bottles and Studies on Potential Functional Aldehydes Scavengers [DOI]
73. 73 Wang, 2023, Identification of Characteristic Aroma Compounds in Chicken Meat and their Metabolic Mechanisms Using Gas Chromatography-Olfactometry, Odor Activity Values, and Metabolomics [DOI]
74. 74 Wallington, T.J., Anderson, J.E., Dolan, R.H., and Winkler, S.L. (2022). Vehicle Emissions and Urban Air Quality: 60 Years of Progress. Atmosphere, 13. [DOI]
75. 75 Shi, 2020, Detection of Aliphatic Aldehydes by a Pillar[5]arene-based Fluorescent Supramolecular Polymer with Vaporchromic Behavior [DOI]
76. 76 Zheng, 2022, Recent Progress in Fluorescent Formaldehyde Detection Using Small Molecule Probes [DOI]
77. 77 Ahangar, 2023, O-doping Effects on the Adsorption and Detection of Acetaldehyde and Ethylene Oxide on Phosphorene Monolayer: A DFT Investigation [DOI]
78. 78 Pennings, 2020, Aldehyde and Volatile Organic Compound Yields in Commercial Cigarette Mainstream Smoke Are Mutually Related and Depend on the Sugar and Humectant Content in Tobacco [DOI]
79. 79 Api, 2015, Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients [DOI]
80. 80 (2024, October 18). REACH 2006. Regulation (EC) No. 1907/2006 (REACH) Official Journal of the European Union. Available online: https://osha.europa.eu/it/legislation/directives/regulation-ec-no-1907-2006-of-the-european-parliament-and-of-the-council.
81. 81 Brewer, 2015, An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells [DOI]
82. 82 Dou, 2017, Bright and Sensitive Ratiometric Fluorescent Probe Enabling Endogenous FA Imaging and Mechanistic Exploration of Indirect Oxidative Damage Due to FA in Various Living Systems [DOI]
83. 83 Blondel, 2011, Screening of Formaldehyde Indoor Sources and Quantification of Their Emission Using a Passive Sampler [DOI]
84. 84 Tang, 2016, Lysosome-Targeted Turn-On Fluorescent Probe for Endogenous Formaldehyde in Living Cells [DOI]
85. 85 Sutherland, 2008, Utility of Formaldehyde Cross-Linking and Mass Spectrometry in the Study of Protein–Protein Interactions [DOI]
86. 86 Zhu, 2019, Rapid and Sensitive Detection of Formaldehyde Using Portable 2-Dimensional Gas Chromatography Equipped with Photoionization Detectors [DOI]
87. 87 International-Agency-for-Research-on-Cancer (2006). Formaldehyde, 2-Butoxyethanol and 1-Tert-Butoxy-2-Propanol, World Health Organization.
88. 88 IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2006). Formaldehyde, 2-Butoxyethanol and 1-tert-Butoxypropan-2-ol. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, WHO.
89. 89 International Agency for Research on Cancer (2012). Chemical Agents and Related Occupations. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, WHO.
90. 90 Salthammer, 2015, The Formaldehyde Dilemma [DOI]
91. 91 Reingruber, 2018, Formaldehyde Metabolism and Its Impact on Human Health [DOI]
92. 92 Hoffman, 2015, Formaldehyde Crosslinking: A Tool for the Study of Chromatin Complexes [DOI]
93. 93 Adamović, D., Čepić, Z., Adamović, S., Stošić, M., Obrovski, B., Morača, S., and Miloradov, M.V. (2021). Occupational Exposure to Formaldehyde and Cancer Risk Assessment in an Anatomy Laboratory. Int. J. Environ. Res. Public Health, 18. [DOI]
94. 94 Kang, 2021, Formaldehyde Exposure and Leukemia Risk: A Comprehensive Review and Network-based Toxicogenomic Approach [DOI]
95. 95 Osman, 2017, Carvedilol Can Attenuate Histamine-Induced Paw Edema and Formaldehyde-Induced Arthritis in Rats without Risk of Gastric Irritation [DOI]
96. 96 Bernardini, 2022, Formaldehyde Toxicity Reports from In Vitro and In Vivo Studies: A Review and Updated Data [DOI]
97. 97 Nishikawa, 2021, A Comprehensive Review of Mechanistic Insights into Formaldehyde-induced Nasal Cavity Carcinogenicity [DOI]
98. 98 Andersen, 2019, Considerations for Refining the Risk Assessment Process for Formaldehyde: Results from an Interdisciplinary Workshop [DOI]
99. 99 Zhao, 2021, Formaldehyde-induced Hematopoietic Stem and Progenitor Cell Toxicity in Mouse Lung and Nose [DOI]
100. 100 Awad, J., and Jung, C. (2021). Evaluating the Indoor Air Quality after Renovation at the Greens in Dubai, United Arab Emirates. Buildings, 11. [DOI]
101. 101 WHO (2010). Guidelines for Indoor Air Quality: Selected Pollutants, World Health Organization Regional Office for Europe.
102. 102 Cerrejon, 2020, Selective Formaldehyde Detection at ppb in Indoor Air with a Portable Sensor [DOI]
103. 103 Mitsubayashi, 2008, A Bio-sniffer Stick with FALDH (formaldehyde dehydrogenase) for Convenient Analysis of Gaseous Formaldehyde [DOI]
104. 104 He, 2020, Ppb-level Formaldehyde Detection System Based on a 3.6 µm Interband Cascade Laser and Mode-locked Cavity Enhanced Absorption Spectroscopy with Self-calibration of the Locking Frequency [DOI]
105. 105 Peng, 2022, A CuO thin film type sensor via inkjet printing technology with high reproducibility for ppb-level formaldehyde detection [DOI]
106. 106 Protano, C., Antonucci, A., De Giorgi, A., Zanni, S., Mazzeo, E., Cammalleri, V., Fabiani, L., Mastrantonio, R., Muselli, M., and Mastrangeli, G. (2024). Exposure and Early Effect Biomarkers for Risk Assessment of Occupational Exposure to Formaldehyde: A Systematic Review. Sustainability, 16. [DOI]
107. 107 Ferreira, 2021, Insights on the Role of Acetaldehyde and Other Aldehydes in the Odour and Tactile Nasal Perception of Red Wine [DOI]
108. 108 Majchrowicz, 1970, Blood Concentrations of Acetaldehyde and Ethanol in Chronic Alcoholics [DOI]
109. 109 (2024, October 18). U.S. Environmental Protection Agency: Research Triangle Park, NC, USA, Available online: https://nepis.epa.gov/Exe/ZyNET.EXE?ZyActionL=Register&User=anonymous&Password=anonymous&Client=EPA&Init=1.
