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All published articles 370

Assessment of Quality of Life of Cervical Cancer Patients Using ECOG-Performance Status Scale

Shubham Lingappanoor, Geetha Rani Manupati, Vasthalya Meesala, Padma Yaragani, Brahmani Bachu & Shyam Sunder Anchuri · Journal of Cancer and Tumor International · 2019

Background: Cervical cancer is becoming one of the emerging health burdens for womenhood and India accounts for one-third of the cervical cancer deaths globally. More than 80% of women with cervical cancer are diagnosed at an advanced stage. In this study, we aimed to assess the...

Open access Research Article 10.9734/jcti/2019/v9i330108

Body Mass Index and Age Correlation with Prostate-specific Antigen Density as Prostate Cancer Risk Indicators in a Screened Male University Population in Nigeria: A Pilot Study

Eyam Sunday Eyam, Ima-Abasi E. Bassey, Edoise M. Isiwele & Eyam Lilian Eberechukwu · Journal of Cancer and Tumor International · 2019

Background: Prostate-specific antigen density (PSAD) is one of the means of improving PSA sensitivity as a marker of a prostate cancer diagnosis. However, this ability is perceived to be obscured by certain factors such as high body mass index and age in Caucasian and western pop...

Open access Research Article 10.9734/jcti/2019/v9i330107

Immunomodulatory Fungi: An Alternative for the Treatment of Cancer

Diana Lorena Nieto-Mosquera, Hugo Ramiro Segura-Puello, Juan Sebastián Segura-Charry, Diana Milena Muñoz-Forero & Andrea Catalina Villamil-Ballesteros · Journal of Cancer and Tumor International · 2019

The present study aims to determine the role of immunomodulatory fungi for the treatment of cancer as an alternative way. Mushrooms have been part of human culture for thousands of years, many cultures especially from the East, recognized that the extracts of certain fungi could...

Open access Research Article 10.9734/jcti/2019/v9i230106

Proportions of Pre-Cancerous Cervical Lesions and Its Associated Factors among Women Clients in the Age Group of 30-49yrs in Gynecology Ward of Dessie Referral Hospital and FGAE, North-East Ethiopia, 2016

Kibir Temesgen, Amare Workie, Tenagnework Dilnessa & Mengistu Abate · Journal of Cancer and Tumor International · 2019

Introduction: Globally, cervical cancer is the second most common cancer in women; in 2008 there were an estimated 530,000 new cases and more than 270,000 women die from it [1]. In Ethiopia, cervical cancer is the second most common cancer following breast cancer and the leading...

Open access Research Article 10.9734/jcti/2019/v9i230105

The Effect of Chemotherapy on Clinical, Haematological and Biochemical Profile in Breast Cancer Patients Undergoing Chemotherapy at Cape Coast Teaching Hospital; A Longitudinal Study

Rebecca Peniel Storph, Frank N. Ghartey, Richard K. D. Ephraim, Enoch Mensah, Martin Mornah, Linda Ahenkorah-Fondjo, David L. Simpong, Charlotte Addai, Bright Kobena Segu Domson, Joseph Benjamin Baidoo & Patrick Adu · Journal of Cancer and Tumor International · 2019

Background: People with primary invasive breast cancer receive both local (surgery and radiation therapy) and systemic treatment (chemotherapy and hormonal therapy). However, there are substantial short-and long-term side effects from chemotherapy as documented in several studies...

Open access Research Article 10.9734/jcti/2019/v9i230104

Changing Histopathological Pattern of Paediatric Malignant Tumours Seen at the Jos University Teaching Hospital, North-Central, Nigeria

Daniel Yakubu, Innocent Emmanuel, Jagshak Barnabas Mandong & Mandong Barnabas Mafala · Journal of Cancer and Tumor International · 2019

Background: Childhood cancer is attracting public health attention in Sub-Saharan Africa because of its’ increasing contribution to morbidity and mortality, and the changing pattern in relative frequency and diagnostic challenges in resources poor settings. The objective of the s...

Open access Research Article 10.9734/jcti/2019/v9i230103

Role of Midkine in Predicting Malignancy in Patient with Solitary Thyroid Nodule

Nesma A. Ibrahim & Ahmed M. Hamam · Journal of Cancer and Tumor International · 2019

Background: Solitary thyroid nodules are a common clinical problem. None of sonographic features is sufficient to discard or detect malignancy efficiently. Midkine is a novel heparin-binding growth factor, plays critical roles in carcinogenesis. In this study, we aimed to evaluat...

