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Research Article Open access CC BY 4.0

One Pot Synthesis and Spectroscopic Characterization of Novel 8-Azacoumarin Derivatives as Eco-Friendly Insecticidal Agents

Mohamed, A. A. Shaymma, Sameh A. Rizk, Khalil Ali

International Research Journal of Pure and Applied Chemistry · pp. 1–11 · Published 31 Oct 2018

10.9734/IRJPAC/2018/44129

Abstract

A series of five 8-azacoumarin derivatives bearing aryl moieties at C-5 and C-7 designed and synthesised by a concise procedure utilising grinding and ultrasound approaches. The multi-component protocols proceeded smoothly in the absence of solvent to furnish the target products in moderate to good yields. All the synthesised molecules characterised via 1HNMR, 13CNMR, IR, Mass spectra, and elemental analyses.  In this article, we examined the insecticidal activity of some of the synthesized 8-azacoumarin derivatives as a new trend to the control cotton leafworm Spodoptera littoralis that considered the most serious attacking pest on cotton.

Azacoumarin chalcones ultrasonic irradiation grindstone insecticidal activity and cotton leafworm Spodoptera littoralis.

Cited by 2

Recent advances in the pesticide activities of chalcone derivatives

Pengxiang Guo, Hongliang Xu, Wanjie Zhang · Pest Management Science · 2025

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