110. 110 Bauer, K., Garbe, D., and Surburg, H. (2001). Common Fragrance and Flavor Materials: Preparation, Properties and Uses, Wiley-VCH. [DOI]
111. 111 Belloche, 2022, Toward the Limits of Complexity of interstellar chemistry: Rotational spectroscopy and astronomical search for n-and i-butanal [DOI]
112. 112 Diacon, 2022, On the Ultrasound-assisted Preparation of Cu/SiO2 System as a Selective Catalyst for the Conversion of Biobutanol to Butanal [DOI]
113. 113 Chang, 2020, Deep-fried Flavor: Characteristics, Formation Mechanisms, and Influencing Factors [DOI]
114. 114 Rosati, 2007, Emissions from Cooking Microwave Popcorn [DOI]
115. 115 Yang, 2022, Characterization of the Key Aroma Compounds in Black Teas with Different Aroma Types by Using Gas Chromatography Electronic Nose, Gas Chromatography-Ion Mobility Spectrometry, and Odor Activity Value Analysis [DOI]
116. 116 Rizzo, 2020, Sensory Characterization of Specific Wood Smoke Aromas and their Contributions to Smoked Cheddar Cheese Flavor [DOI]
117. 117 Chen, C., Yuan, J., Yu, H., Lou, X., Wang, B., Xu, Z., and Tian, H. (2022). Cloning, Purification, and Characterization of Branched-chain α-keto Acid Decarboxylases from Lactococcus lactis Strains with Different 3-Methylbutanal Production Abilities. Food Biosci., 47. [DOI]
118. 118 Du, 2020, Key Aroma Compounds in Chinese Fried Food of Youtiao [DOI]
119. 119 Meng, 2021, Formation of 3-Methylbutanal and 3-Methylbutan-1-ol Recognized as Malty during Fermentation in Swiss Raclette-Type Cheese, Reconstituted Milk, and de Man, Rogosa, and Sharpe Broth [DOI]
120. 120 Yuan, C., Xu, C., Chen, L., Yang, J., Qiao, M., and Wu, Z. (2024). Effect of Different Cooking Methods on the Aroma and Taste of Chicken Broth. Molecules, 29. [DOI]
121. 121 Li, 2022, Biocontrol Potential of 1-Pentanal Emitted from Lactic Acid Bacteria Strains against Aspergillus flavus in Red Pepper (Capsicum annuum L.) [DOI]
122. 122 Frankel, 1983, Volatile lipid oxidation products [DOI]
123. 123 Cho, Y., Song, M., Kim, T.S., and Ryu, J.C. (2018). DNA Methylome Analysis of Saturated Aliphatic Aldehydes in Pulmonary Toxicity. Sci. Rep., 8. [DOI]
124. 124 Majchrzak, 2022, Understanding the Early-Stage Release of Volatile Organic Compounds from Rapeseed Oil During Deep-Frying of Tubers by Targeted and Omics-Inspired Approaches Using Ptr-Ms and Gas Chromatography [DOI]
125. 125 Kiefer, 2021, Volutrauma Increases Exhaled Pentanal in Rats: A Potential Breath Biomarker for Ventilator-Induced Lung Injury
126. 126 Ma, 2023, Recent Advances on Mulberry Volatile Flavor: A Review [DOI]
127. 127 Iregren, 2006, Acute Effects of Exposure to Hexanal Vapors in Humans [DOI]
128. 128 Lu, X., Gao, Y., Wang, K., Sun, S.M., Liu, Z., Yan, P., Feng, J.R., Li, Q.S., Li, L.W., and Wang, D.J. (2022). Dwarf Interstocks Improve Aroma Quality of ‘Huahong’ Apple (Malus × domestica). Agriculture, 12. [DOI]
129. 129 Ma, 2021, Effects of Shading on the Synthesis of Volatile Organic Compounds in ‘Marselan’ grape berries (Vitis vinifera L.) [DOI]
130. 130 Kafkas, 2022, Volatile Compositions of Strawberry Fruit during Shelf Life Using Pre and Postharvest Hexanal Treatment
131. 131 Furia, T.E., and Bellanca, N. (1975). Fenaroli’s Handbook of Flavor Ingredients, CRC Press, Inc.
132. 132 Thomas, 2023, Comparison of Fragrance and Flavor Components in Non-psilocybin and Psilocybin Mushrooms Using Vacuum-assisted Headspace High-capacity Solid-phase Microextraction and Gas Chromatography–mass Spectrometry [DOI]
133. 133 Aisala, 2019, Odor-contributing Volatile Compounds of Wild Edible Nordic Mushrooms Analyzed with HS–SPME–GC–MS and HS–SPME–GC–O/FID [DOI]
134. 134 Ashitha, 2020, Effect of Pre-harvest and Post-harvest Hexanal Treatments on Fruits and Vegetables: A Review
135. 135 Paliyath, G., and Padmanabhan, P. (2019). Chapter 4: Preharvest and Postharvest Technologies Based on Hexanal: An Overview. Postharvest Biology and Nanotechnology, John Wiley & Sons, Inc.. [1st ed.]. [DOI]
136. 136 Kaur, 2020, Pre-Harvest Application of Hexanal Formulations for Improving Post-Harvest Life and Quality of Mango (Mangifera indica L.) Cv. Dashehari [DOI]
137. 137 Eryol, 2023, Postharvest Hexanal Application Delays Senescence and Maintains Quality in Persimmon Fruit During Low-temperature Storage [DOI]
138. 138 Dhakshinamoorthy, 2020, Hexanal vapor induced resistance against major postharvest pathogens of banana (Musa acuminata L.) [DOI]
139. 139 Öz, A.T., and Ali, A. (2023). Retaining Overall Quality of Fresh Figs by Postharvest Hexanal Vapor Treatment during Cold Storage. Postharvest Biol. Technol., 205. [DOI]
140. 140 Cho, 2016, MicroRNA Response of Inhalation Exposure to Hexanal in Lung Tissues from Fischer 344 Rats [DOI]
141. 141 Corradi, 2003, Aldehydes in Exhaled Breath Condensate of Patients with Chronic Obstructive Pulmonary Disease [DOI]
142. 142 Phillips, 2006, Prediction of Breast Cancer Using Volatile Biomarkers in the Breath [DOI]
143. 143 Ulanowska, 2011, The Application of Statistical Methods Using VOCs to Identify Patients with Lung Cancer [DOI]
144. 144 Zhang, 2023, The Regulation of Key Flavor of Traditional Fermented Food by Microbial Metabolism: A Review [DOI]
145. 145 Yanru, X.U., Qingzheng, W.A.N.G., Guizhang, G.U., Zhang, J., and Dalun, X.U. Study on the Function of Pepper Essential Oil in Endowing Flavor of Pepper-Salt Baked Shrimp. Shipin Gongye Ke-Ji.
