The present study was carried out to screen phytochemicals like carbohydrates, terpenoids, resins, saponins, tannins and alkaloids in the seed extract of Areca catechu by standard protocols and antibacterial activities of seed extract as well as silver nanoparticles prepared from...
Open access
Research Article10.9734/IJBCRR/2016/21864
Background: Fermented gruel (Ogi) has been reported to have high lactic acid bacteria (LAB) with proven probiotic properties. This fermented food has also has different therapeutic usages. Objective: The activities of fermented sorghum (Ogi) on induced hypercholesterolemia in alb...
Open access
Research Article10.9734/IJBCRR/2016/19659
Adipose tissue is a key player in whole body metabolism and excess adipose tissue poses a major risk factor for the development of metabolic disorders such as type 2 diabetes. In response to nutritional overload, de novo adipocyte differentiation can serve as an adaptive mechanis...
Open access
Research Article10.9734/IJBCRR/2016/18221
Background and Objectives: Polycystic ovarian disease (PCOS) is probably the most prevalent endocrinological disorder affecting females and is the most common cause of menstrual disturbance during the reproductive age. It is characterized by polycystic ovaries on ultrasound and/o...
Open access
Research Article10.9734/IJBCRR/2016/21676
The aim of this study was to determine the median lethal dose (LD50) of the extracts (aqueous and ethanol) of S. hispidus stem bark. A modified Lorke’s (1983) method was used in this study. Varying doses of the extracts were administered orally to male albino rats. Treatment-rela...
Open access
Research Article10.9734/IJBCRR/2016/22036
Endoglucanase (EC3.2.1.4) from sorghum (S. bi-color) and millet (Pennisetum typhoides & Digitaria exilis) malts were purified to homogeneity through the methods of ammonium sulphate precipitation and gel filtration. Molecular mass of 35 KDa and 41 KDa were determined by SDS-P...
Open access
Research Article10.9734/IJBCRR/2015/20593
Aim: We examine in this study the effect of two antitumor drugs metothrexate (MTX) and carboplatin (CPT) on the phospholipid content of plasma membrane of MCF-7 breast cancer cells. MTX is a folate analog that inhibit dihydrofolate reductase. CPT is a platinum-containing antineop...
Open access
Research Article10.9734/IJBCRR/2015/20709
Aim: The aim of the study was to screen the market classes of common beans popularly grown in Zambia for their polyphenolic phytochemical profiles. Methodology: Three market classes of common bean (red, grey mottled and brown) were investigated for their polyphenolic phytochemica...
Open access
Research Article10.9734/IJBCRR/2015/21608
The use of herbal remedies in various local communities throughout the world to assuage the scourge of indigenous diseases has gained tremendous popularity. One of the many plants species of herbal remedies is Moringa oleifera (horseradish) which has been widely used in West Afri...
Open access
Research Article10.9734/IJBCRR/2015/18455
Background: The Human Papilloma Virus (HPV) has evolved as a new culprit of malignant and pre malignant oral lesions. The objective of this study was to find out the frequency of HPV and its high risk genotypes in different lesions of oral cavity of tobacco chewers. Methods: From...
Open access
Research Article10.9734/IJBCRR/2015/20761
Aims: The aim of this study was to determine the effect of food deprivation on the body weight and blood glucose level of Wistar albino rats. Methodology: Blood samples were collected from the rats through ocular puncture at intervals and were used for the analysis of blood gluco...
Open access
Research Article10.9734/IJBCRR/2015/20721
Background: The annual number of new cases of hepatocellular carcinoma (HCC) worldwide is over 1 million. In developing countries, the major cause of HCC is chronic hepatitis C virus (HCV) infection. Various studies have reported an association between functional gene polymorphis...
Open access
Research Article10.9734/IJBCRR/2015/20013
Aims: This study was designed to evaluate the effect of aqueous and ethanolic extracts of stem bark from Trichilia emetica on the cellular immunity markers (TCD4+ count, Lymphocytes, WBC, RBC) in rats wistar. Study Design: Forty-two rats have been divided into seven groups of six...
Open access
Research Article10.9734/IJBCRR/2015/19629
Diarrhea results from an imbalance between the absorptive and secretary mechanisms in the intestinal tract, accompanied by watery bowel movement resulting in excess fluid and electrolytes in faeces. This study was undertaken to evaluate the effect of chloroform-ethanol extracts o...
Open access
Research Article10.9734/IJBCRR/2015/19854
Aims: To estimate fasting plasma glucose (FPG), serum ferritin, HbA1c and serum nitric oxide levels in type 2 diabetes mellitus (DM) subjects and compare the values with non diabetic individuals and also to assess the correlation analysis between the biochemical parameters in typ...
Open access
Research Article10.9734/IJBCRR/2015/19982