A Facile Synthesis of 7-amino-1,3-diaryl-5-phenyl-2-thioxo-pyrano[2,3-d]pyrimidine-4(5H)-ones
Nimalini Moirangthem, Warjeet S. Laitonjam
Chemical Science International Journal · pp. 58–70 · Published 4 Jul 2011
10.9734/ACSJ/2011/345Abstract
The reactions of arylidene derivatives such as ethylphenylmethylenemalononitrile 3a, ethylphenylmethylenecyanoacetate 3b and ethylphenylmethylenecyano-acetamide 3c with substituted thiobarbituric acids 2a-e in presence of NaOCH3 and MeOH afforded 7-amino-1,3-diaryl-5-phenyl-2-thioxo-pyrano[2,3-d]pyrimidin-4(5H)ones 4a-e and 5e by cyclocondensation.
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