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All published articles 370

Flavonoids, Breast Cancer Prevention, and Its Treatment: A Growing Evidence

Md. Rubel Akanda, Sadia Jafrin, Shah Ashadul Islam, Shakir Hosen, Md. Mariful Islam, Nazmul Islam & Habibul Bari Shozib · Journal of Cancer and Tumor International · 2025

There is mounting evidence linking certain lifestyle factors such as food, weight, and physical activity to an increased risk of breast cancer. Flavonoids are commonly used in traditional medicine. Plenty of studies have investigated the relationship between flavonoid consumption...

Open access Research Article 10.9734/jcti/2025/v15i1281

The Role of Bioelectric Signals in Cancer Genome Regulation and Potential Therapeutic Implication: An Overview

Lawrence John AJutor, Fatima Bello Sani, Elijah Nehemiah Kama, Kingsley Ugonna Ugoagwu, Adegbesan Abiodun Christopher, Daniel Temiloluwa Oyedemi, Peter Bemigho Adewoyin, Olayinka Esther Agbetanmije, Adepeju Matilda Adekoya & Erere Godsent Onyeugbo · Journal of Cancer and Tumor International · 2025

Bioelectrical signals which are directed by ion channels and membrane potential (V_mem), play a crucial role in many cellular processes including proliferation and differentiation. It has also been known to influence processes such as gene expression, epigenetics, and tumor progr...

Open access Research Article 10.9734/jcti/2025/v15i1280

Importance of Glomerular Filtration Rate Determination and its Role in Drug-Dose Adjustments with Special Reference to Oncology

Brian Churchill, Ekaterina Vorozheikina, Anastasiya Vyshenskaya, Cecilia Sison & Luis Mendoza · Journal of Cancer and Tumor International · 2025

Glomerular filtration Rate (GFR) measured in steady state is the best marker of kidney function. Glomerular filtration rate can be determined using exogenous markers like inulin, iothalamate, or iohexol (mGFR), or estimated using endogenous markers like creatinine and cystatin C...

Open access Research Article 10.9734/jcti/2025/v15i1279

Inverted Papilloma of the Bulla Ethmoidalis: An Uncommon Epicenter for a Benign Yet Aggressive Tumor

Ainin Zahidah Binti Kamal Zuhairi & Khairul Azhar Bin M. Rajet · Journal of Cancer and Tumor International · 2025

Inverted papillomas are benign tumours known for their locally aggressive behaviour, characterised by local tissue destruction, a high tendency to recur if resection is incomplete, and a risk of carcinomatous evolution into squamous cell carcinoma. Although most cases arise from...

Open access Research Article 10.9734/jcti/2025/v15i1278

Expression Patterns of ER, PR, Her2/neu, and Ki67 in Sudanese Breast Cancer Patients

Tumadir Mohamed Adam Ali, Mohamed Mahgoub Hassan Khalifa, Ahmed Abdalla Agab Eldour, Sirelkhatim Merghani Elkheir Mohammed & Hussain Gadelkarim Ahmed · Journal of Cancer and Tumor International · 2024

Background: Tumor markers are crucial indicators for breast cancer treatment and follow-up. Thus, this study attempted to explore the expression patterns of ER, PR, Her2/neu, and Ki67 in Sudanese breast cancer patients. Methodology: This study was a retrospective descriptive anal...

Open access Research Article 10.9734/jcti/2024/v14i4277

Emerging Molecular and Clinical Challenges in Managing Lung Cancer Treatment during the Covid-19 Infection

Sandhya Shukla, Navin Ray, Arvind Kumar Shukla, Adarsha Mahendra Upadhyay, Giovanna Mirone & Raj Kumar Mongre · Journal of Cancer and Tumor International · 2024

The COVID-19 pandemic now had a broad impact on the health care system since its start. Cancer patients, specifically lung cancer patients, are undergoing a more vulnerable group due to their complex pathophysiological and immunological characteristics. Therefore, they need more...

Open access Research Article 10.9734/jcti/2024/v14i4276

Adamantinoma-like Ewing Sarcoma: A Report of Two Rare Cases in the Pancreatic Tail and Spine

Shaikhali Barodawala, Gayatri Soneta, Kirti Chadha, Gauri Pradhan, Pooja Parab & Shibani Ramchandran · Journal of Cancer and Tumor International · 2024

Adamantinoma-like Ewing sarcoma (ALES), an extremely rare variant of Ewings sarcoma occurs primarily in the head and neck sites. ALES is characterized by basaloid cytomorphology, immunohistochemically expresses keratins, p63, p40, CD99, and harbors t (11; 22) EWSR1::FLI1 transloc...

Open access Research Article 10.9734/jcti/2024/v14i4275

Chondroblastic Osteosarcoma of the Mandible: An Uncommon Site for Osteosarcoma

Walter Lim Yung Chwen, Asmah Hanim Bt Hamdan, Nurul Aifa Binti Zahari, Intan Bazilah Binti Abu Bakar & Azwan Halim Abdul Wahab · Journal of Cancer and Tumor International · 2024

Osteosarcoma is one of the most common types of malignant bone tumors, typically involving long bones such as the femur, tibia, and humerus. However, osteosarcomas occurring in the jaws are exceptionally rare, accounting for approximately 7% of all osteosarcoma cases and just 1%...

