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All published articles 232

A Narrative Review on Machine Learning Methods for Pre-Malignant Blood Cells Identification in Hematological Malignancies

Samuel Bamidele Afolabi, TOBECHI BRENDAN NNANNA, Glory Ojoma, Simon, Damian Ndubuisi NWAJEI, Victor Damilare Oladele, Adibia, Umoroye Nathan & Tobiloba Philip Olatokun · International Research Journal of Oncology · 2026

Hematological malignancies, including leukemias, lymphomas, myelomas, and myelodysplastic syndromes, impose a substantial global health burden, accounting for approximately 10% of all new cancer diagnoses worldwide. Early identification of pre-malignant blood cells a critical win...

Open access Research Article 10.9734/irjo/2026/v9i1203

Real-World Care Gaps and Survival Outcomes in Chronic Lymphocytic Leukaemia: A 20-Year Retrospective Study from Nigeria

Kaladada Ibitrokoemi Korubo, Akpevwe Deborah Maduka, Emmanuel Wobo, Paxman Dandyson Uku, Uchechukwu Prince Okite & Chijioke Adonye Nwauche · International Research Journal of Oncology · 2026

Background: Chronic lymphocytic leukaemia (CLL) outcomes in low-resource settings are shaped not only by disease biology, but also by delayed diagnosis, limited access to therapeutic options, and treatment interruptions due to social and financial reasons. However, data describin...

Open access Research Article 10.9734/irjo/2026/v9i1202

Prevalence of Cervical Cancer among Women Aged 20–60 Years in Assam using Liquid-based Cytology

Suman Kumari, Ripunjoy Deka, Wasim Akram Hussain & Biswajit Roy · International Research Journal of Oncology · 2026

Cervical cancer is the leading cause of cancer death and the third most common cancer in women worldwide, the second most common cancer in India. Around 90% of cases of cervical cancer are found in low- and middle-income nations, and deaths from cervical cancer in high-income nat...

Open access Research Article 10.9734/irjo/2026/v9i1201

Clinical Utility of Serum Free Light Chain Assays in Multiple Myeloma: A 10-Year Multicentre Comparison with Serum Protein Electrophoresis in South-South Nigeria

Kaladada Ibitrokoemi Korubo, Paxman Dandyson Uku, Emmanuel Wobo, Akpevwe Deborah Maduka & Chijioke Adonye Nwauche · International Research Journal of Oncology · 2026

Background: In resource-limited settings, the diagnosis of multiple myeloma (MM) often relies on serum protein electrophoresis (SPE), which lacks sensitivity for light chain-only and oligo-secretory disease. This study evaluates the diagnostic utility of serum free light chain (s...

Open access Research Article 10.9734/irjo/2026/v9i1200

Clinician Perceptions of Palliative Care and its Role in Haematological Practice: An Exploratory Study in Ghana

Gifty Zainabu Asim, Irene Korkoi Aboh & Rasheed Ofosu-Poku · International Research Journal of Oncology · 2026

Background: Palliative care (PC) enhances quality of life for patients with life-limiting illnesses. Yet, its integration into haematology remains suboptimal in many settings. In Ghana, although palliative care services are gradually expanding, evidence on how haematologists perc...

Open access Research Article 10.9734/irjo/2026/v9i1199

From Spatial Transcriptomics to Clinic-Ready Diagnostic Panels: A Conceptual Review of Translating Tumor Microenvironment Architecture into Practical Cancer Biomarkers

Esther Uyoyooghene Olokede, Kingsley Ugonna Ugoagwu, Olusegun Timothy God-Giveth, Motunrayo Victoria Adigun, Fortune Itoje Ebiala & Salifu Faisal · International Research Journal of Oncology · 2026

Spatial transcriptomics and related spatially resolved profiling technologies have transformed the characterization of tumor microenvironment architecture, revealing spatial patterns of cellular organization that are tightly linked to cancer behavior. However, despite their biolo...

Open access Research Article 10.9734/irjo/2026/v9i1198

De-escalating the Axilla: A Systematic Evaluation of Sentinel Lymph Node Biopsy Reliability and Oncological Safety in the Post-Neoadjuvant Landscape

Swarnava Chanda, Abdul Quadir Rahmani & Dhairya Gupta · International Research Journal of Oncology · 2026

Introduction: Breast cancer management is increasingly shifting toward minimally invasive procedures. While neoadjuvant chemotherapy (NACT) is used to downstage locally advanced disease, it can induce lymphatic fibrosis, potentially compromising the identification rate (IR) and f...