146. 146 Sacchetti, 2021, Wheat Classification According to Its Origin by an Implemented Volatile Organic Compounds Analysis [DOI]
147. 147 Basile, 2023, Ancient Wheat as Promising Nutraceuticals for the Prevention of Chronic and Degenerative Diseases [DOI]
148. 148 2023, Identification of Volatile Compounds in Salep (Serapias vomeracea) Tubers and Effects of Harvest Time and Drying Method on Composition Variation [DOI]
149. 149 Catalano, 2020, COVID-19: Could Irisin Become the Handyman Myokine of the 21st Century? [DOI]
150. 150 Zhu, 2022, Detection of Covid-19 through a Heptanal Biomarker Using Transition Metal Doped Graphene [DOI]
151. 151 Hu, 2020, 13-Plex UHPLC–MS/MS Analysis of Hexanal and Heptanal Using Multiplex Tags Chemical isotope Labeling Technology [DOI]
152. 152 Aparisi, 2023, Determination of Hexanal and Heptanal in Saliva Samples by an Adapted Magnetic Headspace Adsorptive Microextraction for Diagnosis of Lung Cancer [DOI]
153. 153 Reineccius, G. (1994). Flavoring Ingredients Classified As GRAS By the Flavor Extract Manufacturers Association. Source Book of Flavors, Springer. [DOI]
154. 154 Liu, 2012, Isolation and Biological Activities of Decanal, Linalool, Valencene, and Octanal from Sweet Orange Oil [DOI]
155. 155 Ghosh, A., Ghosh, B., Parihar, N., Ilaweibaphyrnai, M., Panda, S.R., Alexander, A., Chella, N., Murty, U.S.N., Naidu, V.G.M., and Jagadeesh, K.G. (2022). Nutraceutical Prospects of Houttuynia cordata against the Infectious Viruses. Food Biosci., 50. [DOI]
156. 156 Zhou, 2014, Antifungal Activity of Citral, Octanal and α-Terpineol against Geotrichum citri-aurantii [DOI]
157. 157 Duan, B., Zhang, Y., Feng, Z., Liu, Z., and Tao, N. (2024). Octanal Enhances Disease Resistance in Postharvest Citrus Fruit by the Biosynthesis and Metabolism of Aromatic Amino Acids. Pestic. Biochem. Physiol., 200. [DOI]
158. 158 Song, 2014, Octanal-induced Inflammatory Responses in Cells Relevant for Lung Toxicity: Expression and Release of Cytokines in A549 Human Alveolar Cells [DOI]
159. 159 Noordraven, 2021, Flavour stability of sterilised chickpeas stored in pouches [DOI]
160. 160 Takakura, 2014, Characterization of the Key Aroma Compounds in Pork Soup Stock by Using an Aroma Extract Dilution Analysis [DOI]
161. 161 Wettasinghe, 2001, Volatile Flavour Composition of Cooked By-product Blends of Chicken, Beef and Pork: A Quantitative GC–MS Investigation [DOI]
162. 162 Chang, 2021, Characterization of the Physicochemical Changes and Volatile Compound Fingerprinting during the Chicken Sugar-smoking Process [DOI]
163. 163 Feng, 2018, Differentiation between Flavors of Sweet Orange (Citrus sinensis) and Mandarin (Citrus reticulata) [DOI]
164. 164 Lan-Phi, N.T. (2010). Gas chromatography-–olfactometry and aroma--active components in citrus essential oils. Citrus Essential Oils: Flavor and Fragrance, Wiley. [DOI]
165. 165 Boukouvalas, 2014, Streamlined Biomimetic Synthesis of Paracaseolide A via Aerobic Oxidation of a 2-Silyloxyfuran [DOI]
166. 166 Varghese, C.P., Murugaiyah, V., Parasuraman, S., and Christina, A.J.M. (2024). Bioactive Phytoconstituents and Biological Activities of Polygonum minus Huds. Bioactive Compounds in the Storage Organs of Plants, Springer. [DOI]
167. 167 Perkins, 2023, The volatile chemistry of orchid pollination [DOI]
168. 168 Mishor, 2021, Sniffing the Human Body Volatile Hexadecanal Blocks Aggression in Men but Triggers Aggression in Women [DOI]
169. 169 Jiang, K., Huang, C., Liu, F., Zheng, J., Ou, J., Zhao, D., and Ou, S. (2022). Origin and Fate of Acrolein in Foods. Foods, 11. [DOI]
170. 170 IARC (International Agency for Research on Cancer) (1994). Some Industrial Chemicals. IARC Monographs on the Evaluation of Carcinogenic Risk for Chemicals to Humans.
171. 171 Daniali, 2016, Acrylamide Formation in Vegetable Oils and Animal Fats during Heat Treatment [DOI]
172. 172 Song, 2022, Acrylamide Formation and Aroma Evaluation of Fried Pepper Sauce under Different Exogenous Maillard Reaction Conditions [DOI]
173. 173 Ambaw, 2018, Acrolein-mediated Neuronal Cell Death and alpha-Synuclein Aggregation: Implications for Parkinson’s Disease [DOI]
174. 174 Arumugam, 2017, Neutrophil Extracellular Traps in Acrolein Promoted Hepatic Ischemia Reperfusion Injury: Therapeutic Potential of NOX2 and P38MAPK Inhibitors [DOI]
175. 175 Burcham, 2017, Acrolein and Human Disease: Untangling the Knotty Exposure Scenarios Accompanying Several Diverse Disorders [DOI]
176. 176 Hikisz, P., and Jacenik, D. (2023). The Tobacco Smoke Component, Acrolein, as a Major Culprit in Lung Diseases and Respiratory Cancers: Molecular Mechanisms of Acrolein Cytotoxic Activity. Cells, 12. [DOI]
177. 177 Zhou, 2023, Acrolein: Formation, health hazards and its controlling by dietary polyphenols
178. 178 Chang, X., Wang, Y., Zheng, B., Chen, Y., Xie, J., Song, Y., Ding, X., Hu, X., Hu, X., and Yu, Q. (2022). The Role of Acrolein in Neurodegenerative Diseases and Its Protective Strategy. Foods, 11. [DOI]
179. 179 Guo, 2023, DNA damage in human oral cells induced by use of e-cigarettes [DOI]
180. 180 Li, 2022, Carcinogenic Components of Tobacco and Tobacco Smoke: A 2022 Update [DOI]
181. 181 Weerawatanakorn, 2015, Reactivity and Stability of Selected Flavor Compounds [DOI]
182. 182 Paoli, 2023, A Fast and Reliable Method to Quantify Neral and Geranial (Citral) in Essential Oils using 1H NMR Spectroscopy [DOI]
183. 183 Lu, 2018, Preparation, Characterization, and Antimicrobial Activity of Nanoemulsions Incorporating Citral Essential Oil [DOI]
184. 184 Tak, 2016, Metabolism of Citral, the Major Constituent of Lemongrass Oil, in the Cabbage Looper, Trichoplusia ni, and Effects of Enzyme Inhibitors on Toxicity and Metabolism [DOI]
