Background: This study evaluated the neuroprotective effects of Bryophyllum pinnatum (B. pinnatum) in ketamine-induced neurotoxicity in Wistar rats, focusing on neurochemical and oxidative stress markers, as well as histological changes in the hippocampus and cerebral cortex. Met...
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Research Article10.9734/indj/2024/v21i6452
Genetics and epigenetics play critical roles in mental health, offering insights into the complex interplay between biological predisposition and environmental influences in the development and progression of mental disorders. Genetic studies have identified numerous risk loci as...
Open access
Research Article10.9734/indj/2024/v21i6451
This study critically evaluates the effectiveness of public health policies and programs targeting Alzheimer's and dementia care in the United States, with a specific emphasis on early detection, disparities in access to care, and variations in service quality between urban and r...
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Research Article10.9734/indj/2024/v21i5450
Neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), pose significant challenges to global healthcare systems due to their progressive nature and limited therapeutic options. In recent years, natural compounds h...
Open access
Research Article10.9734/indj/2024/v21i5449
Aims: This study aims to investigate the potential therapeutic effects and mechanisms of cannabidiol (CBD) in the treatment of Parkinson's disease (PD). Specifically, it focuses on understanding the role of CBD in managing motor and non-motor symptoms and its neuroprotective prop...
Open access
Research Article10.9734/indj/2024/v21i5448
Introduction: Chronic exposure of MDMA in humans has been shown to produce negative neuroplastic alterations to the brain's white matter and microvasculature, as well as significant neurodegeneration in the striatal, hippocampal, prefrontal, and occipital serotonergic axon termin...
Open access
Research Article10.9734/indj/2024/v21i5447
This research work investigated modulatory effects of Bryophylum pinnatum extract on BDNF expression, and cognitive functions in repetitive pain-induced oxidative stress in Wistar rats. Animals weighing between 80–100g were acquired from the animal house of the Department of Huma...
Open access
Research Article10.9734/indj/2024/v21i5446
Mental health services in Nigeria consists mainly of large government psychiatric hospitals. There are eight Neuropsychiatric hospitals and a similar number of teaching hospital psychiatric departments for a population of 200 million people. There is only one private community re...
Open access
Research Article10.9734/indj/2024/v21i5445
Background: Deaths by COVID-19 have left behind nearly 12 million recent bereaved individuals worldwide and researchers have raised concerns that the circumstances of COVID-19 related deaths will lead to a rise in prevalence of prolonged grief disorder (PGD) cases. Nevertheless,...
Open access
Research Article10.9734/indj/2024/v21i5444
Gilmar Dantas De Souza Filho, Henrique Almeida Assis Costa, Danielle Araújo Borsari, Erasmo Carlos Braulino, Plínio Regino Magalhães, Pericles Cristiano Batista Flores, Solange Aparecida Caetano, Elaine Aparecida Leoni, Thaisa Silva de Sousa & Marco Aurélio Aparecido Lucio·International Neuropsychiatric Disease Journal·2024
The consumption of alcoholic beverages by pregnant women poses a significant risk of harming the fetus, leading to permanent and irreversible physical, cognitive, and behavioral alterations. It can manifest as Fetal Alcohol Syndrome or Fetal Alcohol Effect, impair fetal developme...
Open access
Research Article10.9734/indj/2024/v21i4443
The disease known as bulimia nervosa, which is typified by purging and binge eating, usually starts in adolescence and peaks at the age of 18. The ratio of female to male patients varies from 10:1 to 20:1, with a lifetime frequency of 3 per cent. The majority of bulimic individua...
Open access
Research Article10.9734/indj/2024/v21i4442
Kaynara Trevisan, Renata Cristina-Pereira, Breno Régis Santos, Paulo Eduardo Mendonça, Heberson Teixeira da Silva, Maria Tereza Gonçalves-Mendes & Tales Alexandre Aversi-Ferreira·International Neuropsychiatric Disease Journal·2024
Aims: This review aims to perform an extensive literature search about the pesticides problems and to associate with AD in qualitative analysis, mainly. Place and Duration of Study: Biomathematics Laboratory, Institute of Biomedical Sciences, Federal University of Alfenas, Alfena...
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Research Article10.9734/indj/2024/v21i4441
Renata Cristina-Pereira, Anna Luiza de Araújo Ribeiro, Anna Cláudia Ferreira Nunes, Luca Casale Guereschi, Maria Amália Garcia da Silveira Araújo, Maria Tereza Gonçalves-Mendes, Kaynara Trevisan, Heberson Teixeira da Silva & Tales Alexandre Aversi-Ferreira·International Neuropsychiatric Disease Journal·2024
Aims: The main aim of this study was to use specific data from the literature on ageing, correlating this with the pesticide contamination, in order to understand the relationship with an increasingly ageing population. Study Design: A systematic review was performed. Place and D...
Open access
Research Article10.9734/indj/2024/v21i4440
Aims: to explore the time that crammer start to study and the time of exam being held and relate this two with the result of the remedial exams which conducted electronically (computer based). Study Design: simple descriptive cross sectional study Place and Duration of Study: c...
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Research Article10.9734/indj/2024/v21i4438
Mental health refers to a person's emotional, psychological, and social well-being, which encompasses aspects such as thoughts, feelings, behaviors, and the ability to cope with life's challenges. Several factors including drug abuse have been recognized to cause mental health di...
Open access
Research Article10.9734/indj/2024/v21i4439