Open access Research Article 10.9734/irjo/2026/v9i1197

Prevalence and Patterns of Breast Lesions among Women Presenting with Palpable Breast Lumps at Kiambu Level 5 Hospital in Kiambu County, Kenya

Gichana Cornelius Musemi, Mutuku Onesmus Muia, Njenga John & Maundu Molly · International Research Journal of Oncology · 2026

Background: Breast cancer remains a major public health challenge in low- and middle-income countries, disproportionately affecting women. It is a multifactorial disease arising from complex interactions between genetic, molecular, hormonal, environmental, and lifestyle factors....

Open access Research Article 10.9734/irjo/2026/v9i1194

The Role of MicroRNA in Prostate Cancer: A Review Based on Nigerian Population

Saheed A. Adekola, Mathew F. Olaniyan, Bukhari Isah Shuaibu, Muhibi Musa Abidemi, Idris N. Abdullahi, Mustapha. U. Bakare, Khadijat. T. Musah, Sodiq A. Adekola & Dhikroh. O. Adekola · International Research Journal of Oncology · 2026

Background: Prostate cancer is a major killer among men worldwide, hitting Nigeria especially hard with late diagnoses and fast-spreading tumours. MicroRNAs such as miR-21, miR-141, miR-375, and miR-221/222 play central roles in driving cancer growth and spread by fine-tuning gen...

Open access Research Article 10.9734/irjo/2026/v9i1195

The Relationship between Breast Cancer Literacy and (e) Health Literacy among Urban Women in Ariyalur, Tamil Nadu

J. Shabana Yasmin · International Research Journal of Oncology · 2026

Aim: To assess the relationship between Breast Cancer Literacy and (e)Health Literacy among urban women in Ariyalur town, Tamil Nadu. Study Design: Community-based cross-sectional study. Place and Duration of Study: Ariyalur town, Tamil Nadu, India, during May 2023. Methodology:...

Open access Research Article 10.9734/irjo/2026/v9i1196

Targeted and Immunotherapeutic Approaches in Cancer: A Narrative Review of Evolving Evidence and Clinical Implications

J. Sunitha Blessy, Flowrence Evangelin Kona, Rokkam Vanya Sri, Harathi Kovvuri, M. John Winkle, Soujanya Ferdinand, B. Bhavani & K. Padmalatha · International Research Journal of Oncology · 2026

Cancer treatment has undergone a profound transformation over the past two decades, evolving from non-specific cytotoxic chemotherapy toward precision-based targeted therapies and immunotherapeutic strategies. Advances in molecular oncology have enabled the identification of onco...

Open access Research Article 10.9734/irjo/2026/v9i1193

Ovarian Cancer Research: A Strategic Survey Analysis for Breakthroughs in Early Detection and Therapy

Chauhan Manshi, Ghildiyal Pallavi, Negi Ruchita, Bisht Nidhi, Abhijeet Singh & Gupta Piyush · International Research Journal of Oncology · 2025

Introduction: Ovarian cancer is one of the most lethal gynecological malignancies and is often referred to as the “silent killer” due to the absence of specific symptoms in its early stages. Late detection contributes to high mortality rates globally. This study aimed to assess w...

Open access Research Article 10.9734/irjo/2025/v8i2192

Epidemiological Profile and Associated Risk Factors in Head and Neck Cancer in A North Indian Population: A Cross-Sectional Observational Study

Ashwani Yadav, Suman Kharkwal, Pranav Singhal & Archana Yadav · International Research Journal of Oncology · 2025

Background: Head and Neck Squamous Cell Carcinoma (HNSCC) accounts for a substantial proportion of cancer cases globally and represents a significant contributor to cancer-related morbidity and mortality, particularly in India. The global incidence of HNSCC is steadily increasing...

Open access Research Article 10.9734/irjo/2025/v8i2191

Precision Frontiers in Mantle Cell Lymphoma: Tailored Therapies and Emerging Innovations

Apeksha Dasharath Rajguru, Anuprita Tejesh Kamble, Akshada Devendra Khetre & Falgunee Dasharath Ghadi · International Research Journal of Oncology · 2025

Introduction: Mantle cell lymphoma (MCL) is a rare and aggressive form of B-cell non-Hodgkin lymphoma, representing 5%-7% of cases, with a median age at diagnosis around 65 years. Historically, MCL was considered incurable, with chemotherapy offering only temporary remission. Rec...

Open access Research Article 10.9734/irjo/2025/v8i2190

A Giant Ovarian Sex Cord Stromal Tumor Presenting as a Massive Abdomino-pelvic Mass: A Rare Case Report

Swarnava Chanda · International Research Journal of Oncology · 2025

Objective: To present a case report of ovarian spindle cell neoplastic lesions with sex cord stromal differentiation, highlighting diagnostic challenges in the absence of immunohistochemistry (IHC). Methods: Clinical, radiological, surgical, and histopathological data were review...

Open access Research Article 10.9734/irjo/2025/v8i2189