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All published articles 370

Right Sided Colonic Tumour a Cause of Unexplained Anaemia in Adults: Need for Increased Awareness and Colonic Examination in Adult Patients with Unexplained Anaemia-A Case Series

Victor Wagozie & Anaero-nweke Stephen Chigozie · Journal of Cancer and Tumor International · 2026

Background: Colorectal cancer is the fourth most common cancer and the second largest cause of cancer mortality in the United Kingdom. According to World Health Organization, there were 1.8 million new cases and almost 861,000 deaths in 2018, globally. In United Kingdom over 42,0...

Open access Research Article 10.9734/jcti/2026/v16i2356

Awareness, Knowledge, and Perceived Barriers toward Colorectal Cancer Screening among Outpatients in Southern Nigeria: An Exploratory Pilot Study

Victor Wagozie & Nukpegabari Ambassador · Journal of Cancer and Tumor International · 2026

Background: Colorectal cancer (CRC) poses an escalating public health challenge in Nigeria, characterised by late-stage clinical presentations and high mortality rates. While screening remains the most effective intervention for mitigating disease progression, national uptake rem...

Open access Research Article 10.9734/jcti/2026/v16i2355

Bridging the Gap between AI Performance and Clinical Practice: A Comprehensive Scoping Review of Breast Cancer Diagnosis

Muhammed Besiru Jibrin, Sulaiman Yusuf Ali, Albashir Ahmad, Suleman Mohammad Gidado, Aisha Muhammed Bose Ahmed & Usman Idris Ismail · Journal of Cancer and Tumor International · 2026

Breast cancer remains a leading cause of mortality among women worldwide, necessitating early and accurate diagnosis. Recent advancements in artificial intelligence (AI), particularly machine learning and deep learning, have shown significant potential in improving diagnostic per...

Open access Research Article 10.9734/jcti/2026/v16i2354

Knowledge and Uptake of Cervical Cancer Screening among Women Attending Selected Churches in Umuahia South LGA, Abia State, Nigeria

Uka-Kalu, Ezinne Chioma & Tasie Binta Tochi · Journal of Cancer and Tumor International · 2026

Background: Cervical cancer remains a leading cause of cancer-related mortality among women in Nigeria, despite the availability of effective screening. While broader studies in Nigeria have identified general barriers and facilitators, there is limited evidence on actual screeni...

Open access Research Article 10.9734/jcti/2026/v16i2353

Successful Management of Dilated Intrahepatic and Extrahepatic Ducts in Adenocarcinoma of the Pancreatic Head: A Case Report

A. E. Ben-Chioma, I. Elekima, D. O. Onwuli & O. I. Alatise · Journal of Cancer and Tumor International · 2026

More than 90% of cases of pancreatic cancer are adenocarcinomas, making them the most prevalent gastrointestinal cancer disease. This cancer develops in the pancreatic duct lining. Adenocarcinoma may also arise from the cells that produce pancreatic enzymes. The features of adeno...

Open access Research Article 10.9734/jcti/2026/v16i2352

Paget’s Disease of the Breast with Underlying Invasive Ductal Carcinoma in a 64-Year-Old Woman: A Case Report

Victor Wagozie & Okigbeye Danagogo · Journal of Cancer and Tumor International · 2026

Introduction: Paget’s disease of the breast is a rare manifestation of breast carcinoma involving the nipple–areolar complex and accounts for approximately 1–4% of all breast cancers (Chen et al., 2006). It is frequently associated with underlying ductal carcinoma in situ (DCIS)...

Open access Research Article 10.9734/jcti/2026/v16i2351

Advances in Imaging Biomarkers for Oncology: A Comprehensive Review of Techniques, Clinical Applications and Future Perspectives

Kasib Zafar, Mariam Jamila & Mohd Rahil · Journal of Cancer and Tumor International · 2026

Imaging biomarkers are important for modern oncology as it provide quantitative ways to assess tumour functioning, monitoring, progression, and evaluate response to treatment. There are several methods are available for diagnosis of tumour such as CT and MRI based techniques; bio...

