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All published articles 239

Triple-negative Primary Myelofibrosis: A Diagnostic Challenge

J. Sakthivel, P. Dineshkumar, V. Prabhu, M. Lavanya & T. B. Uma Devi · International Journal of Research and Reports in Hematology · 2026

Primary myelofibrosis (PMF) is a BCR-ABL1-negative myeloproliferative neoplasm that may be diagnostically difficult when canonical driver mutations are absent. We report a male in his 30s with treated hypothyroidism who presented with low-grade intermittent fever and left-sided d...

Open access Research Article 10.9734/ijr2h/2026/v9i2226

Effect of Some Haematological, Haemostatic and Inflammatory Markers on Parity in Cervical Cancer Patients in Port Harcourt

Abiye Chiladi Isomah, Princess Nmerukini Ewhorlu & Chiladi Jeff Isomah · International Journal of Research and Reports in Hematology · 2026

Most cervical cancers are caused by Human Papillomavirus (HPV), the most common sexually transmitted infection that causes warts in various parts of the body.  Cervical cancer is the second common female malignant tumor globally that seriously threatens females’ health. This stud...

Open access Research Article 10.9734/ijr2h/2026/v9i2225

Silent Multiorgan Injury in Sickle Cell Disease: Redefining Mortality Beyond Pain Crises

Daniel Obinna Eke, Obiageri Ihuarulam Okeoma, Leo Tata, Salamah Abimbola Junaid, Williams Temidayo Solomon & Esther Uyoyooghene Olokede · International Journal of Research and Reports in Hematology · 2026

Sickle cell disease (SCD) has typically been seen through the prism of acute vaso-occlusive crises and other clinically noticeable issues that call for medical attention. The mortality rate among people with sickle cell disease (SCD) is still much higher than that of the general...

Open access Research Article 10.9734/ijr2h/2026/v9i2224

Broken Trephine Biopsy Needle: A Case Report of a Rare but Not Impossible Complication

Paxman Dandyson Uku, Emmanuel Wobo, Christine Abaiayam Dangana, Chinyere Eunice Eze, Eunice Belema & Ameh Samuel Ameh · International Journal of Research and Reports in Hematology · 2026

Background: Bone marrow aspiration and trephine biopsy are essential procedures in haematology  for the diagnosis, prognostication, and monitoring of a wide range of haematological disorders. Although generally safe, rare procedural complications may occur, including breakage of...

Open access Research Article 10.9734/ijr2h/2026/v9i2223

A Comparative Study on Platelet Indices in Women with Uterine Leiomyomas and Apparently Healthy Controls in Port Harcourt, Nigeria

Onengiye Livingstone Davies, Beauty E. Echonwere-Uwikor, Beatrice W. Moore-Igwe & Stella U. Ken-Ezihuo · International Journal of Research and Reports in Hematology · 2026

Alteration in coagulation parameters is one of the common occurrences in the pathology of many health conditions, including uterine fibroids. This study evaluated the levels of some platelet and coagulation in female subjects with uterine fibroids. The study involved 240 subjects...

Open access Research Article 10.9734/ijr2h/2026/v9i1222

From Uncertainty to Reality: Overcoming the Translational Gap in AI-interpreted Platelet Dynamics for Thrombotic Risk Prediction

George Davidson · International Journal of Research and Reports in Hematology · 2026

Artificial intelligence (AI) is rapidly transforming the landscape of thrombosis research, offering novel opportunities to enhance the understanding and prediction of platelet-driven thrombotic events. Platelets play a central role in hemostasis and pathological thrombosis, yet c...

Open access Research Article 10.9734/ijr2h/2026/v9i1221

Comparison of Activated Partial Thromboplastin and Prothrombin Time Among Different Abo Blood Groups

Eledo, Benjamin Onyema · International Journal of Research and Reports in Hematology · 2026

The categorization of human blood into specific groups is a cornerstone in both clinical medicine and genetics, playing a vital role in procedures such as blood transfusion, organ transplantation, and maternal-fetal immune compatibility. Among the numerous blood group classificat...

Open access Research Article 10.9734/ijr2h/2026/v9i1220

Diagnostic Outcomes of Bone Marrow Aspirations at the University of Port Harcourt Teaching Hospital: A Ten Year Retrospective Study

Emmanuel Wobo, Ezenwa-Ahanene Chidiadi, Paxman Dandyson Uku, Akpevwe Deborah Maduka & Kelvin Odede Guembe · International Journal of Research and Reports in Hematology · 2026

Introduction: Bone marrow aspiration is an established procedure for the diagnosis and management of a wide range of haematological and non-haematological conditions worldwide. The main aim of this study was to assess the diagnostic outcome of bone marrow aspiration at the Univer...