185. 185 Nishijima, 2014, Citral: A Monoterpene with Prophylactic and Therapeutic Anti-Nociceptive Effects in Experimental Models of Acute and Chronic Pain [DOI]
186. 186 Bailly, 2020, Targets and Pathways Involved in the Antitumor Activity of Citral and its Stereo-isomers [DOI]
187. 187 Zheng, Y., Shang, Y., Li, M., Li, Y., and Ouyang, W. (2021). Antifungal Activities of cis-trans Citral Isomers against Trichophyton rubrum with ERG6 as a Potential Target. Molecules, 26. [DOI]
188. 188 Song, 2023, Plant Secondary Metabolite Citral Interferes with Phytophthora Capsici Virulence by Manipulating the Expression of Effector Genes [DOI]
189. 189 Cramer, 1976, Estimation of Toxic Hazard—A Decision Tree Approach [DOI]
190. 190 Kroes, 2007, Application of the Threshold of Toxicological Concern (TTC) to the Safety Evaluation of Cosmetic Ingredients [DOI]
191. 191 Api, 2022, RIFM fragrance Ingredient Safety Assessment, 4-Tricyclodecylidene Butanal, CAS Registry Number 30168-23-1 [DOI]
192. 192 Api, 2022, RIFM Fragrance Ingredient Safety Assessment, β,4-Dimethylcyclohex-3-ene-1-propan-1-al, CAS Registry Number 6784-13-0 [DOI]
193. 193 Api, 2022, RIFM Fragrance Ingredient Safety Assessment, 1-Methyl-4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde, CAS registry number 52475-86-2 [DOI]
194. 194 Api, 2021, RIFM Fragrance Ingredient Safety Assessment, α,α,6,6-Tetramethylbicyclo[3.1.1]hept-2-ene-2-propionaldehyde, CAS Registry Number 33885-52-8 [DOI]
195. 195 Yu, 2020, Aroma Perceptual Interactions of Benzaldehyde, Furfural, and Vanillin and their Effects on the Descriptor Intensities of Huangjiu [DOI]
196. 196 Ramachanderan, 2019, Lily-of-the-valley fragrances [DOI]
197. 197 Ohrmann, 2023, On the Structure–Odor Correlation of Muguet Aldehydes: Synthesis of 3-(4′-Isobutyl-2′-methylphenyl)propanal (Nympheal) and Four Novel Derivatives from a Hagemann’s Ester [DOI]
198. 198 Jordi, 2018, Crossing the Boundaries between Marine and Muguet: Discovery of Unusual Lily-of-the-Valley Odorants Devoid of Aldehyde Functions [DOI]
199. 199 Chung, F.Y., Lin, Y.Z., Huang, C.R., Huang, K.W., and Chen, Y.F. (2024). Crosslinking Kiwifruit-derived DNA with Natural Aromatic Aldehydes Generates Membranolytic Antibacterial Nanogels. Int. J. Biol. Macromol., 255. [DOI]
200. 200 Laue, 2017, p-Alkyl-benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes with Rat Testicular Toxicity—Studies Leading to the Design of a Safer New Fragrance Chemical [DOI]
201. 201 Opgrande, J.L., Brown, E.E., Hesser, M., and Andrews, J. (2001). Benzaldehyde. Kirk-Othmer Encyclopedia of Chemical Technology, John Wiley & Sons. [DOI]
202. 202 Verma, 2023, A Multi Responsive Phosphonic Acid Based Fluorescent Sensor for Sensing Fe3+, Benzaldehyde and Antibiotics [DOI]
203. 203 Pepe, R.C., Wenninger, J.A., and McEwen, G.N. (2002). , International Cosmetic Ingredient Dictionary and Handbook, CTFA. [9th ed.].
204. 204 Jermnak, U., Ngernmeesri, P., Yurayart, C., Poapolathep, A., Udomkusonsri, P., Poapolathep, S., and Phaochoosak, N. (2023). A New Benzaldehyde Derivative Exhibits Antiaflatoxigenic Activity against Aspergillus flavus. J. Fungi, 9. [DOI]
205. 205 Andersen, 2006, Final Report on the Safety Assessment of Benzaldehyde [DOI]
206. 206 Neto, L.J.L., Ramos, A.G.B., Freitas, T.S., Barbosa, C., de Sousa Júnior, D.L., Siyadatpanah, A., Nejat, M., Wilairatana, P., Coutinho, H.D.M., and da Cunha, F.A.B. (2021). Evaluation of Benzaldehyde as an Antibiotic Modulator and Its Toxic Effect against Drosophila melanogaster. Molecules, 26. [DOI]
207. 207 Kim, 2022, Benzaldehyde Use to Protect Seeds from Foodborne Fungal Pathogens
208. 208 Writer, C.I.R. (2024, October 18). Safety Assessment of Benzaldehyde as Used in Cosmetics. Available online: www.cir-safety.org.
209. 209 Yong, K.J., Wu, T.Y., Lee, C.B.T.L., Lee, Z.J., Liu, Q., Jahim, J.M.D., Zhou, Q., and Zhang, L. (2022). Furfural Production from Biomass Residues: Current Technologies, Challenges and Future Prospects. Biomass Bioenergy, 161. [DOI]
210. 210 Shen, 2022, Analysis of the Evolution of Potential and Free Furfural Compounds in the Production Chain of Infant Formula and Risk Assessment [DOI]
211. 211 Mehrotra, 2022, A Quick and Simple Paper-based Method for Detection of Furfural and 5-Hydroxymethylfurfural in Beverages and Fruit Juices [DOI]
212. 212 Bazrafshan, 2023, Synthesis of Magnesium Oxide Nanoparticles and its Application for Photocatalytic Removal of Furfural from Aqueous Media: Optimization Using Response Surface Methodology [DOI]
213. 213 Wang, 2023, Discovery of New Strains for Furfural Degradation Using Adaptive Laboratory Evolution in Saccharomyces cerevisiae [DOI]
214. 214 Walton, 2003, Vanillin [DOI]
215. 215 Jiang, W., Chen, X., Feng, Y., Sun, J., Jiang, Y., Zhang, W., Xin, F., and Jiang, M. (2023). Current Status, Challenges, and Prospects for the Biological Production of Vanillin. Fermentation, 9. [DOI]
216. 216 Banerjee, 2019, Vanillin Biotechnology: The Perspectives and Future [DOI]
217. 217 Xu, 2024, Advances in the Vanillin Synthesis and Biotransformation: A Review [DOI]
218. 218 Xu, L., Liaqat, F., Khazi, M.I., Sun, J., and Zhu, D. (2024). Natural Deep Eutectic Solvents-based Green Extraction of Vanillin: Optimization, Purification, and Bioactivity Assessment. Front. Nutr., 10. [DOI]
219. 219 Moore, 2020, Key Odorants from Daldinia childiae [DOI]
220. 220 Xin, 2023, Antimicrobial and Biofilm Inhibition Effects of p-Anisaldehyde against Vibrio parahaemolyticus [DOI]
221. 221 Adewunmi, Y., Namjilsuren, S., Walker, W.D., Amato, D.N., Amato, D.V., Mavrodi, O.V., Patton, D.L., and Mavrodi, D.V. (2020). Antimicrobial Activity of, and Cellular Pathways Targeted by, p-Anisaldehyde and Epigallocatechin Gallate in the Opportunistic Human Pathogen Pseudomonas aeruginosa. Appl. Environ. Microbiol., 86. [DOI]
