Background: Metabolic associated fatty liver disease (MAFLD) is a new definition proposed by the global consensus panel in 2020 for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and risk factors...
Open access
Research Article10.9734/irjgh/2024/v7i1106
Background: A bone marrow biopsy is routinely done prior to surgical intervention in patients with Extrahepatic portal venous obstruction (EHPVO) and Non-Cirrhotic portal fibrosis (NCPF) to rule out other aetiologies pertaining to pancytopenia. However, there are no guidelines fo...
Open access
Research Article10.9734/irjgh/2024/v7i1105
This case report presents a 31-year-old male with a complex interplay of cardiac, hepatic, and renal dysfunction, characterized by extra-hepatic portal venous obstruction (EHPVO), decompensated chronic liver disease (DCLD), and rheumatic heart disease (RHD) with severe mitral ste...
Open access
Research Article10.9734/irjgh/2024/v7i1104
Background: Cadmium, a known genotoxic metal, has been shown to worsen colonic damage in both animal models and human studies. Research has indicated that cadmium accumulation in the colon results in mucosal damage, inflammation, disrupted immune responses, and an increased risk...
Introduction: Helicobacter pylori is a highly evolved and adapted pathogen, notorious for having infected half of all the people in the world. It is linked as a causative agent for numerous benign and malignant diseases of the digestive tract, such as peptic ulcer disease (PUD) a...
Aim: The present study aimed to assess the levels of some oxidative stress markers in malaria parasite-infected subjects attending Rivers State University Teaching Hospital, Port Harcourt, Nigeria. Background: Malaria can be fatal, the severity of malaria infection is closely lin...
Background: Non-alcoholic steatohepatitis (NASH) is emerging as a significant global health challenge, closely linked to obesity and metabolic disorders. Despite its increasing prevalence, effective pharmacotherapy remains limited. Resmetirom, a selective thyroid hormone receptor...
Objective: To gather expert perspectives on the use of esomeprazole monotherapy or its combination with domperidone for managing acid-peptic disease (APD) in routine Indian settings. Methods: This cross-sectional study employed a 24-item questionnaire to gather expert opinions on...
Background: An endocrine and metabolic disease of the pancreas such as Diabetes Mellitus (DM), is of Public health dimension responsible for 536.6 million cases in the globe. The treatment of DM takes lots of resources, making alternative treatment options like the utilization of...
Background: Palm oil is an edible vegetable oil obtained from the mesocarp (reddish pulp) of the fruit of the oil palm trees. The present study evaluated the effects of sub-chronic consumption of palm oil-tainted feed (POTF) on hepatorenal parameters in male Wistar rats. Methods:...
Objective: To identify and evaluate the ideal therapeutic option for the management of gastroesophageal reflux disease (GERD) and associated nighttime heartburn in Indian settings with a special focus on rabeprazole prescription practice. Methods: The cross-sectional, multiple-re...
Since the inception of human civilization, mankind has used herbal medicine for the purpose of healing. This study aimed to examine the antidiabetic efficacy and lipid profile of Gymnema sylvestre. We assessed the antidiabetic activity using the alloxan-induced diabetic technique...
Almost since the dawn of human civilization, people have been employing herbal medicine as a means of treatment for various ailments. The anti-diabetic properties and lipid profile of Ficus benghalensis were investigated in this research. The anti-diabetic activity was measured b...
Aim: To assess some biochemical parameters (AST and ALT) and acute phase reactants (ESR and CRP) of plantain rosters in Port-Harcourt. Study Design: Cross-sectional study. Place and Duration of Study: Eni-Yimini Laboratories Ltd Address Yenezue-Gene, Epie, Yenagoa, Bayelsa State...
Non-alcoholic fatty liver disease (NAFLD) is a significant and pertinent human ailment linked to a modified way of life, characterized by a fast increasing occurrence and prevalence in the majority of countries worldwide. Non-alcoholic fatty liver disease (NAFLD) can lead to sign...