Open access Research Article 10.9734/jcti/2019/v9i230102

Metronomic Low Dose Leucovorin- Fluorouracil versus Supportive Treatment for Patients with Recurrent or Metastatic Colorectal Cancer

Hend M. Hamdey Rashed Elkalla, Mohamed Saad Elzahy & Shoukri Hassan Elazab · Journal of Cancer and Tumor International · 2019

Introduction: There was an improvement in therapeutic regimens for advanced colorectal cancer (CRC) in the last few decades. The low dose metronomic palliative chemotherapy in patients with advanced CRC after the failure of standard chemotherapy led to a dramatic increase in effi...

Open access Research Article 10.9734/jcti/2019/v9i130101

Hypofractionation in Breast Cancer - A Retrospective Study in a Tribal Population Based Medical College in West Bengal, India

Santanu Acharyya, Bidisha Ghosh & Satadru Biswas · Journal of Cancer and Tumor International · 2019

Introduction: In a tribal population based area in West Bengal, India though carcinoma cervix is the commonest malignancy in female patients, yet apart from that carcinoma breast is also increasing in number in the recent years. Breast cancer accounts for approximately 26.6% of f...

Open access Research Article 10.9734/jcti/2019/v9i130100

Diagnostic Significance of Beclin-1 and Transforming Growth Factor β in Breast Cancer

Shereen Saeid Mahmoud Elshaer, Laila Ahmed Rashed & Mona Mohammed Abdel Hamid · Journal of Cancer and Tumor International · 2019

Background: The main cause of cancer deaths amongst women breast cancer remains a clinical and social challenge, and a serious public health problem. On a worldwide level, it continues to be a devastating disorder.BECN1  is  a  tumor  suppressor  gene  implicated  in  the  initia...

Open access Research Article 10.9734/jcti/2019/v9i130099

Overexpression of Epidermal Growth Factor Receptor (EGFR) in Esophageal Squamous Cell Carcinoma and Its Correlation with Clinicopathological Characteristics in Central Uganda

Asafu M. Munema, James J. Yahaya, Robert Lukande & Sam Kalungi · Journal of Cancer and Tumor International · 2019

Aims: The aims of the current study were to determine the prevalence of epidermal growth factor (EGFR) receptor in patients diagnosed with esophageal squamous cell carcinoma (ESCC) as well as assessing the correlation of overexpression of EGFR with age, gender and tumor grades of...

Open access Research Article 10.9734/jcti/2019/v9i130098

Role of Immunohistochemistry in Diagnosis of Papillary Thyroid Carcinoma: The Use of Ck19, CD56, P63 and CD117

Azza Abdel-Aziz & Dina Abdallah · Journal of Cancer and Tumor International · 2019

Objective: Papillary thyroid carcinoma (PTC) is the most frequent histologic type of all thyroid malignancies. The presence of characteristic nuclear changes focally in a thyroid lesion may cause diagnostic dilemma. Immunohistochemistry may be helpful in the diagnosis of PTC yet...

Open access Research Article 10.9734/jcti/2019/v9i130097

Technological Applications in Skin Cancer Prevention

Jennings Hernandez & Anjali Kumar · Journal of Cancer and Tumor International · 2019

In the United States, skin cancer is the most common cancer diagnosed. The three types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Of those, basal and squamous cell carcinomas are the most diagnosed skin cancer types. Both of which are curable,...

Open access Research Article 10.9734/jcti/2018/v8i230096

Autoimmune Haemolytic Anaemia in Patients with Cancer Diagnoses

Kaladada Ibitrokoemi Korubo, Oseikheumen Adebayo Ejele & Chijioke Adonye Nwauche · Journal of Cancer and Tumor International · 2019

Aims: To determine if AIHA plays a role in anaemia associated with malignancies, and ascertain the cancers in which AIHA occurs. Study Design: This was a cross-sectional case-control study. Place and Duration of Study: Department of Haematology and Blood Transfusion, University o...

Open access Research Article 10.9734/jcti/2018/v8i230095

Retinoblastoma – Lessons Learned about Patterns of Care and Contributory Factors from 5 Years’ Experience in a Tertiary Care Center in Eastern India

Debjit Ghosh, Bidyut Mondal, Abhishek Basu, Janmenjoy Mondal & Shubhendu Gangopadhyay · Journal of Cancer and Tumor International · 2019

Objectives: Retinoblastoma is the most common intraocular malignancy afflicting children worldwide. Even though there are enough data about the epidemiology of retinoblastoma in western population, there are only few reports from developing countries like India. In this retrospec...

Open access Research Article 10.9734/jcti/2018/v8i230093