222. 222 Che, 2019, p-Anisaldehyde Exerts its Antifungal Activity against Penicillium digitatum and Penicillium italicum by Disrupting the Cell Wall Integrity and Membrane Permeability [DOI]
223. 223 Xin, 2024, Antifungal Mechanism of p-Anisaldehyde against Aspergillus flavus Based on Transcriptome Analysis [DOI]
224. 224 Shreaz, 2011, Exposure of Candida to p-Anisaldehyde Inhibits its Growth and Ergosterol Biosynthesis [DOI]
225. 225 Chen, 2016, Efficacy of a Combination of Nisin and p-Anisaldehyde against Listeria monocytogenes [DOI]
226. 226 Shi, 2017, Synergistic Antimicrobial Effects of Nisin and p-Anisaldehyde on Staphylococcus aureus in Pasteurized Milk [DOI]
227. 227 Kong, 2023, Role of p-Anisaldehyde in the Differentiation of C2C12 Myoblasts [DOI]
228. 228 Younes, 2021, Scientific Opinion on Flavouring Group Evaluation 414 (FGE. 414): 2-hydroxy-4-methoxybenzaldehyde
229. 229 Harohally, 2017, Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2-Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes [DOI]
230. 230 Rathi, 2017, 2-Hydroxy-4-methoxybenzaldehyde, an Astounding Food Flavoring Metabolite: A Review
231. 231 Gangopadhyay, 2021, Evaluation of Growth Response for Mass Production and Accumulation of 2-Hydroxy-4-methoxybenzaldehyde in Endangered Hemidesmus indicus by an Aeroponic System [DOI]
232. 232 Rodrigues, 2021, Adventitious Root Cultures of Decalepis salicifolia for the Production of 2-Hydroxy-4-methoxybenzaldehyde, a Vanillin Isomer Flavor Metabolite [DOI]
233. 233 Andati, R.E., Omolo, M.O., and Ndiege, I.O. (2021). Ovicidal Activity of 2-Hydroxy-4-Methoxybenzaldehyde, Derivatives and Structural Analogues on Anopheles gambiae eggs. bioRxiv, 2021. [DOI]
234. 234 Mishra, 2022, Establishment of In Vitro Cell Suspension Culture, Kinetics of Cell Growth, pH, Nutrient Uptake and Production of 2-Hydroxy-4-methoxybenzaldehyde from the Germinated Root of Decalepis hamiltonii Wight & Arn.-An Endangered Plant
235. 235 Arunachalam, K., Ravi, J., Tian, X., Shunmugiah, K.P., Shanmugaraj, G., and Shi, C. (2023). Antibacterial Activity of 2-Hydroxy-4-methoxybenzaldehyde and its Possible Mechanism against Staphylococcus aureus. J. Appl. Microbiol., 134. [DOI]
236. 236 Li, 2020, 2-Hydroxy-4-methoxybenzaldehyde Inhibits the Growth of Aspergillus flavus via Damaging Cell Wall, Cell Membrane, Manipulating Respiration thus Creating a Promising Antifungal Effect on Corn Kernels [DOI]
237. 237 Li, Q., Wang, C., Xiao, H., Zhang, Y., and Xie, Y. (2024). 2-Hydroxy-4-methoxybenzaldehyde, a More Effective Antifungal Aroma than Vanillin and its Derivatives against Fusarium graminearum, Destroys Cell Membranes, Inhibits DON Biosynthesis, and Performs a Promising Antifungal Effect on Wheat Grains. Front. Microbiol., 15. [DOI]
238. 238 Ravindran, D., Rajaiah, A., Swasthika, R., Balu, P., Gopalakrishnan, A., Krishna Kumar, A.K., Muthusamy, S., Malayandi, J., Durairaj, R., and Arumugam, V.R. Evaluation of Bcr/cflA Targeted Efflux Inhibitory Potential of 2-Hydroxy-4-Methoxybenzaldehyde against Proteus mirabilis. Ind. J. Microbiol., in press.
239. 239 Durgam, 2023, 2-Hydroxy-4-methoxy benzaldehyde from Hemidesmus indicus Root Extract Suppresses Toll-like rRceptor2-mediated Migration and Invasive Mechanisms in Rheumatoid Arthritis [DOI]
240. 240 Zviely, 2012, The Phenylpropanals–Floral Aromatic Aldehydes
241. 241 Jin, 2023, Stereocomplementary Synthesis of β-Aryl Propanamines by Enzymatic Dynamic Kinetic Resolution-Reductive Amination [DOI]
242. 242 Mosciano, 1994, Organoleptic Characteristics of Flavor Materials
243. 243 Lozynskyi, 2022, 3-Phenylpropanal and Citral in the Multicomponent Synthesis of Novel Thiopyrano[2,3-d]thiazoles [DOI]
244. 244 Avila, E., Nixarlidis, C., and Shon, Y.S. (2023). Water-Soluble Pd Nanoparticles for the Anti-Markovnikov Oxidation of Allyl Benzene in Water. Nanomaterials, 13. [DOI]
245. 245 Gorbachev, 2022, Synthesis of New Morphinan Opioids by TBADT-Catalyzed Photochemical Functionalization at the Carbon Skeleton [DOI]
246. 246 Hareng, 2023, Towards the Mechanism of Spermatotoxicity of p-tert-Butyl-alpha-methylhydrocinnamic Aldehyde: Inhibition of Late Stage Ex-Vivo Spermatogenesis in Rat Seminiferous Tubule Cultures by para-tert-Butyl-Benzoic Acid [DOI]
247. 247 ECHA (2024, June 18). European Chemicals Agency: Summary of Classification and Labeling, 3-(p-Cumenyl)propionaldehyde. Available online: https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/84780.
248. 248 (2024, June 18). ECHA Substance Information. Available online: https://echa.europa.eu/substance-information/-/substanceinfo/100.038.182.
249. 249 Movalli, 2023, High Resolution Mass Spectrometric Suspect Screening, Wide-scope Target Analysis of Emerging Contaminants and Determination of Legacy Pollutants in Adult Black-tailed Godwit Limosa limosa limosa in the Netherlands–A Pilot Study [DOI]
250. 250 Goeke, A., Kraft, P., Laue, H., Zou, Y., and Voirol, F. (2014). Int. Pat. Appl. (WO 2014180945 A1).
251. 251 Goeke, 2018, Discovery of Nympheal: The Definitive Muguet Aldehyde
252. 252 West, 1948, Synthetic perfumes
253. 253 Yokowo, 1981, Optical Activation of Some Perfume of Chiral Aldehydes via Enamines [DOI]
254. 254 Beghetto, 2012, Asymmetric Catalysis in Fragrance Chemistry: A New Catalytic Approach to Non Racemic Cyclamen-aldehyde
255. 255 Natsch, 2021, A Species Specific Metabolism Leading to Male Rat Reprotoxicity of Cyclamen Aldehyde: In Vivo and In Vitro Evaluation [DOI]
256. 256 (2024, June 10). Givaudan Health and Nutrition Hub. Available online: https://healthnutritionhub.givaudan.com/?gad_source=1&gclid=CjwKCAjw68K4BhAuEiwAylp3khI7wkT_6bkOixr83NdfZ-HGuL8YRlhfb_ORS16-6rgB_UHtxRs7nRoCQkUQAvD_BwE.
257. 257 (2024, June 10). Fragrance Ingredients Compendium. Available online: https://www.iff.com/portfolio/products/fragrance-ingredients/online-compendium/.