Open access Research Article 10.9734/jcti/2026/v16i2350

A Review on the Protective Effects of Vitamin D\(_3\) and It's Analog against Hepatocellular Carcinoma, in vivo and in vitro

Debasmita Ghosh, Sarmistha Banik & Sujit Kumar Bhowal · Journal of Cancer and Tumor International · 2026

Hepatocellular carcinoma (HCC) has significant gender differences in incidence and prognosis, indicating the sex-specific pathogenic process. Vitamin D3, aside from its traditional function in calcium homeostasis, has pleiotropic actions with possible anti-cancer effects. This re...

Open access Research Article 10.9734/jcti/2026/v16i2349

Immune Editing of Stem Cell Fate: Implications for Cancer Initiation and Therapy Resistance

Dickens Agie & Michael Sakha · Journal of Cancer and Tumor International · 2026

Stem cell fate has traditionally been viewed as a product of intrinsic transcriptional programs and epigenetic regulation operating within specialized tissue niches. However, growing evidence suggests that immune-derived signals constitute a powerful and underappreciated force sh...

Open access Research Article 10.9734/jcti/2026/v16i2348

Harnessing the Hippocratic Fire: The Role and Comprehensive Consolidation of HITHOC in Pleural Malignancy Management

Swarnava Chanda, Abdul Quadir Rahmani & Dhairya Gupta · Journal of Cancer and Tumor International · 2026

Hyperthermic intrathoracic chemotherapy (HITHOC) has emerged as a significant multimodal therapeutic adjunct for the management of aggressive pleural malignancies, primarily malignant pleural mesothelioma and stage IVA thymoma. By combining surgical cytoreduction with the local a...

Open access Research Article 10.9734/jcti/2026/v16i2347

Impact of Maintenance Therapy with Capecitabine vs Observation in Triple-Negative Breast Cancer

Mohamed. S. Zahi, Shokry. H. El-Azab & Sherif. M. El-Hadidy · Journal of Cancer and Tumor International · 2026

Background: Triple-negative breast cancer (TNBC) is a great challenge in modern oncology due aggressive biological behavior. Chemotherapy is the only treatment option for those patients. This rises the idea of using capecitabine as maintenance therapies to reduce the risk of rela...

Open access Research Article 10.9734/jcti/2026/v16i1346

From Bench to Bedside: Structural and Biological Barriers to Therapeutic Translation in Pancreatic Cancer

Reginald Oyortey, Tosin Abiodun Aderanti, Ngwoke, Chinaza Faith, Esosa Omoregie, Anointing Akindele, Salifu Faisal & Bethel Abioke Uchechukwu · Journal of Cancer and Tumor International · 2026

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, driven largely by KRAS mutations and profound therapeutic resistance. This review summarizes recent translational strategies aimed at bridging laboratory discoveries with clinical application, including...

Open access Research Article 10.9734/jcti/2026/v16i1345

The Evolutionary Landscape of Inflammatory and Nutritional Biomarkers in Oral Squamous Cell Carcinoma: A Comprehensive Review of Pathogenesis and Prognosis

Swarnava Chanda & Abdul Quadir Rahmani · Journal of Cancer and Tumor International · 2026

Oral squamous cell carcinoma (OSCC) is a major health burden with a disproportionately high incidence in regions such as India due to cultural habits like tobacco and betel nut chewing. Despite significant therapeutic advancements, low overall survival rates are encountered in ad...

Open access Research Article 10.9734/jcti/2026/v16i1344

External Beam Radiation Therapy in Mediastinal Metastasis of Radioiodine-Refractory Papillary Thyroid Carcinoma: A Case Report

Christine T.U. Banjarnahor & Matthew N. Ruslim · Journal of Cancer and Tumor International · 2026

External beam radiation therapy (EBRT) for mediastinal metastasis of papillary thyroid carcinoma is challenging because of the radioresistance of the cancer cells and surrounding vital organs. A 45 year-old male was diagnosed with mediastinal metastasis of refractory papillary th...

Open access Research Article 10.9734/jcti/2026/v16i1343

From Blood to Biomarkers: Liquid Biopsy as a Tool in Precision Oncology

Donatus Onukwufor Onwuli, Uchechukwu Achor Obisike & Adline Erinma Ben-Chioma · Journal of Cancer and Tumor International · 2026

Precision oncology relies on accurate, timely, and minimally invasive approaches to detect and monitor cancer. Traditional tissue biopsies are invasive and often fail to capture tumour heterogeneity or allow repeated sampling. Liquid biopsy has emerged as a promising alternative...

Open access Research Article 10.9734/jcti/2026/v16i1342