Background: Previous prostate cancer research has often been conducted in clinical or laboratory settings and has relied on traditional survival models that focus on a single disease endpoint. Such approaches do not fully account for intermediate disease states, transition risks,...
Open access
Research Article10.9734/irjo/2026/v9i2218
Joy Taiye Babalola, Okeoghene Marcel Edafetanure-Ibeh, Quadri O. Adewuyi, Favour Chibuzor, Sonay Unsal, Monsuru Olarewaju Moshood, Michael Kyere & Oluwadunsin Rachael Ajayi·International Research Journal of Oncology·2026
Cancer remains a major global health challenge, creating a continuing need for safer, effective and sustainable therapeutic discovery. Plant-derived phytochemicals have contributed substantially to oncology drug development, and many clinically used anticancer agents originate di...
Open access
Research Article10.9734/irjo/2026/v9i2217
Background: Urban-rural differences in ovarian cancer remain insufficiently described in Central Asia, and evidence from Uzbekistan is limited. This study assessed national trends and interregional differences in registered ovarian cancer incidence by type of residence in Uzbekis...
Open access
Research Article10.9734/irjo/2026/v9i2216
Background: The Gleason grading system is the gold standard for assessing prostate cancer aggressiveness. Whether serum Prostate Specific Antigen (PSA) and testosterone can predict histological grade remains debated, with limited data from West African populations. Aim: The study...
Open access
Research Article10.9734/irjo/2026/v9i2215
Mehdi Alem, Sara Nejjari, Assiya Benamar, Mounir Belcadi Abbassi, Maryam Msakem, Diango Keita, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim, Samia Arifi, Touria Bouhafa & Nawfel Mellas·International Research Journal of Oncology·2026
Background: Malignant glomus tumors are rare neoplasms, and vulvar involvement is exceptionally uncommon, creating significant diagnostic challenges. Aims: This case study reports an exceptional case of malignant glomus tumor of the vulva presenting with small round cell morpholo...
Open access
Research Article10.9734/irjo/2026/v9i2214
Mehdi Alem, Sara Nejjari, Assiya Benamar, Mounir Belcadi Abbassi, Maryam Msakem, Diango Keita, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim, Samia Arifi, Touria Bouhafa & Nawfel Mellas·International Research Journal of Oncology·2026
Background: Ewing's sarcoma (ES) arising from the pleura is an exceedingly rare entity, accounting for fewer than 2% of all ES cases. Its rarity and non-specific clinical presentation frequently result in diagnostic delays and therapeutic challenges. Presentation of Cases: We rep...
Open access
Research Article10.9734/irjo/2026/v9i2211
Oral cancer remains a critical global health challenge, with rising trends, particularly in South and Southeast Asia. In Myanmar, the disease represents a significant public health crisis, consistently ranking among the top ten causes of morbidity and mortality. Epidemiological d...
Open access
Research Article10.9734/irjo/2026/v9i2212
Isabela Sacco Camara, Aline Pelosini Gomes, Olívia Voelzke Passarin, Amanda Scaff Mendes, Kalil Sallum Haddad Dib & Juliano dos Santos·International Research Journal of Oncology·2026
Background: Glioblastoma is an aggressive primary brain tumour with poor survival outcomes, where distinguishing true tumour recurrence from treatment-related pseudoprogression on post-therapy MRI remains a major clinical challenge. Aims: The primary objective of this study was t...
Open access
Research Article10.9734/irjo/2026/v9i2213
Cervical cancer remains one of the most preventable yet still highly lethal malignancies among women in low- and middle-income countries, particularly in sub-Saharan Africa. In Cameroon, despite the availability of effective preventive tools such as human papillomavirus vaccinati...
Open access
Research Article10.9734/irjo/2026/v9i2210
Background: Oligometastatic disease represents an intermediate biological state between localized cancer and widely disseminated metastases. Increasing evidence suggests that aggressive local treatment directed at limited metastatic deposits may improve disease control in selecte...
Open access
Research Article10.9734/irjo/2026/v9i2209
Lydia Amarachi Onwuemelem, Oluwatomilayo Oluwayinka Fasesin, Oluwafunmilayo E. O. Adetona, Ndidi Atasie Eboh, Leo Tata & Uchechukwu Lilian Okoye·International Research Journal of Oncology·2026
Benign gynaecological tumours, such as uterine fibroids (leiomyomas) and ovarian teratomas, are non-malignant proliferative growths that occur in the reproductive system of young females but differ substantially in their origin, clinical behaviour, and management. The aim of this...
Open access
Research Article10.9734/irjo/2026/v9i1208
Obiageri Ihuarulam Okeoma, Godwin Kenechukwu Nwajiugo, Uchechukwu Mercy Ejike, Oluwafunmilayo E. O. Adetona, Uchechukwu Lilian Okoye, Yolanda Molkuh Emmanuel & Lydia Amarachi Onwuemelem·International Research Journal of Oncology·2026
Background: Benign reproductive tumours, such as uterine fibroids, ovarian cysts and endometrial polyps, are extremely common in women of childbearing age and contribute to gynaecological morbidity to a significant degree. Among these, uterine fibroids demonstrate a cumulative li...
Open access
Research Article10.9734/irjo/2026/v9i1207
Metastatic endometrial carcinoma is typically approached with palliative intent, with durable remission considered uncommon. We report the case of a 63-year-old woman presenting with Stage IVB endometrial carcinoma with hepatic and skeletal metastases. Histopathology revealed hig...
Open access
Research Article10.9734/irjo/2026/v9i1206
Background: Modern targeted and immune cancer therapies have shifted cardiotoxicity from acute myocardial damage to a chronic, multifaceted cardiovascular risk involving vascular, metabolic, and immune-mediated mechanisms. Aim: To delineate the emerging triad of chronic cardiovas...
Open access
Research Article10.9734/irjo/2026/v9i1205
Lydia Amarachi Onwuemelem, Olufemi Adesola Adedayo, N. Ohale Sandra, Gbadebo Moses Adetoyi, Morolake Martina Olabanji & Ndidi Atasie Eboh·International Research Journal of Oncology·2026
Cancer remains a major global health challenge, with a disproportionate burden in low and middle-income countries (LMICs), with lack of diagnostic services results in late diagnosis and poor outcomes. While histopathology is the standard for cancer diagnosis, its impact in low-re...
Open access
Research Article10.9734/irjo/2026/v9i1204