258. 258 Beghetto, 2015, A Practical, Enantioselective Synthesis of the Fragrances Canthoxal and Silvial®, and Evaluation of their Olfactory Activity [DOI]
259. 259 Gil, 2018, The Composition of Nonbeverage Alcohols Consumed in Russia in 2015–2017 [DOI]
260. 260 Scherer, 2017, Human Metabolism and Excretion Kinetics of the Fragrance Lysmeral after a Single Oral Dosage [DOI]
261. 261 Bernauer, U., Bodin, L., Celleno, L., Chaudhry, Q., Coenraads, P.J., Dusinska, M., Ezendam, J., Gaffet, E., Galli, C.L., and Granum, B. (2024, October 18). SCCS Preliminary OPINION ON the Safety of Butylphenyl Methylpropional (p-BMHCA) in Cosmetic Products”-Submission II, Ref SCCS/1591/17-Preliminary Version. 2017. hal-01669154. Available online: https://www.academia.edu/68263682/SCCS_preliminary_OPINION_ON_the_safety_of_Butylphenyl_methylpropional_p_BMHCA_in_cosmetic_products_Submission_II_ref_CCS_1591_17_Preliminary_version.
262. 262 Armanino, 2020, What’s Hot, What’s Not: The Trends of the Past 20 Years in the Chemistry of Odorants [DOI]
263. 263 de Sá, L.D.M. (2024, October 18). Farmácia 5 de Outubro, Porto e Serviços Farmacêuticos do Hospital CUF, Porto. Available online: https://sigarra.up.pt/ffup/pt/PUB_GERAL.PUB_VIEW?pi_pub_base_id=588952.
264. 264 (2024, October 18). Commission Regulation (EU) 2021/1902 of 29 October 2021 Amending Annexes II, III and V to Regulation (EC) No 1223/2009 of the European Parliament and of the Council as Regards the Use in Cosmetic Products of Certain Substances Classified as Carcinogenic. Available online: https://eur-lex.europa.eu/eli/reg/2021/1902/oj.
265. 265 (2024, October 18). Commission Regulation (EU) 2017/1410 of 2 August 2017 Amending Annexes II and III to Regulation (EC) No 1223/2009 of the European Parliament and of the Council on Cosmetic Products. Available online: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32017R1410.
266. 266 UNION, P. (2024, June 18). Regulation (EC) No 1223/2009 of the European Parliament and of the Council. Available online: https://health.ec.europa.eu/system/files/2016-11/cosmetic_1223_2009_regulation_en_0.pdf.
267. 267 European Commission (2024, June 18). Commission Delegated Regulation (EU) 2020/1182 of 19 May 2020 Amending, for the Purposes of Its Adaptation to Technical and Scientific Progress, Part 3 of Annex VI to Regulation (EC) no 1272/2008 of the European Parliament and of the Council on Classification, Labelling and Packaging of Substances and Mixtures. Available online: https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX%3A32020R1182.
268. 268 Soriano, 2023, Ironing water: An under-recognized source of contact allergens [DOI]
269. 269 (2024, October 18). Da Lycia a Nivea, Passando per Infasil e Palmolive, Ecco Tutti i Prodotti Richiamati per la Presenza di Sostanza Vietata (LISTA AGGIORNATA). Available online: https://www.greenme.it/lifestyle/sai-cosa-compri/da-lycia-a-nivea-passando-per-infasil-e-palmolive-ecco-tutti-i-prodotti-richiamati-per-la-presenza-di-sostanza-vietata-lista-aggiornata/.
270. 270 (2024, October 18). LIlial, Nuovi Ritiri: L’Elenco Aggiornato con Oltre 130 Prodotti Nocivi Bloccati. Available online: https://ilsalvagente.it/2023/10/15/lilial-nuovi-ritiri-lelenco-aggiornato-con-oltre-130-prodotti-nocivi-bloccati/.
271. 271 (2024, June 18). Safety Gate: The EU Rapid Alert System for Dangerous Non-Food Products. Available online: https://ec.europa.eu/safety-gate-alerts/screen/search.
272. 272 Pigłowski, M. (2023). Notifications in European Rapid Alert system for dangerous products (RAPEX). Safety and Reliability of Systems and Processes. Summer Safety and Reliability Seminar 2023, Gdynia Maritime University. [DOI]
273. 273 Ferreira, M., Matos, A., Couras, A., Marto, J., and Ribeiro, H. (2022). Overview of Cosmetic Regulatory Frameworks around the World. Cosmetics, 9. [DOI]
274. 274 Canada.ca (2024, June 18). Cosmetic Ingredient Hotlist: Prohibited and Restricted Ingredients. Available online: https://www.canada.ca/en/health-canada/services/consumer-product-safety/cosmetics/cosmetic-ingredient-hotlist-prohibited-restricted-ingredients.html.
275. 275 U.S. Food & Drug Administration (2024, June 18). Prohibited & Restricted Ingredients in Cosmetics, Available online: https://www.fda.gov/cosmetics/cosmetics-laws-regulations/prohibited-restricted-ingredients-cosmetics.
276. 276 U.S. Food & Drug Administration (2024, June 18). Product Testing of Cosmetics, Available online: https://www.fda.gov/cosmetics/cosmetics-science-research/product-testing-cosmetics.
277. 277 Cosmetic Ingredient Review (2024, June 18). About the Cosmetic Ingredient Review. Available online: https://www.cir-safety.org/about.
278. 278 Sinicropi, M.S., Iacopetta, D., Ceramella, J., Catalano, A., Mariconda, A., Pellegrino, M., Saturnino, C., Longo, P., and Aquaro, S. (2022). Triclosan: A Small Molecule with Controversial Roles. Antibiotics, 11. [DOI]
279. 279 ECHA Disseminated Dossier (2024, March 07). 2-(4-tert-Butylbenzyl)propionaldehyde. Available online: https://echa.europa.eu/it/substance-information/-/substanceinfo/100.001.173.
280. 280 ECHA (2024, June 18). Substance Infocard: 2-(4-tert-Butylbenzyl)propionaldehyde. Available online: https://echa.europa.eu/substance-information/-/substanceinfo/100.001.173.
281. 281 ECHA (2024, June 18). European Chemicals Agency: REACH Registration Dossier, 3-(4-tert-Butylphenyl)-2-Methylpropanal. Available online: http://echa.europa.eu/registration-dossier/-/registered-dossier/13572.
