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All published articles 999

The Importance of the RAS Interacting with the HGF/C-Met Receptor System in Hypertensive Type 2 Diabetes Mellitus

John W. Wright & Joseph W. Harding · International Journal of Biochemistry Research & Review · 2014

The classic renin-angiotensin system (RAS) is described as a circulating hormone system with primary roles in the regulation of blood pressure, body water balance and thirst and control over vasopressin and aldosterone release. Recently local tissue RASs have been identified with...

Open access Research Article 10.9734/IJBCRR/2014/6569

Effect of Sublethal Concentration of Heavy Metal Contamination on Soil Physicochemical Properties, Catalase and Dehydrogenase Activities

Linus A. Nwaogu, Cosmas O. Ujowundu, Callistus I. Iheme, Tobias N. I. Ezejiofor & Donatus C. Belonwu · International Journal of Biochemistry Research & Review · 2014

The effect of sublethal contaminations (100 mg/dm3) of heavy metals such as mercury (Hg), lead (Pb) and cadmium (Cd) on soil enzyme and physicochemical properties was investigated after one hundred and twenty days. Soil sample without heavy metal contamination served as the contr...

Open access Research Article 10.9734/IJBCRR/2014/6341

Total Antioxidant Capacity: Correlation with Other Antioxidants and Clinical Utility of Their Levels in Chronic Obstructive Pulmonary Disease

Vivek Ambade, Alka Sontakke & Dashrath Basannar · International Journal of Biochemistry Research & Review · 2014

Aims: Oxidative stress is one of the major pathophysiologic hallmarks in the development of COPD and lung is protected against this by enzymatic and non-enzymatic antioxidants.  Total antioxidant activity (TAC), may give more relevant biological information about the individual's...

Open access Research Article 10.9734/IJBCRR/2014/7264

Comparative Evaluation of in vitro Antioxidant Properties of Cajanus cajan Seed and Moringa oleifera Leaf Extracts

Ilesanmi Funmilayo Florence, Akinloye Oluseyi Adeboye & Ilesanmi Olayinka Stephen · International Journal of Biochemistry Research & Review · 2014

Aims: This study was carried out to compare the antioxidant potentials of hydro-methanolic extracts of seed of Cajanus cajan and the leaf of Moringa oleifera. These plants have been associated with alleviating oxidative stress related conditions. Place and Duration of Study: Depa...

Open access Research Article 10.9734/IJBCRR/2014/6460

Effects of Orlistat and Herbal Mixture Extract on Renal Function and Oxidative Stress Biomarkers in a Rat Model of High Fat Diet

Kamal A. Amin, Sana'a R. Galaly, Wala'a G. Hozayen & Shima'a M. Ramadan · International Journal of Biochemistry Research & Review · 2014

Aims: This study was designed to assess the effectiveness of herbal mixture extracts of pumpkin seed oil, peanuts shell and Orlistat on renal function and oxidative stress biomarkers in male albino rats administrated high fat diet (HFD). Study Design: Fifty male rats were divided...

Open access Research Article 10.9734/IJBCRR/2014/6262

Hepatoprotective Effects of Crude Extracts of Tomato and Onion in Rats Exposed to Locally Processed Beef

C. O. Ujowundu, H. N. Okoye, R. N. Nwaoguikpe, D. C. Belonwu, K. O. Igwe & F. N. Ujowundu · International Journal of Biochemistry Research & Review · 2014

This study was carried out to examine the hepatoprotective effect of ethylacetate extract of tomatoes and methanol extract of onions on the biochemical changes induced by feed formulated with 15% roasted beef and 85% rats pellets. Doses of 500 mg/kg body weight of both extracts w...

Open access Research Article 10.9734/IJBCRR/2014/7353

Glucide Factors of the Inflorescence Sap of Four Coconut (Cocos nucifera L.) Cultivars from Côte D’ivoire

Konan N’Guessan Ysidor, Assa Rebecca Rachel, Konan Konan Jean-Louis, Okoma Djeya Muriel, Alexia Prades, Allou Kouassi & Biego Godi Henri Marius · International Journal of Biochemistry Research & Review · 2014

Aim: To assess physicochemical characters related to the glucide contents of the sap provided by four coconut cultivars.   Study Design: Thirty-six coconut saps from thirty-six healthy coconut trees inflorescences, replicated two times. Trees were randomly selected; cultivars wer...

Open access Research Article 10.9734/IJBCRR/2014/7148

Hematological Values in Sheep Fed a Diet Containing Black Cumin (Nigella sativa) Seed Oil

M. I. Abd El-Halim, Nabiela M. El-Bagir & M. K. Sabahelkhier · International Journal of Biochemistry Research & Review · 2014

The aim of this study was to investigate changes in hematological values after feeding diet mixed with oil pressed from seeds of Nigella sativa in sheep. The results indicated that there was no effect on the total Red Blood Cells (RBCs) count due to treatment when compared to the...