Open access Research Article 10.9734/jcti/2024/v14i4274

Spectrum of Gastric Carcinoma in a Tertiary Care Centre with Special Reference to PDL1 and Cyciln D1

Binata Bandopadhyay, Madhumita Mukhopadhyay, Chhanda Das, Abhishek Dutta, Subhamoy Saha & Biswanath Mukhopadhyay · Journal of Cancer and Tumor International · 2024

Introduction: Gastric carcinoma is the fifth most frequently diagnosed tumor and the fourth leading cause of death. They represent a heterogenous group of tumors with multifactorial etiologies, both environmental and genetic. PD-L1 is a transmembrane protein, and a positive PD-L1...

Open access Research Article 10.9734/jcti/2024/v14i4273

Nephroblastoma in a Nigerian Newborn: A Case of a Common Kidney Tumour in an Uncommon Age Group

Bassey, EU, Nnoli C, Hanny JO & Ikpeme, EE. · Journal of Cancer and Tumor International · 2024

Nephroblastoma (Wilm’s Tumour) is the commonest paediatric renal cancer worldwide. It is uncommon in infants less than six months of age and very rarely seen in neonates.  The uncommon presentation of nephroblastoma in the newborn period of this two month old, depicts the possibi...

Open access Research Article 10.9734/jcti/2024/v14i4272

A Case Report on Congenital Mesoblastic Nephroma

Rico Alfredo Hutabarat, Ibnu Sina Ibrohim, Mohammad Ilham Akbar Ali & Johanna Elisha · Journal of Cancer and Tumor International · 2024

Aims: This study aims to provide a comprehensive review of the epidemiology, genetic underpinnings, clinical presentation, and management strategies of congenital mesoblastic nephroma (CMN), with a focus on the diagnostic and therapeutic challenges that distinguish it from other...

Open access Research Article 10.9734/jcti/2024/v14i4271

Immunohistochemical Analysis of Tumor Suppressor p53 in p-Dimethylamino Benzaldehyde (DMBA) Induced Hepatocarcinogenesis in Rats (Rattus norvegicus L.) Male Wistar Strains

Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani, IGusti Ayu Artini, Desak Ketut Ernawati, I. Gusti Made Gede Surya Candra Trapika, Ni Putu Sriwidyani & I Gusti Kamasan Nyoman Arijana · Journal of Cancer and Tumor International · 2024

Aims: Hepatocellular carcinoma accounts for approximately 90% of all primary liver malignancies and poses a major global health challenge. The initiation of hepatocellular carcinoma (HCC) is marked by a progressive accumulation of molecular alterations, the origins of which remai...

Open access Research Article 10.9734/jcti/2024/v14i4269

The Role of Parenteral Nutrition in Cancer in Indian Settings

Kumar Prabhash, Arvind Krishnamurthy, Chandra Sekhar Puli, Saurabh Bhave, Shirish Alurkar, Shivshankar Timmanpyati, Shisir Shetty, Suvadip Chakrabarti, Tejinder Singh, Nandini Menon & Vanita Noronha · Journal of Cancer and Tumor International · 2024

Background: Almost 50% of patients with cancer suffer from malnutrition during their first hospital visit. However, it is often overlooked and undiagnosed and is associated with morbidity, mortality, poor tolerance to treatment, and treatment outcomes. Guidelines recommend suppor...

Open access Research Article 10.9734/jcti/2024/v14i4270

Conservative Decompression in the Management of Odontogenic Keratocysts: Case Report

João Francisco Barbosa Cordeiro, Rafael da Silva Vanolli, Bruna Caroline Ruthes de Souza, Nicolas Mazur, Gabriel Luiz Linn, Ricardo Augusto Conci, Eleonor Álvaro Garbin Júnior, Geraldo Luiz Griza & Natasha Magro Érnica · Journal of Cancer and Tumor International · 2024

Aims: This study aims to assess the effectiveness of decompression as a conservative treatment for odontogenic keratocysts (OKCs), with emphasis on reducing recurrence rates, decreasing lesion size, and preserving adjacent anatomical structures. Additionally, it explores the comb...

Open access Research Article 10.9734/jcti/2024/v14i4268

Effects of Chemotherapy on the Haematological Profile of Cervical Cancer Patients in Douala General and Laquintinie Hospitals

Emmanuel Acha Asongalem, Ebot Walter Ojong, Nji Diba Clovis, Moses Njutain Ngemenya, Alain Mefire Chichom & Forwah Jacques Ndeh · Journal of Cancer and Tumor International · 2024

Background: Cervical cancer is the second most diagnosed cancer and third leading cause of death from cancer among females in developing countries including Cameroon. Chemotherapy is a widely used treatment modality for this cancer, aimed at destroying cancerous cells and prevent...

Open access Research Article 10.9734/jcti/2024/v14i4267