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All published articles 232

Next-Gen Gene Editing and Programmable Chromosome Engineering for Potential Cancer Gene Mutation Therapeutics

Salvation Ifechukwude Atalor, Jumoke Ologun, Modinat Aina, Abayomi, Obiageri Ihuarulam Okeoma, Opeoluwa Alayande, Awah Favour Matthew, Reginald Oyortey & Lawrence John AJutor · International Research Journal of Oncology · 2025

Gene editing technologies have revolutionized the approach to treating cancer by enabling precise modifications to the genome, particularly through programmable chromosome engineering techniques that allow for large-scale rearrangements, deletions, and insertions to correct or di...

Open access Research Article 10.9734/irjo/2025/v8i2187

Comparison of Surgical and Medical Management of Symptomatic Fibrocystic Breast Changes: A Prospective Pilot Study

Shrikanta Biswas & Pallabi Hazra · International Research Journal of Oncology · 2025

Background: Fibrocystic breast changes (FBC), a common benign condition affecting up to 50% of reproductive-age women, often present with mastalgia and nodularity. While medical management is first-line, surgical excision is considered for refractory cases. Aim: This single-centr...

Open access Research Article 10.9734/irjo/2025/v8i2188

Awareness, Knowledge and Utilisation of Breast Cancer Screening among Women of Reproductive Age in Keffi, Nigeria

Owoyele Mercy Ehi, Bassi Amos, Ibrahim Ismaila, David Emmanuel, Tunde-Olatunji Olubunmi Abidemi & Ekueme, C. Vitus · International Research Journal of Oncology · 2025

Background: In 2022 alone, the World Health Organisation estimated that breast cancer caused 670000 deaths globally. Breast cancer is a significant public health concern worldwide. It is a disease in which abnormal breast cells grow out of control and form tumours. It is the main...

Open access Research Article 10.9734/irjo/2025/v8i2186

Leveraging Artificial Intelligence in Studying Inflammation-driven Leukemogenesis: A New Frontier in Predicting Malignant Tumour Shifts

Oluwatobiloba Kehinde Adedokun, Temitope Emmanuel Alo, Kazeem Olanrewaju Bankole, Modinat Aina, Abayomi, Nanmet Ephraim Panwal, Jeremiah Tella & Lawrence John AJutor · International Research Journal of Oncology · 2025

While genetic mutations are well-known triggers for leukaemia, inflammation plays a big part by messing with cell growth and immune responses, yet its complex patterns are hard to track with traditional methods. This review looks at how artificial intelligence (AI) and machine le...

Open access Research Article 10.9734/irjo/2025/v8i2185

Lymphedema of Tongue: Evaluation, Management and Outcomes

Jagmohan Lal Meena, Blossom Baby, S.K Meena & Simanta Buragohain · International Research Journal of Oncology · 2025

Lymphedema is a chronic, progressive condition of the lymphatic system characterized by inflammation, fibro adipose tissue deposition, and impaired lymphatic drainage. Lingual lymphedema, in particular, poses unique challenges due to the critical role of the tongue in oral motor...

Open access Research Article 10.9734/irjo/2025/v8i2184

Detection of BK Virus Cytopathic Effect in Urine Samples of Sudanese Patients with Prostatic Cancer

Rifga Mohammed Suliman Ali, Asma Al-Ameer M. Zeen, Hadia Abass Eltaib Ahmed, Mohammed Abdelgader Elsheikh & Ghanem Mohammed Mahjaf · International Research Journal of Oncology · 2025

Background: Prostate cancer is one of the most common cancers among men. Some studies suggest a potential link between BK virus infection and the development of this cancer, highlighting the need for further investigation. Objectives: This study aims to detect BK virus in the uri...

Open access Research Article 10.9734/irjo/2025/v8i2182

Solid Pseudopapillary Neoplasm of the Pancreas with Multiple Liver Metastases: A Rare Case Report with Literature Review

BOUFELOUSSEN Mohammed, MERGHAD Hatim, ABOUKER Ibrahim, EL MESSAOUDI Imane, EL MOUATASSIM Zakaria, LAHNAOUI Oumayma, MAJBAR Mohammed Anass, SOUADKA Amine & BENKABBOU Amine · International Research Journal of Oncology · 2025

Solid and pseudopapillary tumor (SPT) of the pancreas is a rare relatively low grade malignant neoplasm metastasizing in only 5–15% of cases, the most common location is in the liver. This tumor affects young women in the majority of the cases. We report a case of SPT in a 67 yea...

Open access Research Article 10.9734/irjo/2025/v8i2183

Evaluating the Acute Toxicities by Using Bolus throughout vs. Alternate Days in Locally Advanced Post-Mastectomy Breast Cancer Patients Receiving Hypo-fractionated Radiotherapy

Kamrun Nahar Liza, Muhammad Masudul Hassan Arup, Tasneem Hossain, Marzia Afrin Reme, Farjana Rashid & Tarim Mahmood · International Research Journal of Oncology · 2025

Background: Hypo-fractionated radiotherapy has gained popularity in the management of post-mastectomy breast cancer owing to its reduced treatment duration while maintaining efficacy. However, this approach, particularly when combined with bolus material, raises concerns regardin...