Open access Research Article 10.9734/IJBCRR/2014/7382

Comparative Effects of Aloe vera Gel and Aqueous Leaf Extract of Viscum album on Bilirubin Excretion in Streptozotocin - Induced Diabetic Rats

Nna Victor Udo, Ofem Ofem Effiong, Oka Victor Otu, Aluko Esther Olusola & Ofutet Emmanuel Oleba · International Journal of Biochemistry Research & Review · 2013

Aims: This study was carried out to determine the effect of type 1 Diabetes Mellitus on bilirubin excretion and to compare the effects of separate administration of Aloe vera gel and aqueous leaf extract of Viscum album on serum bilirubin, bile secretory rate and biliary bilirubi...

Open access Research Article 10.9734/IJBCRR/2014/7512

Effects of Aegopodium podagraria Preparations on the Metabolic Disorders Induced in Rats by Excess Fructose Combined WITH Hydrochlorothiazide: The Relationship between Influence on Electrolyte and Carbohydrate Metabolism

Olga Tovchiga · International Journal of Biochemistry Research & Review · 2013

Aims: To evaluate the effect of Aegopodium podagraria aerial part extract and tincture on electrolyte, glucose and uric acid metabolism in rats receiving excess fructose (10% drinking solution) combined with hydrochlorothiazide (20 mg/kg). Study Design: Fourty-two male rats were r...

Open access Research Article 10.9734/IJBCRR/2014/7201

Cross Talk between Oxidative Stress, PPAR- γ and RAS System in Diabetic Rat Heart Exposed to Ischemia / Reperfusion Injury

Maha M. Sabry, Nagwa K. Roshdy, Laila A. Rashed, Hany E. ElSebaee, Mary A. Youssef & Amal F. Tawadrous · International Journal of Biochemistry Research & Review · 2013

Introduction: The present study aimed at clarifying the cross talk between peroxisome  proliferator-activated receptor-gamma (PPAR- γ), cardiac reactive Oxygen species (ROS) and Renin-Angiotensin System (RAS). Methods: A total of 90 male albino rats were used. The rats were divid...

Open access Research Article 10.9734/IJBCRR/2014/6009

History and Biology of Transglutaminase 2: A Synopsis

Odii Benedict Onyekachi & Peter Coussons · International Journal of Biochemistry Research & Review · 2013

Transglutaminase 2 (TG2) belongs to the family of transglutaminase, a large group of intracellular and extracellular enzymes that primarily catalyze the Ca2+-dependent post-translational modification of proteins. Discovery of the first transglutaminase in the early 1920s, has sub...

Open access Research Article 10.9734/IJBCRR/2014/6363

Establishment of cDNA Library and EST Analysis from Leaves of Phyllanthus amarus

Sharmila Chattopadhyay & Aparupa Bose Mazumdar Ghosh · International Journal of Biochemistry Research & Review · 2013

DNA sequencing of randomly chosen clones from a cDNA library allows thousands of different transcripts to be identified. However, since the likelihood of observing a given transcript is proportional to the expression level of that transcript in the tissue from which the library i...

Open access Research Article 10.9734/IJBCRR/2014/5262

Evaluation of the Concentration of Selected Heavy Metals and the Effects on Soil Enzymatic Activities in an Abandoned Cement Factory Nigercem Nkalagu and Its Environs

Orinya Onyebuchi Frederick, Akubugwo Emmanuel Iroha & Edeogu Chukwu Oswald · International Journal of Biochemistry Research & Review · 2013

This study investigated the concentrations of heavy metals, the activities of some selected enzymes and the pH of the soil surface (1-10 cm) and depth (11-20 cm) within the vicinity of an abandoned cement factory Nigercem Nkalagu, and further away 1km from the factory centre. The...

Open access Research Article 10.9734/IJBCRR/2014/5019

Preparation, Characterization, Theoretical Treatment and Adsorption on SurfacesN5AcyclicImmobilizes on Silica Gel for Removal of Some Toxic Metals

Omar Hamad Shehab AL- Obaidi & Mahmoud N. Al-Jibouri · International Journal of Biochemistry Research & Review · 2013

A series of transition elements complexes with [2,6-diacetimino-pheylenediamine –[2,2,diyl] pyridine] of the general formula [MLCl]Clx, (where M= Cr(III), Pb(II), Zn(II) and Cd(II), x= 2 for Cr(III)) respectively have been synthesized  and  fully characterized  on the bases of C....

Open access Research Article 10.9734/IJBCRR/2014/5198