Arinze Anthony Onwuegbuna, Akunne Ijeoma Apakama, Emeka Akujuobi Chianakwalam, Chidiebele Malachy Ezeude, Bernard Chukwunonyerem Ochiogu, Anthonia Chinyelu Udeaja, Chisom God’swill Chigbo, Chidebe Christian Anikwe, Nworah Josiah Azubike Obiechina & George Uchenna Eleje·International Research Journal of Oncology·2024
Background: Retinoblastoma is a rare, curable but deadly intra ocular tumor affecting usually children under 5 years of age. Awareness, early detection and treatment determine vision preservation and patient’s survival. In low- and middle-income countries majority of children pre...
Aim: This study explored the sexuality-related lived experiences of women diagnosed with breast cancer during multimodal breast cancer treatment. Study Design: Qualitative exploratory descriptive design. Place and Duration of Study: Participants were recruited from the Oncology D...
Background: PIM1 kinase is a serine/threonine kinase known for its excessive production in various human cancers, particularly prostate cancer. This enzyme promotes prostate cancer development by adding phosphate groups to cellular components, preventing programmed cell death (ap...
The burden of lung cancer in Nigeria represents a significant clinical problem due to the high mortality rate. Added to this is the lack of a comprehensive cancer treatment strategy in Nigeria, resulting in underdiagnosis and poor access to treatment. Furthermore, the challenges...
Roy’lagbaja Fateemah Adekemi (Adebayo), Afolalu Olamide O., Olanrewaju John Adedayo, Alamu Sunday Olagbemiro & Amoo Olakunle M.·International Research Journal of Oncology·2024
Cervical cancer remains a leading cause of death among females in the developing country with poor prognosis attributed to lack of awareness about the disease and its prevention. This study sought to assess the uptake of cervical cancer screening service and associated factors am...
Ibrahim Bakhit Y. Elemam, Eman Abd elgadir M. Elshariff, Mohammed Abdelgader Elsheikh, Tibyan Abd Almajed Altaher, Ghanem Mohammed Mahjaf, Waha Ismail Yahia Abdelmula & Babbiker Mohammed Taher Gorish·International Research Journal of Oncology·2024
Background: Ovarian cancer is a deadly illness with little understanding of its biology. The tumor suppressor p63 is a homolog gene of p53. P63 has an important role in the development and differentiation of reproductive epithelium and interacts with p53 in human tumorigenesis. ...
Sheudeen Abubakar Abiola, Adline E. Ben-Chioma, Beega Godae Fidelis, Simeon Christopher Aloy, Anthony Augustine U. & Ibioku Elekima·International Research Journal of Oncology·2024
Breast cancer, a complex and heterogeneous disease, remains a leading cause of global cancer-related morbidity and mortality. According to the World Health Organization 2020 report, breast cancer is responsible for over 685,000 deaths. This comprehensive review explores epigeneti...
Aim: This study was a cross sectional study aimed at evaluating the concentration of the enzyme aromatase in premenopausal and postmenopausal women in Port Harcourt. Study Design: The study population comprised of apparently healthy premenopausal and postmenopausal women who were...
The homeobox (HOX) genes encode highly conserved, homeodomain-containing transcriptional factors that play a central role in embryonic development and the maintenance of cellular identity crucial to the differentiation of adult stem cells. Implicitly, the pathophysiological relev...
A right approach is essential to solve any illness. Cancer mortality remains at historic high and is still on the way to increase. The objective of this study is to find a right approach of cancer therapy to bring cancer mortality down. Myelodysplastic syndromes are diseases attr...
Cancer mortality is very high and is still increasing. The objective of this study is to rely on the restoration of chemo-surveillance to reduce cancer mortality called for by President Biden in his cancer moonshot initiative speech last year. The reason cancer mortality remains...
Breast cancer has been one of the most widespread cancer types in women worldwide. Breast cancer can be treated when detected early; otherwise, it has one of the highest mortality rates among cancer types. Many tools can be used for detection, but computer-based diagnosis systems...
Aims: This study aimed to investigate the effects of HIV infection and occupational exposure on the concentrations of selected toxic metals and essential trace elements such as zinc in relation to the carcinogenic process. Study Design: Comparative cross-sectional study. Place an...
Extravasation accidents involving vesicant chemotherapy products can lead to severe local tissue damage and long-term functional impairment. Intramuscular (IM) extravasation is particularly concerning due to potential deep tissue damage and limited accessibility for treatment. We...
This paper focuses on the relationship between HIF1A expression and the warburg effect. Considering that the warburg effect is a hallmark of cancer, it’s possible that it could be caused by a common mechanism within tumor microenvironments. This paper considers the common cause o...