Open access Research Article 10.9734/irjo/2025/v8i2181

Diagnosis and Treatment of a Vaterian Ampulloma: A Rare Case Report

MERGHAD Hatim, ABOUKER Ibrahim, BOUFELOUSSEN Mohammed, ASATASH Yousra, ZAHRAOUI Anass, EL MOUATASSIM Zakaria, LAHNAOUI Oumaima, SOUADKA Amine, MAJBAR Mohammed Anass & BENKABBOU Amine · International Research Journal of Oncology · 2025

Ampullary neuroendocrine neoplasms (Amp-NENs) are relatively uncommon histological tumors within the Vaterian ampulla of the duodenum. Duodenal neuroendocrine neoplasms (NENs) are a rare entity, but the incidence has been increasing during the last few years. Amp-NENs exhibit dis...

Open access Research Article 10.9734/irjo/2025/v8i1180

Survival in Soft Tissue Sarcomas in Hispanics vs Non-hispanic Whites: A Single-centre Experience

Diana Zamora, Silpa Choday, Anthony Yeung & Miguel Gonzalez · International Research Journal of Oncology · 2025

Background: Racial, ethnic, and socioeconomic factors have been implicated in the variability of survival rates among soft tissue sarcoma (STS). These disparities are multifactorial and may reflect differences in disease biology, access to care, treatment responses, and others. I...

Open access Research Article 10.9734/irjo/2025/v8i1179

Relationship between Age and Cancer among Women at the National Cancer Control Foundation in Ibb City, Yemen, 2024

Noman Ahmed Yahya Al Hatemi, Haddad Salim Alhebshi, Wajeeh Al-Wassiah, Wadhah Abdo Ahmed, Maram AI-Qaderi, Hebah Nasser & Mohammed Sadeq Al-Thawabi · International Research Journal of Oncology · 2025

Introduction: Cancer is one of main causes of death among women around the world, affecting into both high-income and middle-income countries. Aim of Study: is to assess the relationship between cancer and age group among female participants. Methods: A cross-sectional study was...

Open access Research Article 10.9734/irjo/2025/v8i1178

Impact of Dietary Phytoestrogens on the Prevention and Management of Breast Cancer: A Comprehensive Analysis

Swastika Chatterjee, Harsahaj Singh Wilkhoo & Diana Rose · International Research Journal of Oncology · 2025

Breast cancer remains one of the most common cancers affecting women worldwide. Diet, particularly phytoestrogens—plant-derived substances with estrogen-like activity—has received increased interest in the prevention and treatment of breast cancer. This review thoroughly investig...

Open access Research Article 10.9734/irjo/2025/v8i1177

Pancreaticoduodenectomy: The Ibadan Experience

Ayandipo O.O, Idowu O.K, Afolabi A.O, Ajagbe O.A, Adeleye J.O, Fakoya A J, Dada O.E, Ilori O.T, Afuwape O.O, Ogundiran T.O & Irabor D.O · International Research Journal of Oncology · 2025

Introduction: Pancreaticoduodenectomy (PD), has become a procedure which has has evolved from a complex, staged operation with high morbidity and mortality to a routine single-session surgery. Methods: This longitudinal descriptive study at the Surgical Department of University C...

Open access Research Article 10.9734/irjo/2025/v8i1176

Subglottic Plasmacytoma as an Extramedullary Relapse of Multiple Myeloma: A Case Report

Karima Ouardi, J.E. Oubenjah, Sakina Elkhaoua, Saloua Ouraini, Bouchaib Hemmaoui, Fouad Benariba & Noureddine Errami · International Research Journal of Oncology · 2025

Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm arising outside the bone marrow and represents a minority of plasma cell disorders. EMP predominantly occurs in the head and neck region, with laryngeal involvement being exceedingly rare. Subglottic plasmacytoma is...

Open access Research Article 10.9734/irjo/2025/v8i1175

Barriers to Cervical Cancer Screening: An Assessment of the Knowledge, Attitude and Practice of Non-Medical Students of Ebonyi State University, Nigeria

Nwafor N. Bafford, Orji N. Jim, Obi M. Adaobi, Anyanwu Prisca. I, Alo Stephen N., Utah Francisca U., Okpata F. Chileka, Akaje Salamat A., Akuma G. Onyinyechi, Okafor Peace O., Keke Chukwuemeka O., Okorie I. Valerie, Nwakpa F. Nnabuife, Onu S. Ngozi & Akhaine J. Precious · International Research Journal of Oncology · 2025

Background: Cervical cancer primarily develops as a result of a persistent infection with high-risk types of the human papillomavirus (HPV). It can affect women at any stage during their reproductive years and it has been observed over time that most women that are not medically...

Open access Research Article 10.9734/irjo/2025/v8i1174