Cervical cancer remains one of the most preventable yet still highly lethal malignancies among women in low- and middle-income countries, particularly in sub-Saharan Africa. In Cameroon, despite the availability of effective preventive tools such as human papillomavirus vaccinati...
Open access
Research Article10.9734/irjo/2026/v9i2210
Background: Oligometastatic disease represents an intermediate biological state between localized cancer and widely disseminated metastases. Increasing evidence suggests that aggressive local treatment directed at limited metastatic deposits may improve disease control in selecte...
Open access
Research Article10.9734/irjo/2026/v9i2209
Lydia Amarachi Onwuemelem, Oluwatomilayo Oluwayinka Fasesin, Oluwafunmilayo E. O. Adetona, Ndidi Atasie Eboh, Leo Tata & Uchechukwu Lilian Okoye·International Research Journal of Oncology·2026
Benign gynaecological tumours, such as uterine fibroids (leiomyomas) and ovarian teratomas, are non-malignant proliferative growths that occur in the reproductive system of young females but differ substantially in their origin, clinical behaviour, and management. The aim of this...
Open access
Research Article10.9734/irjo/2026/v9i1208
Obiageri Ihuarulam Okeoma, Godwin Kenechukwu Nwajiugo, Uchechukwu Mercy Ejike, Oluwafunmilayo E. O. Adetona, Uchechukwu Lilian Okoye, Yolanda Molkuh Emmanuel & Lydia Amarachi Onwuemelem·International Research Journal of Oncology·2026
Background: Benign reproductive tumours, such as uterine fibroids, ovarian cysts and endometrial polyps, are extremely common in women of childbearing age and contribute to gynaecological morbidity to a significant degree. Among these, uterine fibroids demonstrate a cumulative li...
Open access
Research Article10.9734/irjo/2026/v9i1207
Metastatic endometrial carcinoma is typically approached with palliative intent, with durable remission considered uncommon. We report the case of a 63-year-old woman presenting with Stage IVB endometrial carcinoma with hepatic and skeletal metastases. Histopathology revealed hig...
Open access
Research Article10.9734/irjo/2026/v9i1206
Background: Modern targeted and immune cancer therapies have shifted cardiotoxicity from acute myocardial damage to a chronic, multifaceted cardiovascular risk involving vascular, metabolic, and immune-mediated mechanisms. Aim: To delineate the emerging triad of chronic cardiovas...
Open access
Research Article10.9734/irjo/2026/v9i1205
Lydia Amarachi Onwuemelem, Olufemi Adesola Adedayo, N. Ohale Sandra, Gbadebo Moses Adetoyi, Morolake Martina Olabanji & Ndidi Atasie Eboh·International Research Journal of Oncology·2026
Cancer remains a major global health challenge, with a disproportionate burden in low and middle-income countries (LMICs), with lack of diagnostic services results in late diagnosis and poor outcomes. While histopathology is the standard for cancer diagnosis, its impact in low-re...
Open access
Research Article10.9734/irjo/2026/v9i1204
Samuel Bamidele Afolabi, TOBECHI BRENDAN NNANNA, Glory Ojoma, Simon, Damian Ndubuisi NWAJEI, Victor Damilare Oladele, Adibia, Umoroye Nathan & Tobiloba Philip Olatokun·International Research Journal of Oncology·2026
Hematological malignancies, including leukemias, lymphomas, myelomas, and myelodysplastic syndromes, impose a substantial global health burden, accounting for approximately 10% of all new cancer diagnoses worldwide. Early identification of pre-malignant blood cells a critical win...
Open access
Research Article10.9734/irjo/2026/v9i1203
Kaladada Ibitrokoemi Korubo, Akpevwe Deborah Maduka, Emmanuel Wobo, Paxman Dandyson Uku, Uchechukwu Prince Okite & Chijioke Adonye Nwauche·International Research Journal of Oncology·2026
Background: Chronic lymphocytic leukaemia (CLL) outcomes in low-resource settings are shaped not only by disease biology, but also by delayed diagnosis, limited access to therapeutic options, and treatment interruptions due to social and financial reasons. However, data describin...
Open access
Research Article10.9734/irjo/2026/v9i1202
Cervical cancer is the leading cause of cancer death and the third most common cancer in women worldwide, the second most common cancer in India. Around 90% of cases of cervical cancer are found in low- and middle-income nations, and deaths from cervical cancer in high-income nat...
Open access
Research Article10.9734/irjo/2026/v9i1201
Background: In resource-limited settings, the diagnosis of multiple myeloma (MM) often relies on serum protein electrophoresis (SPE), which lacks sensitivity for light chain-only and oligo-secretory disease. This study evaluates the diagnostic utility of serum free light chain (s...
Open access
Research Article10.9734/irjo/2026/v9i1200
Background: Palliative care (PC) enhances quality of life for patients with life-limiting illnesses. Yet, its integration into haematology remains suboptimal in many settings. In Ghana, although palliative care services are gradually expanding, evidence on how haematologists perc...
Open access
Research Article10.9734/irjo/2026/v9i1199
Esther Uyoyooghene Olokede, Kingsley Ugonna Ugoagwu, Olusegun Timothy God-Giveth, Motunrayo Victoria Adigun, Fortune Itoje Ebiala & Salifu Faisal·International Research Journal of Oncology·2026
Spatial transcriptomics and related spatially resolved profiling technologies have transformed the characterization of tumor microenvironment architecture, revealing spatial patterns of cellular organization that are tightly linked to cancer behavior. However, despite their biolo...
Open access
Research Article10.9734/irjo/2026/v9i1198
Introduction: Breast cancer management is increasingly shifting toward minimally invasive procedures. While neoadjuvant chemotherapy (NACT) is used to downstage locally advanced disease, it can induce lymphatic fibrosis, potentially compromising the identification rate (IR) and f...
Open access
Research Article10.9734/irjo/2026/v9i1197
Background: Breast cancer remains a major public health challenge in low- and middle-income countries, disproportionately affecting women. It is a multifactorial disease arising from complex interactions between genetic, molecular, hormonal, environmental, and lifestyle factors....
Open access
Research Article10.9734/irjo/2026/v9i1194