Albashir Tahir, Nura Bello, Khadija Aminu Mato, Rayyan Muhammad Bawa, Shamsiyya Bala Aliyu, Ahmed Faizu Saleh & Eudora Obioma Nwanaforo·International Research Journal of Oncology·2026
Background: The tumour immune microenvironment (TIME) is a dynamic immunosuppressive network of cellular and molecular mediators that promotes immune evasion and limits the efficacy of current immunotherapeutic strategies. Aim: This review critically evaluates plant-derived phyto...
Open access
Research Article10.9734/irjo/2026/v9i2240
Uduebor Osazee, D. Chiegboka, Chrysanthus, Akhaine J. Precious, Edigberhi Emmanuel, Precious O. Ilenloh, Emmanuel Okun U., Omenazu V. Chidiebere, Elvis U. Edokpolor & Samuel Oyakhire·International Research Journal of Oncology·2026
Background: Breast cancer in men is rare, accounting for approximately 1% of breast cancer cases. Hormone-receptor-positive disease accounts for the majority of male breast cancers, whereas triple-negative disease is extremely uncommon. Evidence specific to men remains limited be...
Open access
Research Article10.9734/irjo/2026/v9i2239
Infectious agents remain among the few modifiable causes of human cancer for which prevention has already altered population-level incidence, yet the intellectual boundaries of the field have shifted substantially. Classical infectious carcinogenesis, built on a small set of viru...
Open access
Research Article10.9734/irjo/2026/v9i2238
Background: Uterine smooth-muscle tumours of uncertain malignant potential (STUMP) present diagnostic and surveillance challenges, particularly when extensive pelvic involvement coexists with urinary tract obstruction. This report describes a patient with a large pelvic smooth-mu...
Open access
Research Article10.9734/irjo/2026/v9i2237
Background: Human papillomavirus (HPV) is a common sexually transmitted infection and a cause of cervical cancer. Vaccination is effective, yet coverage remains low in many low- and middle-income countries. Nigeria struggles with scale-up, particularly in Rivers State. Aim: This...
Open access
Research Article10.9734/irjo/2026/v9i2236
Nesrine Mejri, Myriam Saadi, Lilia Ghorbal, Senyefia Bosson-Amedenu, Theodore Oduro-Okyireh, Anthony Joe Turkson & Noureddine Ouerfelli·International Research Journal of Oncology·2026
Background: Cancer incidence and mortality impose a substantial health burden in Tunisia. Understanding the relationships among key epidemiological indicators is essential for assessing cancer patterns and their public health implications. Aim: This study examined patterns in nat...
Open access
Research Article10.9734/irjo/2026/v9i2235
The integration of patient-derived cancer organoids with artificial intelligence (AI) offers a potential approach for developing more individualised models of tumour behaviour and therapeutic response. Conventional precision oncology relies heavily on static molecular measurement...
Open access
Research Article10.9734/irjo/2026/v9i2234
Prostate cancer is a major and increasing cause of cancer morbidity and mortality among African men, yet the value of early detection depends on more than whether a prostate-specific antigen test is available. Screening decisions are shaped by knowledge, perceived susceptibility,...
Open access
Research Article10.9734/irjo/2026/v9i2233
Adesina Saheed Musa, Felix Olayemi Fagbomedo, Adeniyi Taofeeq Abiodun, Marcia Fernando Mariano & Isabel’s Bartolomeu Pascoal·International Research Journal of Oncology·2026
Androgen deprivation remains the therapeutic foundation of advanced prostate cancer, yet the durability of response is limited and progression to castration-resistant disease is close to universal. Genomic explanations centred on androgen receptor amplification, point mutation an...
Open access
Research Article10.9734/irjo/2026/v9i2232
Background: Male Breast Cancer (MBC) is a rare but serious malignancy often diagnosed at advanced stages due to a profound lack of awareness. In Nigeria, MBC remains understudied, particularly among young male populations in tertiary institutions. Objective: This study assessed t...
Open access
Research Article10.9734/irjo/2026/v9i2231
Background: Human papillomavirus (HPV) vaccination remains one of the most effective strategies for preventing cervical cancer. However, vaccine uptake among women in many low- and middle-income countries remains suboptimal due to social, economic, and health system challenges. A...
Open access
Research Article10.9734/irjo/2026/v9i2230
Houmada Amina, El Hassouni Mohammed Reda, LAHNAOUI Oumayma, El Bouazizi Yassine, EL MOUATASSIM Zakaria, MAJBAR Mohammed Anass & SOUADKA Amine·International Research Journal of Oncology·2026
Background: Desmoplastic small round cell tumour (DSRCT) is a rare, aggressive mesenchymal neoplasm that typically disseminates along the peritoneal and serosal surfaces of the abdominopelvic cavity in adolescent and young adult males. Isolated presentations confined to a non-ser...
Open access
Research Article10.9734/irjo/2026/v9i2229
Chronic myeloid leukaemia (CML) has been transformed by BCR::ABL1 tyrosine kinase inhibitors (TKIs), and for many patients life expectancy now approaches that of the general population. Against this background, treatment-free remission (TFR), defined as the maintenance of molecul...
Open access
Research Article10.9734/irjo/2026/v9i2228
Aims: To report an unusual case of conjunctival CD20-positive B-cell lymphoma with high-grade cytological features in a young adult that initially mimicked a benign conjunctival lesion, and to emphasise the diagnostic limitations of a restricted immunohistochemical panel. Present...
Open access
Research Article10.9734/irjo/2026/v9i2227
Background: Industrial workers may encounter occupational and lifestyle-related risk factors for lung cancer, while their knowledge of preventive measures may be limited. Aims: This study evaluated the effectiveness of a structured teaching programme on knowledge regarding lung c...
Open access
Research Article10.9734/irjo/2026/v9i2226