Anisha Nallasamy, Manju Rajput, Zahid Ahmad Wani, Maryam Khazir Dar, Aakanksha, Sheikh Hibban Fayaz, Subiksha S & Naveen H Simon·Journal of Cancer and Tumor International·2024
Cancer immunotherapy has transformed cancer treatment by harnessing the immune system to recognize and eliminate cancer cells. Recent years have witnessed significant advancements in this field, including the development of immune checkpoint inhibitors, chimeric antigen receptor...
Open access
Research Article10.9734/jcti/2024/v14i2251
The combination of adjuvant Abemaciclib with endocrine therapy (ET) has emerged as a significant advancement in the management of HR+, HER2-, node-positive, high-risk early breast cancer, as demonstrated by the findings of the MonarchE trial. This innovative treatment approach yi...
Open access
Research Article10.9734/jcti/2024/v14i2250
Aim: Records have been reported on the inflicting attributes of cancer in society and how early detection is necessary for preventive measure and as a proactive step. The use of Magnetic Resonance Imaging (MRI) has been proved as an effective and proficient diagnostic method for...
Open access
Research Article10.9734/jcti/2024/v14i1249
Anti-PD-1 and anti-PD-L1 are therapies that have shown success in cancer treatment. However, while treating cancer with PD-1/PD-L1 blockade is similar, the clinical response rate is still low in certain cancers at around 40%. Therefore, therapeutic strategies are needed to increa...
Open access
Research Article10.9734/jcti/2024/v14i1248
Quiescent cancer stem cells (QCSC) are non-proliferating cells that survive in the G0 phase and have low ki-67 expression and high p27 expression. QCSCs have the ability to evade most chemotherapy, and some subsequent treatments may result in a higher proportion of quiescent canc...
Open access
Research Article10.9734/jcti/2024/v14i1247
Adipose-derived stem cells (ASC) are cells from the core of fat tissue that secrete various cytokines, growth factors, proteins and extracellular vesicles that can be used in regenerative therapy, especially in the case of cancer. This ASC produces a secretome which is an exosome...
Open access
Research Article10.9734/jcti/2024/v14i1244
Rushin Patel, Mrunal Patel, Zalak Patel, Himanshu Kavani, Afoma Onyechi, Jessica Ohemeng-Dapaah, Dhruvkumar Gadhiya, Darshil Patel & Chieh Yang·Journal of Cancer and Tumor International·2024
Objective: The objective of this study is to thoroughly investigate the use of artificial intelligence (AI) and machine learning (ML) techniques for diagnosing and predicting prognosis in gastric cancer, utilizing the latest available data. Methods: Following the Preferred Report...
Open access
Research Article10.9734/jcti/2024/v14i1241
Introduction: Cervical cancer is an important global health problem and, it is the fourth leading cause of cancer death among women worldwide. The distribution of cervical cancer differs across the world, with more than 85% of deaths occurring in developing regions. The incidence...
Open access
Research Article10.9734/jcti/2023/v13i3-4242
Introduction: Basal cell carcinoma (BCC) is the most common skin type cancer with an incidence rate of around 75-80%. The most common location is in the head and neck area around 70-80% and followed by other body parts around 25% consist of the penis, vulva or perianal area and 5...
Open access
Research Article10.9734/jcti/2023/v13i3-4243
Adipose-derived stem cells (ADSC) are a biological development that provides new hope regarding tissue engineering and regenerative therapy. Due to its potential paracrine activity, compounding, paracrine activity and immunomodulatory function, ADSC-based cell-assisted lipotransf...
Open access
Research Article10.9734/jcti/2023/v13i3-4245
Recently, nanomedicine has had a great impact on drug discovery and made the way for the drug delivery system for therapeutic utility. There are many nanoscale products increasing in the research field and in the medical sector. Nanoparticle modified drugs are being developed and...
Open access
Research Article10.9734/jcti/2023/v13i4246
Objective: The X-linked inhibitor of apoptosis protein (XIAP) immunohistochemical expression was employed to assess the anti-apoptotic activity of mucoepidermoid carcinoma (MEC) in relation to different clinicopathological variables to understand if XIAP immunoexpression could re...
Open access
Research Article10.9734/jcti/2023/v13i3-4240
Introduction: Neck lymphangioma is a benign congenital malformation that occurs frequently in children, and is rare in adults. They are usually found in the head and neck region and are often considered a metastatic lesion rather than a primary neoplasia. Most lymphangiomas are a...
Open access
Research Article10.9734/jcti/2023/v13i3239
Aims: Determine the potential role of h-TERT as a prognostic marker for oral squamous cell carcinoma by evaluating its immunohistochemical expression in different OSCC histologic grades in comparison with normal oral mucosa. Study Design: A retrospective study. Place and Duration...
Open access
Research Article10.9734/jcti/2023/v13i3237
Introduction: Myxofibrosarcoma (MFS) is a type of malignancy from the group of malignant fibrous histiocytoma. Myfxofibrosarcoma is a type of soft tissue neoplasm that is aggressive. The clinical symptoms are not pathognomonic and the histological picture is very heterogeneous, o...
Open access
Research Article10.9734/jcti/2023/v13i3238