Open access Research Article 10.9734/ijr2h/2026/v9i1219

Comparative Evaluation of Whole Blood Clotting Time and Platelet Count among Post-Menopausal and Reproductive-Age Women in Elele, Nigeria

Eledo, Benjamin Onyema · International Journal of Research and Reports in Hematology · 2026

Menopause represents a critical physiological transition in a woman's life, marked by significant hormonal changes. Platelets are small blood cells that play a crucial role in the process of haemostasis, which is the body's mechanism for stopping bleeding after an injury. This st...

Open access Research Article 10.9734/ijr2h/2026/v9i1218

Socio-Cultural and Economic Determinants of Maternal Health-Seeking Behaviour for Neonatal Jaundice in Northern Ghana: A Qualitative Study

Deborah Azalekor, Keren-Happuch Twumasiwaa Boateng, Joyce Kanton & Alberta Gyepi Garbrah · International Journal of Research and Reports in Hematology · 2026

Background: The maternal behaviour of seeking healthcare services is crucial in promptly identifying and treating newborn jaundice. Swift identification and intervention are crucial in order to avert problems and guarantee the welfare of the neonate. Various factors can impact th...

Open access Research Article 10.9734/ijr2h/2026/v9i1217

Red Cell Functional Plasticity in Gestation: Beyond Indices to Oxygen-Sensing and Rheology

Emmanuel I. Obeagu & Okwudili B. Nwankwo · International Journal of Research and Reports in Hematology · 2026

Background: Pregnancy induces coordinated hematologic adaptations to sustain maternal–fetal oxygen exchange. While clinical assessment traditionally relies on red cell indices such as hemoglobin concentration, hematocrit, and mean corpuscular volume, these static measures incompl...

Open access Research Article 10.9734/ijr2h/2026/v9i1216

Extended Half-life Versus Standard Half-life Factor Replacement Therapy in Hemophilia A and B: A Systematic Review and Meta-analysis

Kwesi Akonu Adom Mensah Forson, Obiageri Ihuarulam Okeoma, Oluchi Okechukwu, Chidinma Lorretta Gab-Obinna, Enobong Edoabasi Obong, Richard Afriyie Osei & Jazuli Isyaku Bala · International Journal of Research and Reports in Hematology · 2026

Hemophilia is a congenital bleeding disorder that requires frequent factor replacement therapies to manage bleeding episodes. This systematic review and meta-analysis compares the efficacy of extended half-life (EHL) and standard half-life (SHL) factor replacement therapies in pa...

Open access Research Article 10.9734/ijr2h/2026/v9i1215

Knowledge, Attitude and Acceptance of Autologous Stem Cell Transplantation amongst Patients with Multiple Myeloma in Nigeria

Emmanuel Wobo, Ifechukwude Anita Osunde, Adaeze Onyinyechi Okwu, Linda Anucha Dublin-Green, Chinyere Eunice Eze, Akpevwe Deborah Maduka, Opadeyi Oluseyi Michael, Okwummuo Emeka Paul, Otumu Odianosen Sunday, Oji Anya Nnachi & Eniefiok Hezekiah Jumbo · International Journal of Research and Reports in Hematology · 2026

Background: The treatment of newly diagnosed Multiple Myeloma continues to evolve rapidly. Autologous stem cell transplantation remains the backbone in the management of the MM even in the era of novel agents. This procedure is not readily available in Nigeria AIM; To assess the...

Open access Research Article 10.9734/ijr2h/2026/v9i1213

Effects of Azadirachta indica on Obesity in Serum Liver Function Test Parameters and Physical Obesity Markers in High-Fat Diet Induced Obesity in Albino Rats

Anafi, O.H., Sahabi S. M. & Abubakar, M. S. · International Journal of Research and Reports in Hematology · 2026

Introduction: Obesity is a serious health challenge worldwide and is associated with various comorbidities, including dyslipidemia, type 2 diabetes and cardiovascular disease. Obesity is a challenging clinical condition to treat, because of their complex environmental components...

Open access Research Article 10.9734/ijr2h/2026/v9i1214

Beyond Hemoglobin S: Systems Biology Insights into the Multisystem Nature of Sickle Cell Disease: A Narrative Review

Emmanuel I. Obeagu & Okwudili B. Nwankwo · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell disease (SCD) is classically defined by a single-point mutation in the β-globin gene leading to hemoglobin S polymerization and erythrocyte sickling. However, accumulating evidence indicates that SCD is a complex multisystem disorder characterized by chron...

Open access Research Article 10.9734/ijr2h/2026/v9i1212