282. 282 Laue, 2020, Benzoyl-CoA Conjugate Accumulation as an Initiating Event for Male Reprotoxic Effects in the Rat? Structure–Activity Analysis, Species Specificity, and In vivo Relevance [DOI]
283. 283 Hunter, 1965, Studies on the Oral Toxicity of p-tert-Butyl Benzoic Acid in Rats [DOI]
284. 284 Whorton, 1981, Testicular Function of Men Occupationally exposed to para-tertiary Butyl Benzoic Acid [DOI]
285. 285 Bernard, A. (2022). Dermal exposure to hazardous chemicals in baby diapers: A re-evaluation of the quantitative health risk assessment conducted by the French Agency for Food, Environmental and Occupational Health and Safety (ANSES). Int. J. Environ. Res. Public Health, 19. [DOI]
286. 286 Api, 2020, RIFM Fragrance Ingredient Safety Assessment, p-t-butyl-α-methylhydrocinnamic aldehyde, CAS Registry Number 80-54-6 [DOI]
287. 287 Jablonská, E., Míchal, Z., Křížkovská, B., Strnad, O., Tran, V.N., Žalmanová, T., Petr, J., Lipov, J., and Viktorová, J. (2023). Toxicological Investigation of Lilial. Sci. Rep., 13. [DOI]
288. 288 Ceramella, J., Iacopetta, D., Franchini, A., De Luca, M., Saturnino, C., Andreu, I., Sinicropi, M.S., and Catalano, A. (2022). A Look at the Importance of Chirality in Drug Activity: Some Significative Examples. Appl. Sci., 12. [DOI]
289. 289 Murawski, 2020, Metabolites of the Fragrance 2-(4-tert-butylbenzyl)propionaldehyde (Lysmeral) in Urine of Children and Adolescents in Germany—Human Biomonitoring Results of the German Environmental Survey 2014–2017 (GerES V) [DOI]
290. 290 Fichter, S.C., Groth, K., Fiedler, N., Kolossa-Gehring, M., Dębiak, M., and INGER Study Group (2022). Lysmeral Exposure in Children and Adolescences Participating in the German Environmental Survey (2012–2015): Integrating Sex/Gender into Analysis. Int. J. Environ. Res. Public Health, 19. [DOI]
291. 291 Yan, 2023, Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action [DOI]
292. 292 Song, 2024, Floralozone Regulates MiR-7a-5p Expression through AMPKα2 Activation to Improve Cognitive Dysfunction in Vascular Dementia [DOI]
293. 293 Huang, 2021, Floralozone Protects Endothelial Function in Atherosclerosis by Ameliorating NHE1 [DOI]
294. 294 Xu, 2023, A New Potential Strategy for Treatment of Ischemic Stroke: Targeting TRPM2–NMDAR Association [DOI]
295. 295 Weng, 2024, The biological fate, health benefits and novel delivery strategies for cinnamaldehyde [DOI]
296. 296 Nussbaum, 2017, Modern Treatment Approaches in Psychoses. Pharmacogenetic, neuroimagistic and Clinical Implications
297. 297 Khare, 2016, Cinnamaldehyde Supplementation Prevents Fasting-induced Hyperphagia, Lipid Accumulation, and Inflammation in High-fat Diet-fed Mice [DOI]
298. 298 Altun, 2016, Cinnamaldehyde Is an Effective Anti-inflammatory Agent for Treatment of Allergic Rhinitis in a Rat Model [DOI]
299. 299 Nakhaee, 2024, Cinnamon and Cognitive Function: A Systematic Review of Preclinical and Clinical Studies [DOI]
300. 300 He, Z., Huang, Z., Jiang, W., and Zhou, W. (2019). Antimicrobial Activity of Cinnamaldehyde on Streptococcus mutans Biofilms. Front. Microbiol., 10. [DOI]
301. 301 Iacopetta, D., Ceramella, J., Catalano, A., D’Amato, A., Lauria, G., Saturnino, C., Andreu, I., Longo, P., and Sinicropi, M.S. (2023). Diarylureas: New Promising Small Molecules against Streptococcus mutans for the Treatment of Dental Caries. Antibiotics, 12. [DOI]
302. 302 Banerjee, 2023, Anticancer Potential and Molecular Mechanisms of Cinnamaldehyde and Its Congeners Present in the Cinnamon Plant [DOI]
303. 303 Vezzani, 2023, SARS-CoV-2 Infection as a Model to Study the Effect of Cinnamaldehyde as Adjuvant Therapy for Viral Pneumonia [DOI]
304. 304 Catalano, A., Iacopetta, D., Ceramella, J., Maio, A.C., Basile, G., Giuzio, F., Bonomo, M.G., Aquaro, S., Walsh, T.J., and Sinicropi, M.S. (2022). Are Nutraceuticals Effective in COVID-19 and Post-COVID Prevention and Treatment?. Foods, 11. [DOI]
305. 305 Guo, X.R., Zhang, X.G., Wang, G.S., Wang, J., Liu, X.J., and Deng, J.H. (2024). Effect of Cinnamaldehyde on Systemic Candida albicans Infection in Mice. Chin. J. Integr. Med., in press. [DOI]
306. 306 Pereira, W., Pereira, C., Assunção, R., da Silva, I., Rego, F., Alves, L., Santos, J., Nogueira, F., Zagmignan, A., and Thomsen, T. (2021). New Insights into the Antimicrobial Action of Cinnamaldehyde towards Escherichia coli and Its Effects on Intestinal Colonization of Mice. Biomolecules, 11. [DOI]
307. 307 Topa, S.H., Palombo, E.A., Kingshott, P., and Blackall, L.L. (2020). Activity of Cinnamaldehyde on Quorum Sensing and Biofilm Susceptibility to Antibiotics in Pseudomonas aeruginosa. Microorganisms, 8. [DOI]
308. 308 Usai, F., and Di Sotto, A. (2023). Trans-cinnamaldehyde as a Novel Candidate to Overcome Bacterial Resistance: An Overview of In Vitro Studies. Antibiotics, 12. [DOI]
309. 309 Catalano, A., Iacopetta, D., Ceramella, J., Pellegrino, M., Giuzio, F., Marra, M., Rosano, C., Saturnino, C., Sinicropi, M.S., and Aquaro, S. (2023). Antibiotic-Resistant ESKAPE Pathogens and COVID-19: The Pandemic beyond the Pandemic. Viruses, 15. [DOI]
310. 310 Friedman, 2017, Chemistry, Antimicrobial Mechanisms, and Antibiotic Activities of Cinnamaldehyde against Pathogenic Bacteria in Animal Feeds and Human Foods [DOI]
311. 311 Shreaz, 2016, Cinnamaldehyde and its derivatives, a novel class of antifungal agents [DOI]
312. 312 Honma, 2021, In Vivo and in Vitro Mutagenicity of Perillaldehyde and Cinnamaldehyde [DOI]
313. 313 Alves, D.D.N., Martins, R.X., Ferreira, E.D.S., Alves, A.F., Andrade, J.C.D., Batista, T.M., Lazarini, J.G., Amorim, L.S., Rosalen, P.M., and Castro, R.D.D. (2021). Toxicological Parameters of a Formulation Containing Cinnamaldehyde for Use in Treatment of oral fungal infections: An In Vivo Study. BioMed Res. Int., 2021. [DOI]
314. 314 Na, 2022, Weight of Evidence Approach for Skin Sensitization Potency Categorization of Fragrance Ingredients [DOI]
315. 315 Panico, 2019, Skin safety and health prevention: An overview of chemicals in cosmetic products
316. 316 Velambath, K.B., Mali, S.N., and Pratap, A.P. (2023). Greener Synthesis of Jasminaldehyde via Cross Aldol Condensation Reaction Using Recyclable Phase Transfer Catalysis and its Cosmetic Application. Lett. Appl. NanoBioSci., 12. [DOI]
317. 317 Meng, 2024, Study on the Effect of Different Aldehyde Modifiers on the Fume Suppression Effect, Mechanism and Road Performance of SBS Modified Asphalt [DOI]
318. 318 Pacholczyk-Sienicka, B., Ciepielowski, G., and Albrecht, Ł. (2021). The First Application of 1H NMR Spectroscopy for the Assessment of the Authenticity of Perfumes. Molecules, 26. [DOI]
319. 319 EFSA (2008). Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) on List of Alpha, Beta-unsaturated Aldehydes and Ketones Representative of FGE.19 Substances for Genotoxicity Testing. EFSA J., 910, 1–7.
320. 320 Lu, J., Zeng, X., Feng, Y., Li, S., Wang, Y., Liu, Y., Chen, F., Guan, Z., Chen, T., and Wei, F. (2023). Inhibitory Effects of Jasminum grandiflorum L. Essential Oil on Lipopolysaccharide-induced Microglia Activation-integrated Characteristic Analysis of Volatile Compounds, Network Pharmacology, and BV-2 Cell. Front. Pharmacol., 14. [DOI]
321. 321 Lee, 2022, Identification of Combinations of Endocrine Disrupting Chemicals in Household Chemical Products that Require Mixture Toxicity Testing [DOI]
322. 322 Matveychuk, 2016, Reactive Aldehydes and Neurodegenerative Disorders [DOI]
323. 323 Chen, 2022, Acrolein, an Endogenous Aldehyde Induces Alzheimer’s Disease-like Pathologies in Mice: A New Sporadic AD Animal Model [DOI]
324. 324 Sanotra, 2023, Acrolein Adducts and Responding Autoantibodies Correlate with Metabolic Disturbance in Alzheimer’s Disease [DOI]
325. 325 Sutaria, S.R., Gori, S.S., Morris, J.D., Xie, Z., Fu, X.-A., and Nantz, M.H. (2022). Lipid Peroxidation Produces a Diverse Mixture of Saturated and Unsaturated Aldehydes in Exhaled Breath That Can Serve as Biomarkers of Lung Cancer—A Review. Metabolites, 12. [DOI]
326. 326 Iacopetta, D., Ceramella, J., Baldino, N., Sinicropi, M.S., and Catalano, A. (2023). Targeting Breast Cancer: An Overlook on Current Strategies. Int. J. Mol. Sci., 24. [DOI]
327. 327 Vijayraghavan, 2023, Aldehyde-Associated Mutagenesis-Current State of Knowledge [DOI]
328. 328 Fang, 2024, The Cumulative and Single Effect of 12 Aldehydes Concentrations on Cardiovascular Diseases: An Analysis Based on Bayesian Kernel Machine Regression and Weighted Logistic Regression [DOI]
329. 329 Iacopetta, D., Ceramella, J., Catalano, A., Scali, E., Scumaci, D., Pellegrino, M., Aquaro, S., Saturnino, C., and Sinicropi, M.S. (2023). Impact of Cytochrome P450 Enzymes on the Phase I Metabolism of Drugs. Appl. Sci., 13. [DOI]
330. 330 Jackson, 2011, Update on the Aldehyde Dehydrogenase Gene (ALDH) Superfamily [DOI]
331. 331 Marchitti, 2008, Non-P450 Aldehyde Oxidizing Enzymes: The Aldehyde Dehydrogenase Superfamily [DOI]
332. 332 Zhang, 2023, The Role of Aldehyde Dehydrogenase 2 in Cardiovascular Disease [DOI]
333. 333 Somma, S., Reverchon, E., and Baldino, L. (2021). Water Purification of Classical and Emerging Organic Pollutants: An Extensive Review. ChemEngineering, 5. [DOI]
334. 334 Batsika, 2022, Light-promoted Oxidation of Aldehydes to Carboxylic Acids under Aerobic and Photocatalyst-free Conditions [DOI]
335. 335 Zhang, 2017, Catalyst-free Aerobic Oxidation of Aldehydes into Acids in Water under Mild Conditions [DOI]
336. 336 Peng, 2022, A Review of Plants Formaldehyde Metabolism: Implications for Hazardous Emissions and Phytoremediation [DOI]
337. 337 Ono, 2019, Improved Ultrasonic Degradation of Hydrophilic and Hydrophobic Aldehydes in Water by Combined Use of Atomization and UV Irradiation onto the Mist Surface [DOI]
338. 338 Talaiekhozani, 2016, Formaldehyde Removal from Wastewater and Air by Using UV, Ferrate(VI) and Uv/Ferrate(VI) [DOI]
339. 339 Wang, 2020, Experimental and Theoretical Studies on the Removal Mechanism of Formaldehyde from Water by Mesoporous Calcium Silicate [DOI]
340. 340 Salehi, 2020, Adsorptive Removal of Acetaldehyde from Water Using Strong Anionic Resins Pretreated with Bisulfite: An Efficient Method for Spent Process Water Recycling in Petrochemical Industry [DOI]
341. 341 Zhu, P., Chen, X., and Roberts, C.G. (2024, October 18). Method of Use for Aldehyde Removal (US7041220 B2). Available online: https://patents.google.com/patent/US7041220B2/en.
342. 342 Adeniyi, 2023, The Theoretical Study of the Oxidation Reaction of Hydroxyl Radical for the Removal of Volatile Organic Aliphatic and Aromatic Aldehydes from the Atmosphere [DOI]
343. 343 Kim, 2018, Phytoremediation of Volatile Organic Compounds by Indoor Plants: A Review [DOI]
344. 344 Faungnawakij, 2004, Removal of Acetaldehyde in Air Using a Wetted—Wall Corona Discharge Reactor [DOI]
345. 345 Sung, 2010, Evaluation of an Air-cleaning Unit Having Photocatalytic Sheets to Remove Acetaldehyde from Indoor Air [DOI]
346. 346 Peng, 2018, Aminated Mesoporous Silica Nanoparticles for the Removal of Low-concentration Malodorous Aldehyde Gases [DOI]
347. 347 Wu, 2021, Reduction of Aldehyde Emission and Attribution of Environment Burden in Cooking Fumes from Food Stalls Using a Novel Fume Collector [DOI]
348. 348 Vikrant, 2020, Utilization of Metal–organic Frameworks for the Adsorptive Removal of an Aliphatic Aldehyde Mixture in the Gas Phase [DOI]
349. 349 Jamshidi, 2018, Biofiltration of Formaldehyde, Acetaldehyde, and Acrolein from Polluted Airstreams Using a Biofilter [DOI]

Cited by 85

Showing 44 of 85 known citations — external sources report more than can currently be individually listed.

Related research

• Introduction to a New MDPI Open Access Journal: Organics — shares topic coverage
• On the Question of Zwitterionic Intermediates in the [3+2] Cycloaddition Reactions: A Critical Review — shares topic coverage
• A Review of the Synthetic Strategies toward Dihydropyrrolo[1,2-a]Pyrazinones — shares topic coverage
• Acknowledgment to the Reviewers of Organics in 2022 — shares topic coverage
• Parallel Synthesis of Aurones Using a Homogeneous Scavenger — shares topic coverage